Tarek Saba
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View article: Point-of-Care Disease Screening in Primary Care Using Saliva: A Biospectroscopy Approach for Lung Cancer and Prostate Cancer
Point-of-Care Disease Screening in Primary Care Using Saliva: A Biospectroscopy Approach for Lung Cancer and Prostate Cancer Open
Saliva is a largely unexplored liquid biopsy that can be readily obtained noninvasively. Not dissimilar to blood plasma or serum, it contains a vast array of bioconstituents that may be associated with the absence or presence of a disease …
View article: Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial—MIST-3
Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial—MIST-3 Open
Rationale: Assessing the early use of video-assisted thoracoscopic surgery (VATS) or intrapleural enzyme therapy (IET) in pleural infection requires a phase III randomized controlled trial (RCT). Objectives: To establish the …
View article: ATR-FTIR Spectroscopy with Chemometrics for Analysis of Saliva Samples Obtained in a Lung-Cancer-Screening Programme: Application of Swabs as a Paradigm for High Throughput in a Clinical Setting
ATR-FTIR Spectroscopy with Chemometrics for Analysis of Saliva Samples Obtained in a Lung-Cancer-Screening Programme: Application of Swabs as a Paradigm for High Throughput in a Clinical Setting Open
There is an increasing need for inexpensive and rapid screening tests in point-of-care clinical oncology settings. Herein, we develop a swab “dip” test in saliva obtained from consenting patients participating in a lung-cancer-screening pr…
View article: P398 Using the science of health care improvement to implement a virtual cystic fibrosis service post COVID-19 pandemic
P398 Using the science of health care improvement to implement a virtual cystic fibrosis service post COVID-19 pandemic Open
View article: A randomised controlled trial of intrapleural balloon intercostal chest drains to prevent drain displacement
A randomised controlled trial of intrapleural balloon intercostal chest drains to prevent drain displacement Open
Background Chest drain displacement is a common clinical problem that occurs in 9–42% of cases and results in treatment failure or additional pleural procedures conferring unnecessary risk. A novel chest drain with an integrated intrapleur…
View article: Continuous positive airway pressure (CPAP) as a ceiling of care treatment for hypoxaemic respiratory failure due to COVID-19
Continuous positive airway pressure (CPAP) as a ceiling of care treatment for hypoxaemic respiratory failure due to COVID-19 Open
COVID-19 causes a wide spectrum of disease, which at its most severe can lead to hypoxaemic respiratory failure necessitating respiratory support. While guidelines recommend CPAP as a treatment option for such patients, including those for…
View article: Continuous positive airway pressure (CPAP) as a ceiling of care treatment for hypoxemic respiratory failure due to COVID-19
Continuous positive airway pressure (CPAP) as a ceiling of care treatment for hypoxemic respiratory failure due to COVID-19 Open
View article: P231 Patient experience of accessing a virtual cystic fibrosis service during the 2020 SARS-CoV-2 pandemic in Blackpool, North West of England
P231 Patient experience of accessing a virtual cystic fibrosis service during the 2020 SARS-CoV-2 pandemic in Blackpool, North West of England Open
View article: Pulmonary passport: a service evaluation study of a standardised web-based procedure logbook to aid specialist respiratory training and appraisal
Pulmonary passport: a service evaluation study of a standardised web-based procedure logbook to aid specialist respiratory training and appraisal Open
Introduction The pulmonary passport (PP) is a secure web-based procedural logbook for specialist respiratory trainees with enhanced functionality that includes automated analysis to provide key performance metrics and in-platform interacti…
View article: Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study
Prospective validation of the RAPID clinical risk prediction score in adult patients with pleural infection: the PILOT study Open
Background Over 30% of adult patients with pleural infection either die and/or require surgery. There is no robust means of predicting at baseline presentation which patients will suffer a poor clinical outcome. A validated risk prediction…
View article: Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion
Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion Open
Among patients without substantial lung entrapment, the outpatient administration of talc through an indwelling pleural catheter for the treatment of malignant pleural effusion resulted in a significantly higher chance of pleurodesis at 35…
View article: Prospective Validation of The RAPID Clinical Risk Prediction Score in Patients with Pleural Infection: The Pleural Infection Longitudinal Outcome Study (PILOT)
Prospective Validation of The RAPID Clinical Risk Prediction Score in Patients with Pleural Infection: The Pleural Infection Longitudinal Outcome Study (PILOT) Open
View article: S128 Exploring the behaviour of mesothelioma in a post hoc analysis from the time 1 trial
S128 Exploring the behaviour of mesothelioma in a post hoc analysis from the time 1 trial Open
Introduction Malignant Pleural Mesothelioma (MPM) is the only malignancy which develops primarily in the pleural space and is a common cause of a malignant pleural effusion (MPE). MPE associated with MPM is managed similarly to any other m…
View article: S129 Does inflammation predict successful pleurodesis? a post hoc analysis from the time 1 trial
S129 Does inflammation predict successful pleurodesis? a post hoc analysis from the time 1 trial Open
Introduction Malignant pleural effusions are a common complication of advanced malignancy, have a poor prognosis and have a significant impact on quality of life. Treatment strategies include chest drain and pleurodesis, or insertion of an…
View article: S20 Primary Result of the 1st Therapeutic Interventions in Malignant Effusion (TIME1) Trial: A 2 × 2 factorial, randomised trial of chest tube size and analgesic strategy for pleurodesis in malignant pleural effusion
S20 Primary Result of the 1st Therapeutic Interventions in Malignant Effusion (TIME1) Trial: A 2 × 2 factorial, randomised trial of chest tube size and analgesic strategy for pleurodesis in malignant pleural effusion Open
Background Optimal management of pleurodesis for malignant pleural effusion (MPE) has not been defined either in terms of optimal analgesia or chest tube size. Non-steroidal anti-inflammatory drugs (NSAID) are highly effective analgesics, …