Tasneem Yusufali
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View article: A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection
A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection Open
Studies have demonstrated that at least 20% of individuals infected with SARS-CoV-2 remain asymptomatic 1–4 . Although most global efforts have focused on severe illness in COVID-19, examining asymptomatic infection provides a unique oppor…
View article: Minimal observed impact of <scp>HLA</scp> genotype on hospitalization and severity of <scp>SARS‐CoV</scp> ‐2 infection
Minimal observed impact of <span>HLA</span> genotype on hospitalization and severity of <span>SARS‐CoV</span> ‐2 infection Open
HLA is a critical component of the viral antigen presentation pathway. We investigated the relationship between the severity of SARS‐CoV‐2 disease and HLA type in 3235 individuals with confirmed SARS‐CoV‐2 infection. We found only the DPB1…
View article: Minimal observed impact of HLA genotype on hospitalization and severity of SARS-CoV-2 infection
Minimal observed impact of HLA genotype on hospitalization and severity of SARS-CoV-2 infection Open
HLA is a critical component of the viral antigen presentation pathway. We investigated the relationship between severity of SARS-CoV-2 disease and HLA type in 3,235 individuals with confirmed SARS-CoV-2 infection. We found only the DPB1 lo…
View article: High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING
High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING Open
The killer-cell immunoglobulin-like receptor ( KIR) complex on chromosome 19 encodes receptors that modulate the activity of natural killer cells, and variation in these genes has been linked to infectious and autoimmune disease, as well a…
View article: A common allele of HLA mediates asymptomatic SARS-CoV-2 infection
A common allele of HLA mediates asymptomatic SARS-CoV-2 infection Open
Despite some inconsistent reporting of symptoms, studies have demonstrated that at least 20% of individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will remain asymptomatic. Although most global efforts h…
View article: High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING
High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING Open
The killer-cell immunoglobulin-like receptor ( KIR) complex on chromosome 19 encodes receptors that modulate the activity of natural killer cells, and variation in these genes has been linked to infectious and autoimmune disease, as well a…
View article: Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease
Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease Open
Immune dysfunction plays a role in the development of Parkinson disease (PD). NK cells regulate immune functions and are modulated by killer cell immunoglobulin-like receptors (KIR). KIR are expressed on the surface of NK cells and interac…