Trilokraj Tejasvi
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View article: Leveraging Artificial Intelligence Large Language Models for Writing Clinical Trial Proposals in Dermatology (Preprint)
Leveraging Artificial Intelligence Large Language Models for Writing Clinical Trial Proposals in Dermatology (Preprint) Open
BACKGROUND Large language models (LLMs) are becoming increasingly popular in clinical trial design but have been underutilized in research proposal development. OBJECTIVE This study compares the performance of commonly used open access …
View article: Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management
Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management Open
Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease cla…
View article: GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets Open
Psoriasis is a common, debilitating immune-mediated skin disease. Genetic studies have identified biological mechanisms of psoriasis risk, including those targeted by effective therapies. However, the genetic liability to psoriasis is not …
View article: Dermoscopy to distinguish idiopathic guttate hypomelanosis from guttate lichen sclerosus flare
Dermoscopy to distinguish idiopathic guttate hypomelanosis from guttate lichen sclerosus flare Open
Guttate lichen sclerosus (LS), a rare variant of extragenital LS, is an inflammatory disorder classically presenting with whitish patches and nodules coalescing into plaques. Idiopathic guttate hypomelanosis (IGH) is a benign, typically as…
View article: Potential Use of ChatGPT in Responding to Patient Questions and Creating Patient Resources
Potential Use of ChatGPT in Responding to Patient Questions and Creating Patient Resources Open
ChatGPT (OpenAI) is an artificial intelligence–based free natural language processing model that generates complex responses to user-generated prompts. The advent of this tool comes at a time when physician burnout is at an all-time high, …
View article: GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets Open
Psoriasis is a common, debilitating immune-mediated skin disease. Genetic studies have identified biological mechanisms of psoriasis risk, including those targeted by effective therapies. However, the genetic liability to psoriasis is not …
View article: Retrospective pharmacogenetic study of psoriasis highlights the role of <i>KLK7</i> in tumour necrosis factor signalling
Retrospective pharmacogenetic study of psoriasis highlights the role of <i>KLK7</i> in tumour necrosis factor signalling Open
Background Multiple treatment options are available for the management of psoriasis, but clinical response varies among individual patients and no biomarkers are available to facilitate treatment selection for improved patient outcomes. Ob…
View article: Purpuric Plaques on Extremities - a Unique Presentation of Mycosis Fungoides Palmaris et Plantaris
Purpuric Plaques on Extremities - a Unique Presentation of Mycosis Fungoides Palmaris et Plantaris Open
Citation: Trupiano N, Wenzel D, Hristov AC, Tejasvi T. Purpuric Plaques on Extremities - A Unique Presentation of Mycosis Fungoides Palmaris et Plantaris. Dermatol Pract Concept. 2023;13(3):e2023179. DOI: https://doi.org/10.5826/dpc.1303a1…
View article: Incidence of scabies in Michigan during the COVID‐19 pandemic
Incidence of scabies in Michigan during the COVID‐19 pandemic Open
Background By March of 2020, Coronavirus disease 2019 (COVID‐19) had spread to 72 countries and was designated as a pandemic by the World Health Organization, leading to government policies enacted to keep citizens at home to reduce the sp…
View article: <scp>CD30</scp> expression in cutaneous B‐cell lymphomas
<span>CD30</span> expression in cutaneous B‐cell lymphomas Open
Introduction CD30 expression has been infrequently described in cutaneous B‐cell lymphomas (CBCLs). We examined CD30 expression in reactive lymphoid hyperplasia (RLH) and CBCL and correlated expression with clinicopathologic features. Meth…
View article: Cutaneous B‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management
Cutaneous B‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management Open
Disease Overview Approximately one‐fourth of primary cutaneous lymphomas are B‐cell derived and are generally classified into three distinct subgroups: primary cutaneous follicle center lymphoma (PCFCL), primary cutaneous marginal zone lym…
View article: Potential Use of ChatGPT in Responding to Patient Questions and Creating Patient Resources (Preprint)
Potential Use of ChatGPT in Responding to Patient Questions and Creating Patient Resources (Preprint) Open
