Rui Tang
YOU?
Author Swipe
View article: A New Class of Anionic Near-Infrared Fluorescent Dyes with 1,6-Diheterophenalene-2,5-dione End Groups
A New Class of Anionic Near-Infrared Fluorescent Dyes with 1,6-Diheterophenalene-2,5-dione End Groups Open
View article: Peptide-modified phase-transition nanoparticles co-deliver FTO siRNA and Ce6 for sonodynamic metabolism-immunotherapy of melanoma
Peptide-modified phase-transition nanoparticles co-deliver FTO siRNA and Ce6 for sonodynamic metabolism-immunotherapy of melanoma Open
This study demonstrated that si-Ce6@tLyP-1 NPs serve as a platform for targeted the tumor site and efficiently deliver siFTO and Ce6. The realization of FTO inhibition combined with SDT provides an effective treatment strategy for the trea…
View article: KOM: A Multi-Agent Artificial Intelligence System for Precision Management of Knee Osteoarthritis (KOA)
KOM: A Multi-Agent Artificial Intelligence System for Precision Management of Knee Osteoarthritis (KOA) Open
Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized multidisciplinary interventions have the potential to slow dise…
View article: KOM: A Multi-Agent Artificial Intelligence System for Precision Management of Knee Osteoarthritis (KOA)
KOM: A Multi-Agent Artificial Intelligence System for Precision Management of Knee Osteoarthritis (KOA) Open
Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized multidisciplinary interventions have the potential to slow dise…
View article: Inhibition of antiapoptotic BCL-2 proteins with Lipo-NPs induces fibroblast apoptosis, alleviating pulmonary fibrosis in VILI mice
Inhibition of antiapoptotic BCL-2 proteins with Lipo-NPs induces fibroblast apoptosis, alleviating pulmonary fibrosis in VILI mice Open
Background Mechanical ventilation in critically ill patients can potentially result in ventilator-induced lung injury (VILI). Additionally, mechanical stretching might activate the pro-fibrotic signaling pathways, which could contribute to…
View article: Ablation of CD38 in Multiple Myeloma Cells Leads to an Aggressive Phenotype in a Mouse Xenograft Model
Ablation of CD38 in Multiple Myeloma Cells Leads to an Aggressive Phenotype in a Mouse Xenograft Model Open
Multiple myeloma (MM) is a plasma cell malignancy characterized by bone pain and organ failure. A major challenge in treating MM is therapeutic resistance. CD38-targeted immunotherapies, such as daratumumab, have significantly improved out…
View article: Chemo-RaST with bortezomib inhibits multiple myeloma relapse
Chemo-RaST with bortezomib inhibits multiple myeloma relapse Open
Rationale: Multiple myeloma (MM) is a hematological malignancy with a high relapse rate that ultimately leads to patient mortality. Current therapies often fail to achieve sustained remission due to adaptation of clonally heterogene…
View article: Reversal of ischemic cortical blindness with tenecteplase
Reversal of ischemic cortical blindness with tenecteplase Open
View article: Preparation of a Bacterial Consortium for Straw Degradation and Optimization of Conditions for Its Return to the Field
Preparation of a Bacterial Consortium for Straw Degradation and Optimization of Conditions for Its Return to the Field Open
The yield of corn straw is huge, and returning straw to the field is an efficient utilization measure. The challenge in this approach is how to efficiently degrade the straw returned to the field. The study of efficient straw-degrading bac…
View article: Case Report: Breast ductal carcinoma in situ with microinvasion: a case tracked over 13 years
Case Report: Breast ductal carcinoma in situ with microinvasion: a case tracked over 13 years Open
Background Numerous studies have reported considerable heterogeneity in breast ductal carcinoma in situ with microinvasion (DCIS-MI) regarding clinical presentation, progression potential, and treatment strategies. Case presentation In thi…
View article: Peptide-modified phase-transition nanoparticles co-deliver FTO siRNA and Ce6 for sonodynamic metabolism-immunotherapy of melanoma
Peptide-modified phase-transition nanoparticles co-deliver FTO siRNA and Ce6 for sonodynamic metabolism-immunotherapy of melanoma Open
