Tatsuo Aoki
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View article: Effect of exercise training in patients with cardiac sarcoidosis after induction of oral corticosteroid therapy.
Effect of exercise training in patients with cardiac sarcoidosis after induction of oral corticosteroid therapy. Open
Patients with CS treated with 30 mg/day prednisolone showed poor QIS early in the corticosteroid induction period, even with ET. Patients with CS who receive corticosteroids may be more susceptible to developing corticosteroid myopathy.
View article: Clinical impact of mean pulmonary arterial pressure after balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension
Clinical impact of mean pulmonary arterial pressure after balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension Open
Background Balloon pulmonary angioplasty (BPA) improves haemodynamics in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). Previous studies on BPA have set the treatment objective to achieve a mean pulmonary a…
View article: Prevalence and Clinical Characteristics of Heterozygous <i>RNF213 p.Arg4810Lys</i> Variant Carriers Diagnosed With Chronic Thromboembolic Pulmonary Hypertension
Prevalence and Clinical Characteristics of Heterozygous <i>RNF213 p.Arg4810Lys</i> Variant Carriers Diagnosed With Chronic Thromboembolic Pulmonary Hypertension Open
Background Ring finger protein 213 ( RNF213 ) p.Arg4810Lys is a susceptibility gene for moyamoya disease, peripheral pulmonary artery stenosis (PPS), and other vascular diseases and thrombosis. We investigated the prevalence and clinical c…
View article: Effect of direct oral anticoagulant therapy on pulmonary artery clot dissolution in intermediate high-risk pulmonary thromboembolism
Effect of direct oral anticoagulant therapy on pulmonary artery clot dissolution in intermediate high-risk pulmonary thromboembolism Open
View article: Balloon pulmonary angioplasty for chronic thromboembolic pulmonary disease without pulmonary hypertension
Balloon pulmonary angioplasty for chronic thromboembolic pulmonary disease without pulmonary hypertension Open
Balloon pulmonary angioplasty (BPA) is beneficial for patients with chronic thromboembolic pulmonary disease (CTEPD) with pulmonary hypertension (PH). However, the clinical benefit of BPA for the patients with CTEPD without PH remains unkn…
View article: Clinical outcomes of upfront combination therapy for portopulmonary hypertension
Clinical outcomes of upfront combination therapy for portopulmonary hypertension Open
View article: Calcium channel blockers in patients with pulmonary arterial hypertension receiving PAH-specific treatment
Calcium channel blockers in patients with pulmonary arterial hypertension receiving PAH-specific treatment Open
CCB therapy benefited patients with IPAH who showed acute response to vasoreactivity testing using inhaled NO, even when receiving modern PAH-specific therapy. Acute vasoreactive responders may benefit more from CCB than from PAH-specific …
View article: Clinical impact of residual pulmonary hypertension based on revised criteria after balloon pulmonary angioplasty
Clinical impact of residual pulmonary hypertension based on revised criteria after balloon pulmonary angioplasty Open
Background Balloon pulmonary angioplasty (BPA) improves haemodynamics, exercise capacity, and prognosis in patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH). However, the treatment goal of BPA is not well estab…
View article: Inhaled nitric oxide testing in predicting prognosis in pulmonary hypertension due to left‐sided heart diseases
Inhaled nitric oxide testing in predicting prognosis in pulmonary hypertension due to left‐sided heart diseases Open
Aims The pathophysiology of pulmonary hypertension (PH) due to left‐sided heart disease (Group 2 PH) is distinct from that of other groups of PH, yet there are still no approved therapies that selectively target pulmonary circulation. The …
View article: Pulmonary arterial hypertension sensitive to calcium channel blocker, but not advanced pulmonary hypertension treatment: a case report
Pulmonary arterial hypertension sensitive to calcium channel blocker, but not advanced pulmonary hypertension treatment: a case report Open
Background Calcium channel blockers (CCB), the first accepted treatment, is effective only in a small number of idiopathic pulmonary arterial hypertension (I-PAH) patients with vasoreactivity [these patients are identified by a positive ac…
View article: Prognostic impact of follow-up pulmonary vascular resistance in pulmonary arterial hypertension
Prognostic impact of follow-up pulmonary vascular resistance in pulmonary arterial hypertension Open
Objective Pulmonary arterial hypertension (PAH), caused by pulmonary artery remodelling and increased pulmonary vascular resistance (PVR) due to an unknown mechanism, is an intractable disease with a poor prognosis. The recent development …
View article: C65 POST–DISCHARGE ARRHYTHMIC RISK STRATIFICATION OF PATIENTS WITH ACUTE MYOCARDITIS AND LIFE–THREATENING VENTRICULAR TACHYARRHYTHMIAS
C65 POST–DISCHARGE ARRHYTHMIC RISK STRATIFICATION OF PATIENTS WITH ACUTE MYOCARDITIS AND LIFE–THREATENING VENTRICULAR TACHYARRHYTHMIAS Open
