David McD Taylor
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View article: Patient engagement in research: lessons learned from CAPTURE ALS, a longitudinal observational ALS study
Patient engagement in research: lessons learned from CAPTURE ALS, a longitudinal observational ALS study Open
CAPTURE ALS was shaped by meaningful engagement initiatives over the course of the study. Lessons learned included: begin early and embed PEIR within research; build relationships and foster mutual learning; be flexible, open to adaptation…
View article: Evidence of Electron Heating by Alpha Particles in JET Deuterium-Tritium Plasmas
Evidence of Electron Heating by Alpha Particles in JET Deuterium-Tritium Plasmas Open
The fusion-born alpha particle heating in magnetically confined fusion machines is a high priority subject for studies. The self-heating of thermonuclear fusion plasma by alpha particles was observed in recent deuterium-tritium (D-T) exper…
View article: Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis
Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis Open
Purpose To investigate the effect of IV fluid resuscitation on endothelial glycocalyx (EG) shedding and activation of the vascular endothelium and inflammation. Materials and methods A planned biomarker sub-study of the REFRESH trial in wh…
View article: Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest
Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest Open
Importance The administration of a high fraction of oxygen following return of spontaneous circulation in out-of-hospital cardiac arrest may increase reperfusion brain injury. Objective To determine whether targeting a lower oxygen saturat…
View article: Development of Screening Tools to Predict Medication-Related Problems Across the Continuum of Emergency Department Care: A Prospective, Multicenter Study
Development of Screening Tools to Predict Medication-Related Problems Across the Continuum of Emergency Department Care: A Prospective, Multicenter Study Open
Background: Medication-related problems (MRPs) occur across the continuum of emergency department (ED) care: they may contribute to ED presentation, occur in the ED/short-stay unit (SSU), at hospital admission, or shortly after discharge t…
View article: Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis
Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis Open
INTRODUCTIONIntravenous (IV) fluid resuscitation is recommended first line therapy in septic shock, but the effectiveness and safety of this approach has been questioned. To investigate potential mechanisms of harm from IV fluid resuscitat…
View article: Medication not accounted for in hospital electronic medication administration records: a retrospective observational study
Medication not accounted for in hospital electronic medication administration records: a retrospective observational study Open
Substantial quantities of medications supplied to hospital wards and EDs are not accounted for in electronic administration records.
View article: Relation of substance use disorders to mortality, accident and emergency department attendances, and hospital admissions: A 13-year population-based cohort study in Hong Kong
Relation of substance use disorders to mortality, accident and emergency department attendances, and hospital admissions: A 13-year population-based cohort study in Hong Kong Open
SUD was associated with increased mortality, A&E attendances and hospital admissions, especially in school-aged individuals. Our findings suggest prioritising early treatment and preventive interventions for school-aged individuals and foc…
View article: Regular medication use by active scuba divers with a declared comorbid medical condition and victims of scuba and snorkelling-related fatalities
Regular medication use by active scuba divers with a declared comorbid medical condition and victims of scuba and snorkelling-related fatalities Open
Introduction: The aim of this study was to describe the nature of regular medications taken by active comorbid scuba divers (having a declared medical comorbidity) and scuba divers and snorkellers who died following a diving incident. Meth…
View article: The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain
The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain Open
Australian New Zealand Clinical Trials Registry, ACTRN12618000487213 (prospective).
