Tanja Šobot
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View article: High-Sensitivity Troponins and Homocysteine: Combined Biomarkers for Better Prediction of Cardiovascular Events
High-Sensitivity Troponins and Homocysteine: Combined Biomarkers for Better Prediction of Cardiovascular Events Open
As the leading cause of global mortality, cardiovascular diseases demand improved and innovative strategies for early detection and risk assessment to enhance prevention and timely treatment. This comprehensive review examines the potentia…
Pyridostigmine Treatment Significantly Alleviates Isoprenaline-Induced Chronic Heart Failure in Rats. Open
Autonomic imbalance is one of the major pathological disturbances in chronic heart failure (CHF). Additionally, enhanced oxidative stress and inflammation are considered to be the main contributors to the disease progression. A growing bod…
Liraglutide Treatment Restores Cardiac Function After Isoprenaline-Induced Myocardial Injury and Prevents Heart Failure in Rats Open
Background: Myocardial injury (MI) is characterized by an increased level of at least one cardiac troponin. Experimental MI can be induced by isoprenaline, a β-adrenergic agonist, and it can lead to heart failure (HF). Liraglutide is gluca…
Liraglutide Protects Cardiomyocytes against Isoprenaline-Induced Apoptosis in Experimental Takotsubo Syndrome Open
Takotsubo syndrome (TTS) is a stress-induced cardiomyopathy, characterized by an increased concentration of catecholamines, free radicals, and inflammatory cytokines, endothelial dysfunction, and increased apoptotic activity. High doses of…
Pomegranate Peel Extract Attenuates Isoprenaline-Induced Takotsubo-like Myocardial Injury in Rats Open
Takotsubo syndrome (TTS) is an acute heart failure syndrome characterised by catecholamine-induced oxidative tissue damage. Punica granatum, a fruit-bearing tree, is known to have high polyphenolic content and has been proven to be a poten…
Antioxidative potential of pomegranate peel extract: In vitro and in vivo studies Open
Background/Aim: Due to the numerous beneficial effects of pomegranate that can be explained through its antioxidative effects, the aim of this study was to determine the antioxidant potential of pomegranate peel extract (PoPEx) prepared fr…
Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure—How Strong Is That Link? Open
Cardiovascular diseases are the leading cause of death and the main cause of disability. In the last decade, homocysteine has been found to be a risk factor or a marker for cardiovascular diseases, including myocardial infarction (MI) and …
Major adverse cardiovascular events after implantation of absorb bioresorbable scaffold: One-year clinical outcomes Open
Background/Aim: Bioresorbable vascular scaffold (BVS) represents a novel generation of intracoronary devices designed to be fully resorbed after healing of the stented lesion, delivering antiproliferative drug to suppress restenosis, provi…
Effects of Sulfur Amino Acids on Cardiodynamic Parameters of Isolated Rat Heart Open
Sulfur-containing amino acids are integral part of molecular mechanisms which underlie many aspects of cellular function and homeostasis, facilitated by reversible changes in oxidation states of sulfur atoms. Dysregulation of these pathway…
THE EFFECTS OF SULFUR-CONTAINING COMPOUNDS ON REDOX STATUS IN HOMOCYSTEINE-TREATED RATS Open
There is growing interest in the activity of sulfur-containing compounds on redox balance in physiological and pathological conditions, considering that some of these compounds have not only antioxidative but also pro-oxidative activities.…
Protective Effects of<i>Galium verum L.</i>Extract against Cardiac Ischemia/Reperfusion Injury in Spontaneously Hypertensive Rats Open
Galium verum L . ( G . verum , lady’s bedstraw ) is a perennial herbaceous plant, belonging to the Rubiaceae family. It has been widely used throughout history due to multiple therapeutic properties. However, the effects of this plant spec…
Effect of type of sport, weekly physical exertion and body mass index on values of bone turnover markers in elite female athletes Open
Introduction. The aim of the study was to determine the level of bone turnover markers (serum middle fragment of osteocalcin and b-CrossLaps) in young female athletes involved in different sports, as well as to determine the relation betwe…
BODY COMPOSITION, EATING HABITS AND RISK FACTORS FOR THE DEVELOPMENT OF EATING DISORDER IN FEMALE ELITE ATHLETES Open
The number of women who actively participate in sports has drastically increased in the last few decades, which is a trend followed by many health benefits and serious harmful health side effects as well. The Female Athlete Triad stands ou…