Aims The outcomes of patients presenting with acute myocarditis and life–threatening ventricular arrhythmias (LT–VA) are unclear. The aim of this study was to assess the incidence and predictors of recurrent major arrhythmic events (MAEs) …
View article: Systemic-pulmonary collateral supply associated with clinical severity of chronic thromboembolic pulmonary hypertension: a study using intra-aortic computed tomography angiography
Systemic-pulmonary collateral supply associated with clinical severity of chronic thromboembolic pulmonary hypertension: a study using intra-aortic computed tomography angiography Open
Objectives To assess whether systemic-pulmonary collaterals are associated with clinical severity and extent of pulmonary perfusion defects in chronic thromboembolic pulmonary hypertension (CTEPH). Methods This prospective study was approv…
View article: Association of adherence to a 3 month cardiac rehabilitation with long‐term clinical outcomes in heart failure patients
Association of adherence to a 3 month cardiac rehabilitation with long‐term clinical outcomes in heart failure patients Open
Aims Although comprehensive cardiac rehabilitation (CCR) is recommended for patients with heart failure (HF), participants often show low adherence. The aim of this study was to evaluate the association of CCR completion and response with …
View article: Quantification of vortex flow in pulmonary arteries of patients with chronic thromboembolic pulmonary hypertension
Quantification of vortex flow in pulmonary arteries of patients with chronic thromboembolic pulmonary hypertension Open
BPA promoted significant decreases in the FWHM, area, and VFR of backward flow in the pulmonary trunk, thereby facilitating efficient blood transport. The tendencies for these changes were to be larger for cases where BPA more greatly decr…
View article: Prognostic value of right ventricular native T1 mapping in pulmonary arterial hypertension
Prognostic value of right ventricular native T1 mapping in pulmonary arterial hypertension Open
Background Right ventricular function is an important prognostic marker for pulmonary arterial hypertension. Native T1 mapping using cardiovascular magnetic resonance imaging can characterize the myocardium, but accumulating evidence indic…
View article: Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia
Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia Open
Various forms of supraventricular tachycardia (SVT) occur in patients with severe pulmonary hypertension (PH). Despite the high efficacy of radiofrequency catheter ablation (RFCA) for SVT, insufficient data exist regarding patients with PH…
View article: Post‐discharge arrhythmic risk stratification of patients with acute myocarditis and life‐threatening ventricular tachyarrhythmias
Post‐discharge arrhythmic risk stratification of patients with acute myocarditis and life‐threatening ventricular tachyarrhythmias Open
Aims The outcomes of patients presenting with acute myocarditis and life‐threatening ventricular arrhythmias (LT‐VA) are unclear. The aim of this study was to assess the incidence and predictors of recurrent major arrhythmic events (MAEs) …
View article: Quantification of Vortex Flow in Pulmonary Arteries of Patients With Chronic Thromboembolic Pulmonary Hypertension
Quantification of Vortex Flow in Pulmonary Arteries of Patients With Chronic Thromboembolic Pulmonary Hypertension Open
Purpose: This study proposes an objective method of quantifying the vortex flow in pulmonary arteries to compare the duration of its presence before and after balloon pulmonary angioplasty (BPA) in patients with chronic thromboembolic pulm…
View article: Beneficial effects of balloon pulmonary angioplasty on clinical outcomes in patients with residual pulmonary hypertension after pulmonary endarterectomy
Beneficial effects of balloon pulmonary angioplasty on clinical outcomes in patients with residual pulmonary hypertension after pulmonary endarterectomy Open
Background Although pulmonary endarterectomy (PEA) is an established surgical treatment for chronic thromboembolic pulmonary hypertension (CTEPH), a part of patients after PEA show residual pulmonary hypertension, leading to limited exerci…
View article: Identification of the Novel Variants in Patients With Chronic Thromboembolic Pulmonary Hypertension
Identification of the Novel Variants in Patients With Chronic Thromboembolic Pulmonary Hypertension Open
Background Although chronic thromboembolic pulmonary hypertension (CTEPH) and acute pulmonary embolism (APE) share some clinical manifestations, a limited proportion of patients with CTEPH have a history of APE. Moreover, in histopathologi…
View article: Beneficial effects of riociguat on hemodynamic responses to exercise in CTEPH patients after balloon pulmonary angioplasty – A randomized controlled study
Beneficial effects of riociguat on hemodynamic responses to exercise in CTEPH patients after balloon pulmonary angioplasty – A randomized controlled study Open
These results indicate that riociguat exerts beneficial effects on hemodynamic response to exercise in CTEPH patients even after hemodynamic improvement by BPA.