View article: A prospective, randomized, double‐blind trial of intravenous chlorpromazine versus intravenous prochlorperazine for the treatment of acute migraine in adults presenting to the emergency department
A prospective, randomized, double‐blind trial of intravenous chlorpromazine versus intravenous prochlorperazine for the treatment of acute migraine in adults presenting to the emergency department Open
Objective To compare the efficacy of intravenous chlorpromazine versus intravenous prochlorperazine for the treatment of acute migraine in adults presenting to the emergency department (ED). Background Migraine is a common, incapacitating …
View article: Discordance between patient‐reported and actual emergency department pain management
Discordance between patient‐reported and actual emergency department pain management Open
Objective To determine patient knowledge of the nature of their pain management in the ED. Methods This was a planned sub‐study of data collected during a randomised, controlled trial of the nature of the informed consent process in a sing…
View article: Prognostic performance of qSOFA in oncology patients admitted to the emergency department with suspected infection
Prognostic performance of qSOFA in oncology patients admitted to the emergency department with suspected infection Open
Aim We aimed to test the performance of the quick Sequential Organ Failure Assessment score (qSOFA) in predicting the outcomes of oncology patients admitted to the emergency department (ED) with suspected infection. Methods Retrospective c…
View article: Scuba diving fatalities in Australia 2001 to 2013: Chain of events
Scuba diving fatalities in Australia 2001 to 2013: Chain of events Open
Introduction: We aimed to identify the possible chain of events leading to fatal scuba diving incidents in Australia from 2001–2013 to inform appropriate countermeasures. Methods: The National Coronial Information System was searched to id…
View article: Outcomes of laceration suture repair in the emergency department
Outcomes of laceration suture repair in the emergency department Open
Objective To assess patient satisfaction with laceration management, post‐ED care, cosmesis and complication rates. Methods We undertook a prospective observational study of adult patients with lacerations sutured in two EDs over a 4‐month…
View article: Scuba diving fatalities in Australia, 2001 to 2013: Diver demographics and characteristics
Scuba diving fatalities in Australia, 2001 to 2013: Diver demographics and characteristics Open
Introduction: This study identified characteristics of victims of fatal scuba diving incidents to determine contributing factors and inform appropriate countermeasures. Methods: The National Coronial Information System (NCIS) was searched …
View article: Medical conditions in scuba diving fatality victims in Australia, 2001 to 2013
Medical conditions in scuba diving fatality victims in Australia, 2001 to 2013 Open
Introduction: This study identified pre-existing medical conditions among scuba diving fatalities in Australia from 2001 to 2013, inclusive, and assessed whether these conditions likely contributed to the deaths. Methods: The National Coro…
View article: The Australasian Resuscitation In Sepsis Evaluation: Fluids or vasopressors in emergency department sepsis (ARISE FLUIDS), a multi‐centre observational study describing current practice in Australia and New Zealand
The Australasian Resuscitation In Sepsis Evaluation: Fluids or vasopressors in emergency department sepsis (ARISE FLUIDS), a multi‐centre observational study describing current practice in Australia and New Zealand Open
Objectives To describe haemodynamic resuscitation practices in ED patients with suspected sepsis and hypotension. Methods This was a prospective, multicentre, observational study conducted in 70 hospitals in Australia and New Zealand betwe…
View article: Patient perceptions of participation in emergency medicine research projects
Patient perceptions of participation in emergency medicine research projects Open
Objective To determine if ED research reflects patient expectations. Method A cross‐sectional ED patient survey. Results Three hundred and nine (98.1%, 95% confidence interval [CI] 95.7–99.2) of 315 patients believed that ED research was i…
View article: Comprehensive identification of medication‐related problems occurring prior to, during and after emergency department presentation: An Australian multicentre, prospective, observational study
Comprehensive identification of medication‐related problems occurring prior to, during and after emergency department presentation: An Australian multicentre, prospective, observational study Open
Objective Patients present to EDs with various medication‐related problems (MRPs). MRPs are also associated with ED care, occurring during ED presentation or shortly afterwards. The aim of the present study is to describe the prevalence an…
View article: Basic statistics: A research primer for low- and middle-income countries
Basic statistics: A research primer for low- and middle-income countries Open
Statistics can be used to describe data or make inferences about populations using samples. Median values (the 50th percentile) better represent central tendency of data samples than means (averages), particularly when data have extreme va…
View article: Conference presentations: A research primer for low- and middle-income countries
Conference presentations: A research primer for low- and middle-income countries Open
Presenting research at a conference is an opportunity to disseminate the findings, network with other researchers, and to develop your academic track record. Although every conference will have some local differences, there are common appr…
View article: Risk variables associated with abnormal calcium, magnesium and phosphate levels among emergency department patients
Risk variables associated with abnormal calcium, magnesium and phosphate levels among emergency department patients Open
Objective The utility of calcium, magnesium and phosphate measurement in the ED is limited. We aimed to determine clinical risk variables for abnormal levels of these electrolytes in order to inform the development of an ordering guideline…
View article: Glenoid vault perforation in total shoulder arthroplasty: Do we need computer guidance?
Glenoid vault perforation in total shoulder arthroplasty: Do we need computer guidance? Open
The proliferation of computer 3D simulation and computer-generated guides is aimed at minimizing perforation of the glenoid vault by glenoid pegs in shoulder arthroplasty, based on assumptions that perforation leads to worse outcomes by co…
View article: Management of behavioural emergencies: a prospective observational study in Australian emergency departments
Management of behavioural emergencies: a prospective observational study in Australian emergency departments Open
Background Behavioural emergencies (BEs) are complex situations in the emergency department (ED) setting. Treatment decisions always must be made within a limited time and are based on incomplete patient data. As a result of the urgency an…
View article: Risk Factors for Sedation‐related Events During Acute Agitation Management in the Emergency Department
Risk Factors for Sedation‐related Events During Acute Agitation Management in the Emergency Department Open
Objective The objective was to describe the incidence, nature, and risk factors for adverse events ( AE s) among patients who received parenteral sedation for acute agitation in an emergency department ( ED ) setting. Methods We undertook …