Tammy T. Y. Lau
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View article: A curated census of pathogenic and likely pathogenic UTR variants and evaluation of deep learning models for variant effect prediction
A curated census of pathogenic and likely pathogenic UTR variants and evaluation of deep learning models for variant effect prediction Open
Introduction: Variants in 5′ and 3′ untranslated regions (UTR) contribute to rare disease. While predictive algorithms to assist in classifying pathogenicity can potentially be highly valuable, the utility of these tools is often unclear, …
View article: Additional file 14 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 14 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 14: Table S6. BLASTX, Bowtie2, and taxonomic k-mer annotation of VK02 reads against CARD reference sequences.
View article: Additional file 9 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 9 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 9: Table S4. OPXV genomes used for comparison in the phylogenetic analyses.
View article: Additional file 8 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 8 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 8: Figure S4. Regression analyses of root-to-tip genetic distance on the ML phylogeny against either year of collection or year of sequencing.
View article: Additional file 6 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 6 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 6: Figure S2. Maximum likelihood trees for Mutter vaccine strains called in reference to alternative VACV genomes.
View article: Additional file 4 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 4 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 4: Table S2. Mapping statistics for human component of libraries VK01, VK02 and VK08.
View article: Additional file 5 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 5 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 5: Table S3. Summary statistics produced by QUAST for SPAdes de novo assemblies of VK01, VK02 and VK08 from shotgun data.
View article: Additional file 12 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 12 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 12: Table S5. OPXV genomes used for bait design.
View article: Additional file 2 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains
Additional file 2 of The origins and genomic diversity of American Civil War Era smallpox vaccine strains Open
Additional file 2: Table S1. Details of the libraries generated from the Mütter Museum vaccination kits and vaccinia virus mapping statistics.
View article: CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database Open
The Comprehensive Antibiotic Resistance Database (CARD; https://card.mcmaster.ca) is a curated resource providing reference DNA and protein sequences, detection models and bioinformatics tools on the molecular basis of bacterial antimicrob…