Taryn E. Keyzer
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Stem cell-derived brain-like endothelial cells to interrogate <i>Streptococcus pneumoniae</i> interaction with brain endothelium Open
Streptococcus pneumoniae (pneumococcus) is an opportunistic pathogen that remains the leading cause of bacterial meningitis worldwide. For meningitis to occur, pneumococcus must breach the blood-brain barrier (BBB), a highly specialized ne…
Transcriptome of brain-like endothelial cells following coxsackievirus B3 infection Open
Coxsackievirus B3 is a leading cause of viral aseptic meningitis. To gain entry to the central nervous system, it must interact with and disrupt the brain endothelial cells of the blood-brain barrier. Here, we report the global transcripto…
View article: Transcriptomic analysis of coxsackievirus B3 infection in induced pluripotent stem cell-derived brain-like endothelial cells
Transcriptomic analysis of coxsackievirus B3 infection in induced pluripotent stem cell-derived brain-like endothelial cells Open
Viral aseptic meningitis is a neuroinflammatory condition that occurs when viruses gain access to the central nervous system (CNS) and induce inflammation. The blood–brain barrier (BBB) is comprised of brain endothelial cells (BECs) that s…
Common Chemical Plasticizer Di(2-Ethhylhexyl) Phthalate Exposure Exacerbates Coxsackievirus B3 Infection Open
Di(2-ethhylhexyl) phthalate (DEHP) is a common plastic rubberizer. DEHP leaches from plastic matrices and is under increasing scrutiny as numerous studies have linked it to negative human health manifestations. Coxsackievirus B3 (CVB) is a…
Common Chemical Plasticizer di(2-Ethhylhexyl) Phthalate Exposure Exacerbates Coxsackievirus B3 Infection Open
Di(2-ethhylhexyl) phthalate (DEHP) is a common plastic rubberizer. DEHP leaches from plastic matrices and is under increasing scrutiny as numerous studies have linked it to negative human health manifestations. Coxsackievirus B3 (CVB) is a…