Tangfeng Lv
YOU?
Author Swipe
View article: Multi-marker GWAS and variant-specific genomic prediction for growth traits in Pacific white shrimp
Multi-marker GWAS and variant-specific genomic prediction for growth traits in Pacific white shrimp Open
The genome of Penaeus vannamei is rich in short tandem repeats (STRs), occupying 18.96% of the genome, with 68.6% of loci showing high polymorphic information content, highlighting their potential as molecular markers. Accordingly, we perf…
View article: The granulomatous pulmonary nodules induced by tislelizumab in advanced squamous NSCLC: a case report with challenging differential diagnosis
The granulomatous pulmonary nodules induced by tislelizumab in advanced squamous NSCLC: a case report with challenging differential diagnosis Open
This case highlights the diagnostic complexity of ICI-induced granulomatous lung lesions, their steroid responsiveness, and the feasibility of ICIs rechallenge under close monitoring. Pathological confirmation is crucial for the diagnosis,…
View article: Screening of a Gossypol-Removing Yeast Strain and Characterization of Its Removal Mechanism
Screening of a Gossypol-Removing Yeast Strain and Characterization of Its Removal Mechanism Open
Gossypol, a polyphenolic naphthalene derivative and yellow polyphenolic pigment found in cotton seed glands, presents notable environmental, animal, and human health hazards. To screen for yeast strains capable of utilizing gossypol and to…
View article: Expert Consensus on the Diagnosis and Treatment of Malignant Mesothelioma of the Tunica Vaginalis Testis
Expert Consensus on the Diagnosis and Treatment of Malignant Mesothelioma of the Tunica Vaginalis Testis Open
Malignant mesothelioma of the tunica vaginalis testis (MMTVT) is a rare malignancy originating from mesothelial cells of the testicular tunica vaginalis. Due to its insidious onset and local aggressiveness, most patients are diagnosed at a…
View article: Molecular subtyping dictates therapeutic response to anti-PD-L1 immunotherapy in ES-SCLC
Molecular subtyping dictates therapeutic response to anti-PD-L1 immunotherapy in ES-SCLC Open
Anti-PD-L1 immunotherapy is recommended as standard of care for patients with extensive stage small cell lung cancer (ES-SCLC); however, there are no reliable biomarkers guiding patient selection and the survival benefit of PD-L1 inhibitor…
View article: Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion
Intrapleural dual blockade of IL-6 and PD-L1 reprograms CAF dynamics and the tumor microenvironment in lung cancer-associated malignant pleural effusion Open
This study identifies IL-6 as a critical contributor of immune suppression and tumor progression in MPE. The combination of IL-6 and PD-L1 blockade effectively alleviated immunosuppression and reduced tumor burden, offering a potential the…
View article: Combination regimens as potential treatment of non-small-cell lung cancer patients with HER2 mutation in the real world: a multicenter study
Combination regimens as potential treatment of non-small-cell lung cancer patients with HER2 mutation in the real world: a multicenter study Open
Background: Non-small-cell lung cancer (NSCLC) with human epidermal growth factor receptor 2 (HER2) mutations poses significant treatment challenges. While chemotherapy combined with immunotherapy or anti-angiogenic therapy has been explor…
View article: Fast-Flu: RT-RPA-CRISPR/Cas12a assisted one-step platform for rapid influenza B virus detection
Fast-Flu: RT-RPA-CRISPR/Cas12a assisted one-step platform for rapid influenza B virus detection Open
Influenza B virus (Flu B) is a prevalent respiratory pathogen responsible for seasonal influenza epidemics. Despite its clinical significance, there remains a lack of rapid and accurate diagnostic methods for Flu B detection. In this study…
View article: Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma
Expert Consensus on the Diagnosis and Treatment of Malignant Pericardial Mesothelioma Open
Primary malignant pericardial mesothelioma (PMPM), a rare pericardium‐derived malignancy, urgently requires standardized diagnostic and therapeutic protocols. This consensus, established by the Chinese Alliance of Research for Mesothelioma…
View article: Analysis of baseline interstitial lung abnormality on the risk of checkpoint inhibitor-related pneumonitis and survival in advanced non-small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors
Analysis of baseline interstitial lung abnormality on the risk of checkpoint inhibitor-related pneumonitis and survival in advanced non-small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors Open
Pre-existing ILA is an independent risk factor that is strongly associated with CIP, and significantly correlated with worse PFS and OS in advanced NSCLC patients after first-line immunotherapy.