UNSTRUCTURED ChatGPT (OpenAI) is an artificial intelligence–based free natural language processing model that generates complex responses to user-generated prompts. The advent of this tool comes at a time when physician burnout is at an a…
View article: Two cases of challenging cutaneous lymphoid infiltrates presenting in the context of <scp>COVID</scp>‐19 vaccination: A reactive lymphomatoid papulosis‐like eruption and a bona fide lymphoma
Two cases of challenging cutaneous lymphoid infiltrates presenting in the context of <span>COVID</span>‐19 vaccination: A reactive lymphomatoid papulosis‐like eruption and a bona fide lymphoma Open
COVID‐19 infection and vaccination may be associated with a wide variety of cutaneous and immune manifestations. Here, we describe two patients who presented with monoclonal cutaneous T‐cell infiltrates that showed cytologic and immunophen…
View article: Predictors of large cell transformation in patients with Sezary Syndrome—A retrospective analysis
Predictors of large cell transformation in patients with Sezary Syndrome—A retrospective analysis Open
Background Large cell transformation (LCT) of Sezary Syndrome (SS) is a rare phenomenon. To date, there are no rigorous studies identifying risk factors for its development. Objectives Here, we seek to characterize the clinicopathologic ri…
View article: Cutaneous T‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management
Cutaneous T‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management Open
Disease Overview Cutaneous T‐cell lymphomas are a heterogenous group of T‐cell neoplasms involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS). Diagnosis The diagnosis of MF or SS req…
View article: Clinical outcomes in a cohort of patients with cutaneous T-cell lymphoma and COVID-19
Clinical outcomes in a cohort of patients with cutaneous T-cell lymphoma and COVID-19 Open
To the Editor: Patients with malignancies are at risk of poor outcomes from COVID-19.1Zhang H. Han H. He T. et al.Clinical characteristics and outcomes of COVID-19-infected cancer patients: a systematic review and meta-analysis.J Natl Canc…
View article: Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide
Transethnic analysis of psoriasis susceptibility in South Asians and Europeans enhances fine mapping in the MHC and genome wide Open
Because transethnic analysis may facilitate prioritization of causal genetic variants, we performed a genomewide association study (GWAS) of psoriasis in South Asians (SAS), consisting of 2,590 cases and 1,720 controls. Comparison with our…
View article: Patch/plaque mycosis‐fungoides‐like presentations of <i><scp>DUSP22</scp>‐</i>translocated T‐cell lymphomas
Patch/plaque mycosis‐fungoides‐like presentations of <i><span>DUSP22</span>‐</i>translocated T‐cell lymphomas Open
The DUSP22‐IRF4 gene rearrangement results in downregulation of DUSP22 , a presumed tumor suppressor in T‐cell lymphomagenesis. It has been described in some cases of primary cutaneous and systemic anaplastic large‐cell lymphoma, lymphomat…
View article: PEG10 amplification at 7q21.3 potentiates large-cell transformation in cutaneous T-cell lymphoma
PEG10 amplification at 7q21.3 potentiates large-cell transformation in cutaneous T-cell lymphoma Open
Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma, undergo large-cell transformation (LCT) in the late stage, manifesting aggressive behavior, resistance to treatments, and poor prognosis, but the mechanisms involve…
View article: Cutaneous T‐cell lymphomas: 2021 update on diagnosis, risk‐stratification, and management
Cutaneous T‐cell lymphomas: 2021 update on diagnosis, risk‐stratification, and management Open
Disease overview Cutaneous T‐cell lymphomas are a heterogenous group of T‐cell neoplasms involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS). Diagnosis The diagnosis of MF or SS req…
View article: International Dermoscopy Society criteria for non‐neoplastic dermatoses (general dermatology): validation for skin of color through a Delphi expert consensus
International Dermoscopy Society criteria for non‐neoplastic dermatoses (general dermatology): validation for skin of color through a Delphi expert consensus Open
Background The International Dermoscopy Society (IDS) recently released a set of five basic dermoscopic parameters (vessels, scales, follicular findings, “other structures,” and specific clues) encompassing a total of 31 subitems to standa…
View article: Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis
Dermoscopic Features of Mycosis Fungoides and Its Variants in Patients with Skin of Color: A Retrospective Analysis Open
Background: Mycosis fungoides (MF) is a cutaneous T-cell lymphoma that disproportionately affects people with skin of color and is difficult to diagnose.
Objective: This study characterized the dermoscopic features of MF and its subtypes …