Tarcyane Barata Garcia
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View article: Clinical and economic burden associated with symptomatic and asymptomatic obstructive hypertrophic cardiomyopathy in Germany
Clinical and economic burden associated with symptomatic and asymptomatic obstructive hypertrophic cardiomyopathy in Germany Open
Background The clinical and economic burden of obstructive hypertrophic cardiomyopathy (HCM) in Germany for symptomatic versus asymptomatic patients has not been comprehensively assessed. Methods This retrospective observational study anal…
View article: Flexible, integrated, and person-centered psychiatric care through global treatment budgets: results of the multiperspective study PsychCare
Flexible, integrated, and person-centered psychiatric care through global treatment budgets: results of the multiperspective study PsychCare Open
Background To overcome fragmented care provision in Germany, flexible, integrated psychiatric care (FIT) model projects according to § 64b of the German Social Code Book (SGB) V were implemented. Objectives The results of the prospective c…
View article: Epidemiology, disease burden and costs of Duchenne muscular dystrophy in Germany: an observational, retrospective health claims data analysis
Epidemiology, disease burden and costs of Duchenne muscular dystrophy in Germany: an observational, retrospective health claims data analysis Open
Background Duchenne muscular dystrophy (DMD) is a rare genetic disorder that primarily affects males. Beginning in childhood, patients experience ambulatory loss, heart failure and need ventilation. Disease management has improved, however…
View article: Real-World Prevalence, Incidence and Management of Systemic Lupus Erythematosus in Germany: A Retrospective Claims Data Analysis
Real-World Prevalence, Incidence and Management of Systemic Lupus Erythematosus in Germany: A Retrospective Claims Data Analysis Open
Our data demonstrate an increased prevalence of SLE with stable incidence in Germany, suggesting improved survival of affected patients. Nevertheless, suboptimal treatment patterns, including limited use of biologics, reflect a high unmet …
View article: Relationship of proteins and subclinical cardiovascular traits in the population-based LIFE-Adult study
Relationship of proteins and subclinical cardiovascular traits in the population-based LIFE-Adult study Open
We extend the catalogue of proteome biomarkers possibly involved in early stages of cardiovascular disease pathologies providing targets for early risk prediction or intervention strategies.
View article: Agreement between self-reports and statutory health insurance claims data on healthcare utilization in patients with mental disorders
Agreement between self-reports and statutory health insurance claims data on healthcare utilization in patients with mental disorders Open
View article: Self-reported versus administrative data records: implications for assessing healthcare resource utilization of mental disorders
Self-reported versus administrative data records: implications for assessing healthcare resource utilization of mental disorders Open
Background : Data on resourceuse are frequently required for health economic evaluation. Studies on health care utilization in individuals with mental disorders have analyzed both self-reports and administrative data, each of which with st…
View article: Genetically regulated gene expression and proteins revealed discordant effects
Genetically regulated gene expression and proteins revealed discordant effects Open
Background Although gene-expression (GE) and protein levels are typically strongly genetically regulated, their correlation is known to be low. Here we investigate this phenomenon by focusing on the genetic background of this correlation i…
View article: Local inhibition of nitrergic activity in tenotomized rats accelerates muscle regeneration by increasing fiber area and decreasing central core lesions
Local inhibition of nitrergic activity in tenotomized rats accelerates muscle regeneration by increasing fiber area and decreasing central core lesions Open
Muscular atrophy is a progressive degeneration characterized by muscular proteolysis, loss of mass and decrease in fiber area. Tendon rupture induces muscular atrophy due to an intrinsic functional connection. Local inhibition of nitric ox…
View article: Local inhibition of nitrergic activity in tenotomized rats accelerates muscle regeneration by increasing fiber area and decreasing central core lesions
Local inhibition of nitrergic activity in tenotomized rats accelerates muscle regeneration by increasing fiber area and decreasing central core lesions Open
Muscular atrophy is a progressive degeneration characterized by muscular proteolysis, loss of mass and decrease in fiber area. Tendon rupture induces muscular atrophy due to an intrinsic functional connection. Local inhibition of nitric ox…
View article: Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5
Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5 Open