Taylor Bopp
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View article: Metabolic dysfunction and the development of physical frailty: an aging war of attrition
Metabolic dysfunction and the development of physical frailty: an aging war of attrition Open
View article: Volume loss during muscle reinnervation surgery is correlated with reduced CMAP amplitude but not reduced force output in a rat hindlimb model
Volume loss during muscle reinnervation surgery is correlated with reduced CMAP amplitude but not reduced force output in a rat hindlimb model Open
Introduction: Muscle reinnervation (MR) surgery offers rehabilitative benefits to amputees by taking severely damaged nerves and providing them with new denervated muscle targets (DMTs). However, the influence of physical changes to muscle…
View article: Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model
Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model Open
Chronic activation of inflammatory pathways (CI) and mitochondrial dysfunction are independently linked to age-related functional decline and early mortality. Interleukin 6 (IL-6) is among the most consistently elevated chronic activation …
View article: Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex‐specific pattern
Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex‐specific pattern Open
Decline in neuromuscular function with aging is known to be a major determinant of disability and all‐cause mortality in late life. Despite the importance of the problem, the neurobiology of age‐associated muscle weakness is poorly underst…
View article: Volume Loss During Muscle Reinnervation Surgery Is Correlated With Reduced EMG Signals, but Not Reduced Force Output, in a Rat Hindlimb Model
Volume Loss During Muscle Reinnervation Surgery Is Correlated With Reduced EMG Signals, but Not Reduced Force Output, in a Rat Hindlimb Model Open
View article: <scp>SARM1</scp> knockout does not rescue neuromuscular phenotypes in a <scp>Charcot‐Marie‐Tooth</scp> disease Type <scp>1A</scp> mouse model
<span>SARM1</span> knockout does not rescue neuromuscular phenotypes in a <span>Charcot‐Marie‐Tooth</span> disease Type <span>1A</span> mouse model Open
Charcot‐Marie‐Tooth disease Type 1A (CMT1A) is caused by duplication of the PMP22 gene and is the most common inherited peripheral neuropathy. Although CMT1A is a dysmyelinating peripheral neuropathy, secondary axon degeneration has been s…
View article: New evidence for secondary axonal degeneration in demyelinating neuropathies
New evidence for secondary axonal degeneration in demyelinating neuropathies Open