Tamara A. Dailey
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View article: The alternative coproporphyrinogen III oxidase (CgoN) catalyzes the oxygen-independent conversion of coproporphyrinogen III into coproporphyrin III
The alternative coproporphyrinogen III oxidase (CgoN) catalyzes the oxygen-independent conversion of coproporphyrinogen III into coproporphyrin III Open
Nature utilizes three distinct pathways to synthesize the essential enzyme cofactor heme. The coproporphyrin III-dependent pathway, predominantly present in Bacillaceae , employs an oxygen-dependent coproporphyrinogen III oxidase (CgoX) th…
Erythropoietin signaling regulates heme biosynthesis Open
Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation …
Author response: Erythropoietin signaling regulates heme biosynthesis Open
Full text Figures and data Side by side Abstract eLife digest Introduction Results Discussion Materials and methods References Decision letter Author response Article and author information Metrics Abstract Heme is required for survival of…
View article: Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product
Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product Open
SUMMARY The advent of heme during evolution allowed organisms possessing this compound to safely and efficiently carry out a variety of chemical reactions that otherwise were difficult or impossible. While it was long assumed that a single…