Michael Tal
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View article: Prospective evaluation of efficacy and safety of distal radial and radial artery access using a novel articulating-tip guidewire
Prospective evaluation of efficacy and safety of distal radial and radial artery access using a novel articulating-tip guidewire Open
Background: Guidewire-facilitated access to peripheral vessels is commonplace in vascular access, but guidewire insertion into small vessels, such as the radial and distal radial arteries, can still be challenging. Failure to gain access o…
View article: Placebo or Nocebo Interventions as Affected by Hypnotic Susceptibility
Placebo or Nocebo Interventions as Affected by Hypnotic Susceptibility Open
The purpose of the present study was to examine placebo and nocebo effects under hypnotic analgesia in lowly hypnotizable (LH) and highly hypnotizable (HH) subjects. A placebo and nocebo, obtained in a two-step intervention (verbal expecta…
View article: Pressure-Induced Fibroid Ischemia: First-In-Human Experience with a Novel Device for Laparoscopic Treatment of Symptomatic Uterine Fibroids
Pressure-Induced Fibroid Ischemia: First-In-Human Experience with a Novel Device for Laparoscopic Treatment of Symptomatic Uterine Fibroids Open
The purpose of this study was to assess the feasibility of use of a novel uterine fibroid treatment device hypothesized to cause fibroid infarction by increasing intra-tumoral pressure. Between August 2019 and January 2020, 21 uterine fibr…
View article: Deletion of CD47 from Schwann cells, macrophages and microglia hastens myelin disruption and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages and microglia
Deletion of CD47 from Schwann cells, macrophages and microglia hastens myelin disruption and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages and microglia Open
Background : Myelin that surrounds axons breaks in trauma and disease; e.g., PNI and SCI (peripheral nerve and spinal cord injuries) and MS (multiple sclerosis). Resulting myelin debris hinders repair if not effectively scavenged by Schwan…
View article: Initial Clinical Experience with a Symmetric Tip Tunneled Hemodialysis Catheter Without Side Holes
Initial Clinical Experience with a Symmetric Tip Tunneled Hemodialysis Catheter Without Side Holes Open
The purpose of this article is to assess the performance and safety of a novel, symmetric, side-hole–free tunneled cuffed catheter hypothesized to sustain adequate flow without the need for side holes. Between November 2016 and January 201…
View article: Inframalleolar access in endovenous treatment of venous ulcers and C5 disease with nonthermal nontumescent techniques
Inframalleolar access in endovenous treatment of venous ulcers and C5 disease with nonthermal nontumescent techniques Open
NTNT ablation techniques using inframalleolar access are effective and safe without risk of nerve damage. Their use facilitates ulcer healing and limits pain in patients with advanced disease.
View article: Catheter-related blood stream infection in hemodialysis patients with symmetric tunneled non-side-hole hemodialysis catheters
Catheter-related blood stream infection in hemodialysis patients with symmetric tunneled non-side-hole hemodialysis catheters Open
Background: Tunneled hemodialysis catheter-related bloodstream infection is a major cause of morbidity and mortality in end-stage renal disease patients. Side holes positioned near the tip of catheters have been linked to formation of thro…
View article: <i>Staphylococcus aureus</i> accumulation at the tip of hemodialysis catheters with or without tip side holes in catheter related bloodstream infection in a large animal
<i>Staphylococcus aureus</i> accumulation at the tip of hemodialysis catheters with or without tip side holes in catheter related bloodstream infection in a large animal Open
Background: Eighty percent of hemodialysis patients start their dialysis with a tunneled hemodialysis catheter. Catheter related bacteremia is the second most common cause of death in these patients. Side holes near the tips of the tunnele…
View article: Reduced nontarget embolization and increased targeted delivery with a reflux-control microcatheter in a swine model
Reduced nontarget embolization and increased targeted delivery with a reflux-control microcatheter in a swine model Open
In an animal model, RCM microcatheters reduce the risk of non-target embolization from 11% to 1.7%, increasing the delivery of microspheres of 98% to the target vessels, compared to SEHM microcatheters.
View article: Clot accumulation at the tip of hemodialysis catheters in a large animal model
Clot accumulation at the tip of hemodialysis catheters in a large animal model Open
Background: The issue of side holes in the tips of the tunneled cuffed central venous catheters is complex and has been subject to longstanding debate. This study sought to compare the clotting potential of the side-hole-free Pristine hemo…
View article: Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge
Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge Open
Pneumococcal flavin reductase (FlaR) is known to be cell-wall associated and possess age dependent antigenicity in children. This study aimed at characterizing FlaR and elucidating its involvement in pneumococcal physiology and virulence. …
View article: Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine
Streptococcus pneumoniae Cell-Wall-Localized Phosphoenolpyruvate Protein Phosphotransferase Can Function as an Adhesin: Identification of Its Host Target Molecules and Evaluation of Its Potential as a Vaccine Open
In Streptococcus pneumonia, phosphoenolpyruvate protein phosphotransferase (PtsA) is an intracellular protein of the monosaccharide phosphotransferase systems. Biochemical and immunostaining methods were applied to show that PtsA also loca…
View article: Streptococcus pneumoniae fructose-1, 6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice
Streptococcus pneumoniae fructose-1, 6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice Open
Streptococcus pneumoniae (S. pneumoniae) is a major pathogen worldwide. The currently available polysaccharide-based vaccines significantly reduce morbidity and mortality. However, the inherent disadvantages of the currently available poly…