View article: Continuous immunotherapy beyond disease progression in patients with advanced non-small cell and small cell lung cancer
Continuous immunotherapy beyond disease progression in patients with advanced non-small cell and small cell lung cancer Open
Continued immunotherapy as a second-line treatment may benefit patients with driver gene-negative NSCLC and SCLC who have progressed after initial immunotherapy.
View article: Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects
Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects Open
Intrinsic STING of CD8 + T cells affects their function through the HK2/Lactate/IFN-γ axis and affects memory differentiation by regulating glycolysis.
View article: Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development
Emerging roles of mitochondrial sirtuin SIRT5 in succinylation modification and cancer development Open
Succinylation represents an emerging class of post-translational modifications (PTMs), characterized by the enzymatic or non-enzymatic transfer of a negatively charged four-carbon succinyl group to the ϵ-amino group of lysine residues, med…
View article: Inhibitory Effect of Immune Checkpoint Cytotoxic T-Lymphocyte-Associated Antigen-4 Inhibitor Combined with Curcumin on Tumor Growth in Mice with Lung Cancer
Inhibitory Effect of Immune Checkpoint Cytotoxic T-Lymphocyte-Associated Antigen-4 Inhibitor Combined with Curcumin on Tumor Growth in Mice with Lung Cancer Open
We aimed to investigate whether immune checkpoint cytotoxic T-lymphocyteassociated antigen-4 (CTLA-4) inhibitor plus curcumin can inhibit tumor growth in mice with lung cancer. A mouse model of lung cancer was established by injecting Lewi…
View article: Pathologic complete response to pralsetinib in stage IV RET-positive non-small cell lung cancer: A case report
Pathologic complete response to pralsetinib in stage IV RET-positive non-small cell lung cancer: A case report Open
Neoadjuvant therapy with tyrosine kinase inhibitors has been proposed as a feasible approach for downstaging potential resectable non-small cell lung cancer (NSCLC). Pralsetinib is a paradigm of precision medicine for cancers driven by mut…
View article: Comparison of antifungal drugs in the treatment of invasive pulmonary aspergillosis: a systematic review and network meta-analysis
Comparison of antifungal drugs in the treatment of invasive pulmonary aspergillosis: a systematic review and network meta-analysis Open
Background Voriconazole, isavuconazole, and amphotericin (AmB) formulations are currently recommended to treat invasive pulmonary aspergillosis (IPA). We aimed to estimate the efficacy of different antifungal drugs in the initial treatment…
View article: Radiomicsmetabolic signature profiles for advanced non-small cell lung cancer with chemoimmunotherapy by reflecting biological function and survival
Radiomicsmetabolic signature profiles for advanced non-small cell lung cancer with chemoimmunotherapy by reflecting biological function and survival Open
Our findings proved that PET/CT could reveal survival and tumor heterogeneity in advanced NSCLC patients undergoing chemoimmunotherapy, which might guide the selection of immune-monotherapy for low-risk patients and facilitate the advancem…
View article: First‐line chemoimmunotherapy for patients with small‐cell lung cancer and interstitial lung abnormality: <scp>CIP</scp> risk and prognostic analysis
First‐line chemoimmunotherapy for patients with small‐cell lung cancer and interstitial lung abnormality: <span>CIP</span> risk and prognostic analysis Open
Background Patients with non‐small‐cell lung cancer (NSCLC) receiving immunotherapy face a potential risk of developing checkpoint inhibitor‐related pneumonitis (CIP). However, there is no clear understanding of the specific link between i…