Background Melanoma, the most aggressive skin cancer, remains challenging to treat due to limited therapeutic options. Sonodynamic therapy (SDT) has emerged as a promising strategy for combating malignant tumors. However, the excessive acc…
View article: Self-assembled peptide nanofibers demonstrate tunable CD38 avidity
Self-assembled peptide nanofibers demonstrate tunable CD38 avidity Open
CD38 is overexpressed in multiple myeloma (MM) cells and consequently an important clinical target for therapeutic antibodies. However, the utility of CD38-binding antibodies for imaging has been limited by unfavorable pharmacokinetics. Pe…
View article: Geo-RepNet: Geometry-Aware Representation Learning for Surgical Phase Recognition in Endoscopic Submucosal Dissection
Geo-RepNet: Geometry-Aware Representation Learning for Surgical Phase Recognition in Endoscopic Submucosal Dissection Open
Surgical phase recognition plays a critical role in developing intelligent assistance systems for minimally invasive procedures such as Endoscopic Submucosal Dissection (ESD). However, the high visual similarity across different phases and…
View article: Enhanced Erythromycin Elimination from Erythromycin Fermentation Residue via Anaerobic Volatile Fatty Acid Production Under Mesophilic Conditions
Enhanced Erythromycin Elimination from Erythromycin Fermentation Residue via Anaerobic Volatile Fatty Acid Production Under Mesophilic Conditions Open
Erythromycin fermentation residue (EFR) is difficult to dispose of due to its high content of macrolide erythromycin. An alternative economic method was proposed in this study for erythromycin elimination in EFR through volatile fatty acid…
View article: Ultrasound Visualization of Spatiotemporal Autophagy-Regulated Nanodroplets for Amplifying ICB in Melanoma via Remodeling Tumor Inflammatory Microenvironment
Ultrasound Visualization of Spatiotemporal Autophagy-Regulated Nanodroplets for Amplifying ICB in Melanoma via Remodeling Tumor Inflammatory Microenvironment Open
Immune checkpoint blockade (ICB) therapy, represented by anti-PD-1/PD-L1 antibodies, is confronted with difficulties of unsatisfied response rates owing to the prevalence of "cold" immune tumor microenvironment (TME) in most cancers. Block…
View article: Imaging Peripheral Nerves In Vivo with CT Neurogram Using Novel 2,4,6-Tri-Iodinated Lidocaine Contrast Agent
Imaging Peripheral Nerves In Vivo with CT Neurogram Using Novel 2,4,6-Tri-Iodinated Lidocaine Contrast Agent Open
Peripheral nerve injuries are a significant concern in surgical procedures, often leading to chronic pain and functional impairment. Despite advancements in imaging, preoperative and intraoperative visualization of peripheral nerves remain…
View article: Low‐Intensity Focused Ultrasound‐Responsive, Phase‐Change Nanodroplets to Remodel Macrophage Polarization and Enhance PD‐L1 Blockade Therapy
Low‐Intensity Focused Ultrasound‐Responsive, Phase‐Change Nanodroplets to Remodel Macrophage Polarization and Enhance PD‐L1 Blockade Therapy Open
Immune checkpoint blockade (ICB) therapy is a promising treatment that has shown significant effects in certain refractory and advanced cancers. However, not all patients respond to ICB therapy. The tumor microenvironment (TME) helps tumor…
View article: Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy
Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy Open
Piezocatalyst‐enabled sonopiezoelectric therapy offers noninvasive treatment with high spatiotemporal selectivity, yet existing piezocatalysts are limited by suboptimal efficacy, cancer cell resistance to oxidative stress, and biosafety co…
View article: Dissecting biological heterogeneity in major depressive disorder based on neuroimaging subtypes with multi-omics data
Dissecting biological heterogeneity in major depressive disorder based on neuroimaging subtypes with multi-omics data Open
The heterogeneity of Major Depressive Disorder (MDD) has been increasingly recognized, challenging traditional symptom-based diagnostics and the development of mechanism-targeted therapies. This study aims to identify neuroimaging-based MD…
View article: Case Report: Persistent toxic reactions in a toddler with a negative blood cantharidin toxicology test
