Taylor Wintler
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View article: Transcriptional dynamics of sleep deprivation and subsequent recovery sleep in the male mouse cortex
Transcriptional dynamics of sleep deprivation and subsequent recovery sleep in the male mouse cortex Open
This study investigates different time points of sleep deprivation and recovery sleep to better understand the molecular processes influenced by sleep and lack of sleep. This study highlights redox metabolism, chromatin regulation, and DNA…
View article: 0061 Transcriptional Dynamics of Sleep Deprivation and Subsequent Recovery Sleep in the Male Mouse Cortex
0061 Transcriptional Dynamics of Sleep Deprivation and Subsequent Recovery Sleep in the Male Mouse Cortex Open
Introduction Sleep is a critical physiological process governed by circadian and homeostatic mechanisms. The circadian clock controls sleep timing, while the sleep homeostat regulates sleep need (sleep pressure), which increases with wakef…
View article: Transcriptional dynamics of sleep deprivation and subsequent recovery sleep in the male mouse cortex
Transcriptional dynamics of sleep deprivation and subsequent recovery sleep in the male mouse cortex Open
Sleep is an essential, tightly regulated biological function. Sleep is also a homeostatic process, with the need to sleep increasing as a function of being awake. Acute sleep deprivation (SD) increases sleep need, and subsequent recovery s…
View article: Shank3 influences mammalian sleep development
Shank3 influences mammalian sleep development Open
Sleep problems are prevalent in autism spectrum disorder (ASD), can be observed before diagnosis, and are associated with increased restricted and repetitive behaviors. Therefore, sleep abnormalities may be a core feature of the disorder, …
View article: Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager Open
View article: Shank3 influences mammalian sleep development
Shank3 influences mammalian sleep development Open
Sleep problems are prevalent in Autism Spectrum Disorder (ASD), can be observed before diagnosis, and are associated with increased restricted and repetitive behaviors. Therefore, sleep abnormalities may be a core feature of the disorder, …
View article: Sleep, brain development, and autism spectrum disorders: Insights from animal models
Sleep, brain development, and autism spectrum disorders: Insights from animal models Open
Sleep is an evolutionarily conserved and powerful drive, although its complete functions are still unknown. One possible function of sleep is that it promotes brain development. The amount of sleep is greatest during ages when the brain is…
View article: Shank3 modulates sleep and expression of circadian transcription factors
Shank3 modulates sleep and expression of circadian transcription factors Open
Autism Spectrum Disorder (ASD) is the most prevalent neurodevelopmental disorder in the United States and often co-presents with sleep problems. Sleep problems in ASD predict the severity of ASD core diagnostic symptoms and have a consider…
View article: Author response: Shank3 modulates sleep and expression of circadian transcription factors
Author response: Shank3 modulates sleep and expression of circadian transcription factors Open
Article Figures and data Abstract eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Autism Spectrum Disorder (ASD…
View article: Shank3 Modulates Sleep and Expression of Circadian Transcription Factors
Shank3 Modulates Sleep and Expression of Circadian Transcription Factors Open
Autism Spectrum Disorder (ASD) is the most prevalent neurodevelopmental disorder in the United States and often co-presents with sleep problems. Sleep problems in ASD predict the severity of ASD core diagnostic symptoms and have a consider…