Tamara Caldaro
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View article: Innovative endoscopic alternatives for the conservative management of recurrent/refractory esophageal strictures in children: A case series
Innovative endoscopic alternatives for the conservative management of recurrent/refractory esophageal strictures in children: A case series Open
BACKGROUND Refractory esophageal strictures (ES) are defined an anatomical restriction without an active endoscopic inflammation resulting in dysphagia after a minimum of five seriated dilatations in a 4-weeks interval. Recurrent ES (REES)…
View article: Management of oesophageal strictures in inherited epidermolysis bullosa: a clinical practice guideline
Management of oesophageal strictures in inherited epidermolysis bullosa: a clinical practice guideline Open
Inherited epidermolysis bullosa (EB) is a group of rare and complex genetic disorders characterized by fragility of the skin and mucous membranes. Specifically, the gastrointestinal tract is commonly involved with a range of complications,…
View article: Endoscopic retrograde cholangiopancreatography in children with pediatric congenital biliary dilatation associated with pancreatobiliary maljunction: experience from a tertiary center
Endoscopic retrograde cholangiopancreatography in children with pediatric congenital biliary dilatation associated with pancreatobiliary maljunction: experience from a tertiary center Open
Background Congenital biliary dilatation (CBD) is a congenital malformation of the main biliary tract usually associated with the pancreatobiliary maljunction (PBM), determining stone formation, cholangitis, pancreatitis, and cholangiocarc…
View article: Diagnosis and Management of Congenital H-Type Tracheoesophageal Fistula: Results of a National Survey
Diagnosis and Management of Congenital H-Type Tracheoesophageal Fistula: Results of a National Survey Open
Background: Congenital h-type tracheoesophageal fistula (H-TEF) without esophageal atresia (EA) represents about 4% of congenital esophageal anomalies. The diagnosis is challenging, and surgery is considered curative. The aim was to report…
View article: Major Abdominal Surgery for Pediatric Crohn’s Disease in the Anti-TNF Era: 10-Year Analysis of Data From the IBD Registry of Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition
Major Abdominal Surgery for Pediatric Crohn’s Disease in the Anti-TNF Era: 10-Year Analysis of Data From the IBD Registry of Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition Open
Background The natural history of Crohn’s disease (CD) can result in complications requiring surgery. Pediatric data are scarce about major abdominal surgery. The IBD Registry from the Italian Society of Pediatric Gastroenterology, Hepatol…
View article: Case report: Neonatal-onset inflammatory bowel disease due to novel compound heterozygous mutations in DUOX2
Case report: Neonatal-onset inflammatory bowel disease due to novel compound heterozygous mutations in DUOX2 Open
Very Early Onset Inflammatory Bowel Disease (VEO-IBD) is potentially associated with genetic disorders of the intestinal epithelial barrier or inborn errors of immunity (IEI). Dual oxidase 2 (DUOX2), an H 2 O 2 -producing NADPH oxidase exp…
View article: Neurological impairment and malnutrition in children: The role of home enteral nutrition in real life
Neurological impairment and malnutrition in children: The role of home enteral nutrition in real life Open
Objective Recent decades have brought an increased survival of children with Neurologic Impairment (NI) but malnutrition and digestive comorbidity remain important challenges to face. We designed the present study to assess the course of n…
View article: New frontiers for therapeutic endoscopic ultrasound in children
New frontiers for therapeutic endoscopic ultrasound in children Open
Therapeutic endoscopic ultrasound is a well-established tool for several gastrointestinal disorders in adults. Diffusion in children is still limited but it can represent an effective, non-invasive option. A selection of relevant clinical …
View article: Decellularized esophageal tubular scaffold microperforated by quantum molecular resonance technology and seeded with mesenchymal stromal cells for tissue engineering esophageal regeneration
Decellularized esophageal tubular scaffold microperforated by quantum molecular resonance technology and seeded with mesenchymal stromal cells for tissue engineering esophageal regeneration Open
Current surgical options for patients requiring esophageal replacement suffer from several limitations and do not assure a satisfactory quality of life. Tissue engineering techniques for the creation of customized “self-developing” esophag…
View article: Emergency management in epidermolysis bullosa: consensus clinical recommendations from the European reference network for rare skin diseases
Emergency management in epidermolysis bullosa: consensus clinical recommendations from the European reference network for rare skin diseases Open
Epidermolysis bullosa (EB) comprises a group of genetic disorders with the hallmark of fragility of the skin and mucosal surfaces. The severity of different types of EB varies markedly as does the occurrence of extra-cutaneous involvement …
View article: Targeting Epidermal Growth Factor Receptor (EGFR) in Pediatric Colorectal Cancer
Targeting Epidermal Growth Factor Receptor (EGFR) in Pediatric Colorectal Cancer Open
Background: Colorectal carcinoma (CRC) is very rare in the pediatric and adolescent age range and clinical management is performed according to adult protocols. We report, for the first time in the literature, a case of a child with metast…
View article: Successful muscle regeneration by a homologous microperforated scaffold seeded with autologous mesenchymal stromal cells in a porcine esophageal substitution model
Successful muscle regeneration by a homologous microperforated scaffold seeded with autologous mesenchymal stromal cells in a porcine esophageal substitution model Open
Background: Since the esophagus has no redundancy, congenital and acquired esophageal diseases often require esophageal substitution, with complicated surgery and intestinal or gastric transposition. Peri-and-post-operative complications a…
View article: Pediatric Chronic Intestinal Failure in Italy: Report from the 2016 Survey on Behalf of Italian Society for Gastroenterology, Hepatology and Nutrition (SIGENP)
Pediatric Chronic Intestinal Failure in Italy: Report from the 2016 Survey on Behalf of Italian Society for Gastroenterology, Hepatology and Nutrition (SIGENP) Open
Background: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There …
View article: Anastomotic Strictures after Esophageal Atresia Repair: Incidence, Investigations, and Management, Including Treatment of Refractory and Recurrent Strictures
Anastomotic Strictures after Esophageal Atresia Repair: Incidence, Investigations, and Management, Including Treatment of Refractory and Recurrent Strictures Open
Improved surgical techniques, as well as preoperative and postoperative care, have dramatically changed survival of children with esophageal atresia (EA) over the last decades. Nowadays, we are increasingly seeing EA patients experiencing …
View article: An uncommon cause of abdominal pain in a child: Meckel diverticulum
An uncommon cause of abdominal pain in a child: Meckel diverticulum Open
Meckel diverticulum, a common congenital anomaly of the small intestine, can be responsible of several complications due to the presence of ectopic gastric mucosa and represents a challenge for diagnosis. We present the case of a 11-year b…