Tengku Ain Kamalden
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View article: Visual impairment in any eye adversely affects quality of life: Psychometric validation of the Malay NEI VFQ-25
Visual impairment in any eye adversely affects quality of life: Psychometric validation of the Malay NEI VFQ-25 Open
Purpose To cross-culturally translate and adapt the National Eye Institute Visual Functioning Questionnaire (NEIVFQ-25) into Malay or Bahasa Malaysia, and to analyze its psychometric properties in a cohort of Malaysian patients with visual…
View article: Badminton-related eye injuries: A case series from Malaysia
Badminton-related eye injuries: A case series from Malaysia Open
View article: The association of cytokine levels and postnatal factors with retinopathy of prematurity
The association of cytokine levels and postnatal factors with retinopathy of prematurity Open
Purpose: Prematurity has been known to trigger several cellular pathways, leading to the clinical occurrence of retinopathy of prematurity (ROP). This study compared the levels of a panel of serum cytokines in premature infants with and wi…
View article: Special issue on ophthalmic trauma
Special issue on ophthalmic trauma Open
A prospective study on ophthalmic trauma at the Universiti Malaya Medical Centre in West Malaysia by Soong et al. in 2008 found work-related injuries to be a major cause of ophthalmic trauma.The majority of patients were males, typically o…
View article: Establishing a safe, medical officer-led intravitreal injection clinic: minimizing inadvertent crystalline lens injury
Establishing a safe, medical officer-led intravitreal injection clinic: minimizing inadvertent crystalline lens injury Open
Purpose: To study the incidence of iatrogenic crystalline lens injury in a medical officer-led intravitreal (IVT) injection clinic and to evaluate the effect of a structured training programme designed to teach medical officers how to safe…
View article: Bartonella Neuroretinitis Following Dog Bite: an Uncommon Case of Non- Feline Related Cat Scratch Disease and Review of Literature
Bartonella Neuroretinitis Following Dog Bite: an Uncommon Case of Non- Feline Related Cat Scratch Disease and Review of Literature Open
Background: Neuroretinitis is the most common form of ocular Cat Scratch Disease (CSD), caused by bacterium Bartonella Henselae, commonly transmitted to human via cat’s scratch or bite. We describe a case of Bartonella neuroretinitis with …
View article: An in Vivo Study of Intravitreal Ranibizumab Following Subretinal Inoculation of Rb Cells In Rabbits’ Eyes
An in Vivo Study of Intravitreal Ranibizumab Following Subretinal Inoculation of Rb Cells In Rabbits’ Eyes Open
Aim: This study aimed to determine the effects of a single intravitreal ranibizumab injection in rabbits induced with retinoblastoma (RB). Material and Methods: RB was induced in six New Zealand white rabbits by subretinal injection of a c…
View article: Thymoquinone in Ocular Neurodegeneration: Modulation of Pathological Mechanisms via Multiple Pathways
Thymoquinone in Ocular Neurodegeneration: Modulation of Pathological Mechanisms via Multiple Pathways Open
Thymoquinone is a naturally occurring compound and is the major component of Nigella sativa , also known as black seed or black cumin. For centuries thymoquinone has been used especially in the Middle East traditionally to treat wounds, as…
View article: Discovering the Potential of Natural Antioxidants in Age-Related Macular Degeneration: A Review
Discovering the Potential of Natural Antioxidants in Age-Related Macular Degeneration: A Review Open
Age-related macular degeneration (AMD) is a multifactorial disease associated with anatomical changes in the inner retina. Despite tremendous advances in clinical care, there is currently no cure for AMD. This review aims to evaluate the p…
View article: Association of glycemic control with progression of diabetic retinopathy in type 2 diabetes mellitus patients in Malaysia
Association of glycemic control with progression of diabetic retinopathy in type 2 diabetes mellitus patients in Malaysia Open
The risk of having microvascular complication is high among Type 2 Diabetes Mellitus (T2DM) patients. However, factors associated with the glycemic control and progression of diabetic retinopathy (DR) in T2DM patients is limited. This stud…
View article: Correction to: Epidemiology and outcomes of open globe injuries: the international globe and adnexal trauma epidemiology study (IGATES)
Correction to: Epidemiology and outcomes of open globe injuries: the international globe and adnexal trauma epidemiology study (IGATES) Open
View article: Comparative cohorts of retinopathy of prematurity outcomes of differing oxygen saturation: real-world outcomes