View article: BENEFICIAL EFFECTS OF RIOCIGUAT ON HEMODYNAMIC RESPONSES TO EXERCISE IN CTEPH PATIENTS AFTER BALLOON PULMONARY ANGIOPLASTY: A RANDOMIZED CONTROLLED STUDY
BENEFICIAL EFFECTS OF RIOCIGUAT ON HEMODYNAMIC RESPONSES TO EXERCISE IN CTEPH PATIENTS AFTER BALLOON PULMONARY ANGIOPLASTY: A RANDOMIZED CONTROLLED STUDY Open
View article: Viral genome search in myocardium of patients with fulminant myocarditis
Viral genome search in myocardium of patients with fulminant myocarditis Open
International audience
View article: 4D-flow MRI assessment of blood flow before and after endovascular intervention in a patient with pulmonary hypertension due to isolated pulmonary artery involvement in large vessel vasculitis
4D-flow MRI assessment of blood flow before and after endovascular intervention in a patient with pulmonary hypertension due to isolated pulmonary artery involvement in large vessel vasculitis Open
View article: Identification of Adipsin as a Novel Prognostic Biomarker in Patients With Coronary Artery Disease
Identification of Adipsin as a Novel Prognostic Biomarker in Patients With Coronary Artery Disease Open
Background Circulating proteins are exposed to vascular endothelial layer and influence their functions. Among them, adipsin is a member of the trypsin family of peptidases and is mainly secreted from adipocytes, monocytes, and macrophages…
View article: Prognostic value of the model for end-stage liver disease excluding INR score (MELD-XI) in patients with adult congenital heart disease
Prognostic value of the model for end-stage liver disease excluding INR score (MELD-XI) in patients with adult congenital heart disease Open
Patients with adult congenital heart disease (ACHD) are at increased risk of developing late cardiovascular complication. However, little is known about the predictive factors for long-term outcome. The Model for End-Stage Liver Disease eX…
View article: Cyclophilin A as a biomarker for the therapeutic effect of balloon angioplasty in chronic thromboembolic pulmonary hypertension
Cyclophilin A as a biomarker for the therapeutic effect of balloon angioplasty in chronic thromboembolic pulmonary hypertension Open
View article: Successful Management of Acute Congestive Heart Failure by Emergent Caesarean Section Followed by Adrenalectomy in a Pregnant Woman with Cushing's Syndrome-induced Cardiomyopathy
Successful Management of Acute Congestive Heart Failure by Emergent Caesarean Section Followed by Adrenalectomy in a Pregnant Woman with Cushing's Syndrome-induced Cardiomyopathy Open
Congestive heart failure (CHF) is rare during pregnancy. We herein report a 35-year-old woman who developed CHF with severe left ventricular dysfunction at 35 weeks' gestation. She underwent emergency Caesarean section followed by intensiv…
View article: Usefulness of scoring system for diagnosis of vasospastic angina – Is spasm provocation test no longer needed?
Usefulness of scoring system for diagnosis of vasospastic angina – Is spasm provocation test no longer needed? Open