Tania Aerts
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View article: Altered socio-affective communication and amygdala development in mice with protocadherin10-deficient interneurons
Altered socio-affective communication and amygdala development in mice with protocadherin10-deficient interneurons Open
Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions associated with deficits in social interaction and communication, together with repetitive behaviours. The cell adhesion molecule protocadherin10 ( PCDH10 ) is link…
View article: Altered Socio-Affective Communication and Amygdala Development in mice with Protocadherin10-deficient Interneurons
Altered Socio-Affective Communication and Amygdala Development in mice with Protocadherin10-deficient Interneurons Open
Autism Spectrum Disorder (ASD) is a group of neurodevelopmental conditions associated with deficits in social interaction and communication, together with repetitive behaviors. The cell adhesion molecule Protocadherin10 ( Pcdh10 ) has been…
View article: Modifying PCDH19 levels affects cortical interneuron migration
Modifying PCDH19 levels affects cortical interneuron migration Open
PCDH19 is a transmembrane protein and member of the protocadherin family. It is encoded by the X-chromosome and more than 200 mutations have been linked to the neurodevelopmental PCDH-clustering epilepsy (PCDH19-CE) syndrome. A disturbed c…
View article: Novel Perspectives on the Development of the Amygdala in Rodents
Novel Perspectives on the Development of the Amygdala in Rodents Open
The amygdala is a hyperspecialized brain region composed of strongly inter- and intraconnected nuclei involved in emotional learning and behavior. The cellular heterogeneity of the amygdalar nuclei has complicated straightforward conclusio…
View article: Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration
Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration Open
Down Syndrome (DS) Cell Adhesion Molecules (DSCAMs) are transmembrane proteins of the immunoglobulin superfamily. Human DSCAM is located within the DS critical region of chromosome 21 (duplicated in Down Syndrome patients), and mutations o…
View article: Protocadherins at the Crossroad of Signaling Pathways
Protocadherins at the Crossroad of Signaling Pathways Open
Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) in vertebrates. In this review, we summarize their discovery, expressi…