Comparative cohorts of retinopathy of prematurity outcomes of differing oxygen saturation: real-world outcomes Open
Objective An ongoing third epidemic of retinopathy of prematurity (ROP) is contributed largely by developing nations. We describe a cohort of infants in a single neonatal unit where two limits of oxygen saturation were administered, to sho…
View article: Changes of miRNA-15a expression in extracellular vesicles in diabetic retinopathy
Changes of miRNA-15a expression in extracellular vesicles in diabetic retinopathy Open
View article: Cases of cytomegalovirus retinitis in patients treated for cancer
Cases of cytomegalovirus retinitis in patients treated for cancer Open
Cytomegalovirus (CMV) retinitis is an opportunistic infection affecting immunocompromised patients. This case series describes 2 patients aged 19 and 10 years who were undergoing cancer treatment and were referred for complaints of worseni…
View article: Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration
Secretory proteostasis of the retinal pigmented epithelium: Impairment links to age-related macular degeneration Open
View article: Central corneal thickness changes and horizontal corneal diameter in premature infants
Central corneal thickness changes and horizontal corneal diameter in premature infants Open
To report observations of horizontal corneal diameter (HCD) and central corneal thickness (CCT) changes in premature infants with stable optic disc cupping and intraocular pressures (IOPs). The HCD and CCT at term serve as a baseline for p…
View article: Advanced glycation end products‐related modulation of cathepsin L and NF‐κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα
Advanced glycation end products‐related modulation of cathepsin L and NF‐κB signalling effectors in retinal pigment epithelium lead to augmented response to TNFα Open
The retinal pigment epithelium ( RPE ) plays a central role in neuroretinal homoeostasis throughout life. Altered proteolysis and inflammatory processes involving RPE contribute to the pathophysiology of age‐related macular degeneration ( …
View article: Association of glycemic control with progression of diabetic retinopathy in type 2 diabetes mellitus patients in Malaysia
Association of glycemic control with progression of diabetic retinopathy in type 2 diabetes mellitus patients in Malaysia Open
The risk of having microvascular complication is high among Type 2 Diabetes Mellitus (T2DM) patients. However, factors associated with the glycemic control and progression of diabetic retinopathy (DR) in T2DM patients is limited. This stud…
View article: A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma
A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma Open
Langerhans cell histiocytosis (LCH) is rarely encountered in ophthalmology practice. It is a spectrum of disorder characterized by accumulation of histiocytes in various tissues. Diagnosis is challenging as it may simulate periorbital hema…
View article: Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress
Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress Open
Our findings suggest that circulating miR-15a contributes to the pathogenesis of diabetes and supports the concept that miRNAs released by one cell type can travel through the circulation and play a role in disease progression via their tr…
View article: Modulation of cathepsin L expression and NF-kB signalling pathway effectors by advanced glycation end-products in retinal pigment epithelial cells
Modulation of cathepsin L expression and NF-kB signalling pathway effectors by advanced glycation end-products in retinal pigment epithelial cells Open
View article: Endoscopic transnasal removal of an intraconal foreign body using an image-guided surgical system
Endoscopic transnasal removal of an intraconal foreign body using an image-guided surgical system Open
Foreign bodies lodged in the intraconal space of the orbit pose a surgical challenge due to its deep location behind the globe. Image-guided endoscopic transnasal surgery facilitates the localization of the metallic foreign bodies and enab…
View article: A rare case of Arthrographis kalrae keratomycosis in a non-contact lens wearer
A rare case of Arthrographis kalrae keratomycosis in a non-contact lens wearer Open
Purpose: Keratomycoses secondary to Arthrographis kalrae are rarely reported. Previous cases involved patients with contact lens wear. Herein we report a rare case of severe fungal keratitis due to Arthrographis kalrae in a non-contact l…
View article: Bilateral Endogenous Endophthalmitis as an Initial Presentation of Klebsiella pneumoniae Bacteremia in Advanced Hepatocellular Carcinoma
Bilateral Endogenous Endophthalmitis as an Initial Presentation of Klebsiella pneumoniae Bacteremia in Advanced Hepatocellular Carcinoma Open