Case Report: Persistent toxic reactions in a toddler with a negative blood cantharidin toxicology test Open
Cantharidin is a potent natural toxin and has been used in traditional Chinese medicine to treat cancers and various ailments such as rabies or psoriasis. However, improper use of cantharidin can easily lead to poisoning. Despite there is …
View article: Analysis of acute non-pharmaceutical toxic exposures in children: a 5-year retrospective study
Analysis of acute non-pharmaceutical toxic exposures in children: a 5-year retrospective study Open
Objective This study aims to systematically analyze the epidemiological characteristics, clinical interventions and outcomes of children with acute non-pharmaceutical toxic exposures. Methods This retrospective study included all children …
View article: The impact of different left heart decompression strategies and timing on VA-ECMO patients: a systematic review and network meta-analysis
The impact of different left heart decompression strategies and timing on VA-ECMO patients: a systematic review and network meta-analysis Open
View article: Tree-Related High-Impedance Fault in Distribution Systems: Modeling, Detection, and Ignition Risk Assessment (Review)
Tree-Related High-Impedance Fault in Distribution Systems: Modeling, Detection, and Ignition Risk Assessment (Review) Open
Tree-related high-impedance faults (THIFs) in medium voltage distribution systems represent a typical fault, especially where an overhead line crosses a forested area. The arc caused by THIFs could ignite nearby combustibles, significantly…
View article: Fault Direction Identification in Distribution Networks Using Sequence Current Phase Difference under Distributed Photovoltaic Integration
Fault Direction Identification in Distribution Networks Using Sequence Current Phase Difference under Distributed Photovoltaic Integration Open
View article: Super-compact wideband bandpass Filter (BPF) with a single notched band incorporating T-shaped stub resonators and defected ground structures
Super-compact wideband bandpass Filter (BPF) with a single notched band incorporating T-shaped stub resonators and defected ground structures Open
View article: WT-Fault-LLM:Knowledge Graph Enhanced Large Model for Wind-turbine Faults
WT-Fault-LLM:Knowledge Graph Enhanced Large Model for Wind-turbine Faults Open
View article: Sono-Gas-Mediated Precise Stiffness Remodeling for Triple-Negative Breast Cancer Mechanical Immunotherapy
Sono-Gas-Mediated Precise Stiffness Remodeling for Triple-Negative Breast Cancer Mechanical Immunotherapy Open
Triple-negative breast cancer (TNBC) is a highly invasive cancer, and its poor therapeutic outcomes are often associated with the mechanical properties of the tumor microenvironment, which is characterized by altered extracellular matrix (…
View article: Vacancy-engineered bismuth vanadate for photoelectrocatalytic glycerol oxidation with simultaneous hydrogen production
Vacancy-engineered bismuth vanadate for photoelectrocatalytic glycerol oxidation with simultaneous hydrogen production Open
A defect-engineered BiVO 4 catalyst with oxygen vacancies on an SnO 2 skeleton enhances charge separation, light absorption, and glycerol activation, enabling efficient DHA production under neutral PEC conditions for sustainable biomass va…
View article: Cancer-targeted pro-theranostic bi-metallic organo-coordination nanoparticles
Cancer-targeted pro-theranostic bi-metallic organo-coordination nanoparticles Open
Rationale: Cancer remains a leading cause of mortality, with aggressive, treatment-resistant tumors posing significant challenges. Current combination therapies and imaging approaches often fail due to disparate pharmacokinetics and…
View article: Effects of dietary rumen-protected glucose level and taurine supplementation on weight change and oxidative stress state of yaks after transport
Effects of dietary rumen-protected glucose level and taurine supplementation on weight change and oxidative stress state of yaks after transport Open
Rumen-protected glucose (RPG) and taurine (TAU) are crucial for the nutrition and physiology of ruminants, enhancing production performance and mitigating negative energy balance. This study aimed to assess the impact of RPG levels and TAU…