Tan Yong Chia
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View article: Hydrogen Sulfide and Nitric Oxide Improve Renal Function and α-Adrenergic Responsiveness in Rats with Left Ventricular Hypertrophy
Hydrogen Sulfide and Nitric Oxide Improve Renal Function and α-Adrenergic Responsiveness in Rats with Left Ventricular Hypertrophy Open
In left ventricular hypertrophy (LVH), the combined external administration of hydrogen sulfide (H2S) and nitric oxide (NO) has been shown to reverse LVH by activating the endothelial nitric oxide synthase pathway (eNOS/NO), independent of…
View article: Microbial contamination in aquatic ecosystems: implications for human health and disease prevention
Microbial contamination in aquatic ecosystems: implications for human health and disease prevention Open
Water-based ecosystems face serious public health concerns due to the microbial contamination of waters and the spread of waterborne diseases, as well as the dissemination of antibiotic-resistant microbes. Contaminants can be from natural …
View article: Acute and Subacute Oral Toxicity Assessment of The Polysaccharides Extracted from <i>Clinacanthus nutans</i> Leaves: A Preclinical Model for Drug Safety Screening
Acute and Subacute Oral Toxicity Assessment of The Polysaccharides Extracted from <i>Clinacanthus nutans</i> Leaves: A Preclinical Model for Drug Safety Screening Open
Emerging investigations have indicated that many plant polysaccharides may be beneficial for treating metabolic diseases. To date, the therapeutic efficacy and potential toxicity of polysaccharides extracted from Clinacanthus nutans (C. nu…
View article: ACUTE AND SUBACUTE ORAL TOXICITY ASSESSMENT OF THE POLYSACCHARIDES EXTRACTED FROM CLINACANTHUS NUTANS LEAVES: A PRECLINICAL MODEL FOR DRUG SAFETY SCREENING
ACUTE AND SUBACUTE ORAL TOXICITY ASSESSMENT OF THE POLYSACCHARIDES EXTRACTED FROM CLINACANTHUS NUTANS LEAVES: A PRECLINICAL MODEL FOR DRUG SAFETY SCREENING Open
Emerging investigations have indicated that many plant polysaccharides may be beneficial in treating metabolic diseases. Hitherto, the therapeutic efficacies and the potential toxicity of polysaccharides extracted from Clinacanthus nutans …
View article: A comprehensive review on the pancreatic lipase inhibitory peptides: A future anti-obesity strategy
A comprehensive review on the pancreatic lipase inhibitory peptides: A future anti-obesity strategy Open
Dysregulation of lipid homeostasis contributes to obesity and can directly lead to several critical public health concerns globally. This paper aimed to present a brief review of related properties and the use of pancreatic lipase inhibito…
View article: Mental Health Screening during COVID-19 Pandemic among School Teachers in Malaysia: A Cross-Sectional Study
Mental Health Screening during COVID-19 Pandemic among School Teachers in Malaysia: A Cross-Sectional Study Open
(1) Background: The teaching profession has become more challenging due to the increased use of information technology, which potentially increases psychological distress among teachers. This study aimed to determine the prevalence of depr…
View article: Correction: Hashmi et al. Hydrogen Sulphide Treatment Prevents Renal Ischemia-Reperfusion Injury by Inhibiting the Expression of ICAM-1 and NF-kB Concentration in Normotensive and Hypertensive Rats. Biomolecules 2021, 11, 1549
Correction: Hashmi et al. Hydrogen Sulphide Treatment Prevents Renal Ischemia-Reperfusion Injury by Inhibiting the Expression of ICAM-1 and NF-kB Concentration in Normotensive and Hypertensive Rats. Biomolecules 2021, 11, 1549 Open
In the published publication [...]
View article: A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine
A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine Open
The application of natural products and supplements has expanded tremendously over the past few decades. Clinacanthus nutans (C. nutans), which is affiliated to the Acanthaceae family, has recently caught the interest of researchers from t…
View article: Hydrogen Sulphide Treatment Prevents Renal Ischemia-Reperfusion Injury by Inhibiting the Expression of ICAM-1 and NF-kB Concentration in Normotensive and Hypertensive Rats
Hydrogen Sulphide Treatment Prevents Renal Ischemia-Reperfusion Injury by Inhibiting the Expression of ICAM-1 and NF-kB Concentration in Normotensive and Hypertensive Rats Open
Our main objective was to investigate the effect of chronic administration of hydrogen sulphide donor (sodium hydrosulphide) on the expression of intercellular adhesion molecule-1 (ICAM-1) and concentration of nuclear factor-kappa B (NF-kB…
View article: Inhibition of L-NAME-Induced Hypertension by Combined Treatment With Apocynin and Catalase: The Role of Nox 4 Expression
Inhibition of L-NAME-Induced Hypertension by Combined Treatment With Apocynin and Catalase: The Role of Nox 4 Expression Open
Reactive oxygen species (ROS) such as superoxide (O2-) generated by NAD(P)H oxidases have emerged as important molecules in blood pressure regulation. This study investigated the effect of apocynin and catalase on blood pressure and renal …
View article: The restorative effect of apocynin and catalase in l-arginine induced hypotension on normotensive subjects – the role of oxidative stress
The restorative effect of apocynin and catalase in l-arginine induced hypotension on normotensive subjects – the role of oxidative stress Open
L-arginine is a substrate for nitric oxide synthase (NOS) responsible for the production of NO. This investigation studied the effect of apocynin, an NADPH oxidase inhibitor and catalase, an H2O2 scavenger on L-arginine induced oxidative s…
Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats Open
View article: Chronic administration of apocynin and catalase ameliorates the blood pressure and renal functional parameters attributed by L-NAME induced systemic arterial hypertension in Wistar-Kyoto rats: The role of oxidative stress
Chronic administration of apocynin and catalase ameliorates the blood pressure and renal functional parameters attributed by L-NAME induced systemic arterial hypertension in Wistar-Kyoto rats: The role of oxidative stress Open
Event Abstract Back to Event Chronic administration of apocynin and catalase ameliorates the blood pressure and renal functional parameters attributed by L-NAME induced systemic arterial hypertension in Wistar-Kyoto rats: The role of oxida…