Talia Caspi
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View article: 167 Impact of early introduction and uptitration of evidence-based heart failure medications on one-year mortality rates
167 Impact of early introduction and uptitration of evidence-based heart failure medications on one-year mortality rates Open
Introduction Heart failure (HF) mortality rates continue to pose a significant challenge despite advancements in recent decades – in the UK, one-year mortality rates are approximately 20%, ranging up to 30% globally among HF patients.1, 2 …
View article: Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy
Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy Open
Background People with chronic heart failure (CHF) experience severe skeletal muscle dysfunction, characterized by mitochondrial abnormalities, which exacerbates the primary symptom of exercise intolerance. However, the molecular triggers …
View article: Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure
Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure Open
Background Previous studies in heart failure with reduced ejection fraction (HFrEF) suggest that skeletal muscle mitochondrial impairments are associated with exercise intolerance in men. However, the nature of this relationship in female …
View article: PTU-083 Time of day influences colonoscopy outcome measures
PTU-083 Time of day influences colonoscopy outcome measures Open
Introduction Endoscopic surveillance and removal of adenomas significantly reduces the incidence and mortality of colorectal cancer. There is concern that time of day could affect colonoscopy outcomes due to endoscopist fatigue over the co…