Tereza Duranova
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View article: Maternal and neonatal IgG against Klebsiella pneumoniae are associated with lower risk of neonatal sepsis: A case-control study of hospitalized neonates in Botswana
Maternal and neonatal IgG against Klebsiella pneumoniae are associated with lower risk of neonatal sepsis: A case-control study of hospitalized neonates in Botswana Open
Sepsis is the leading postnatal cause of neonatal mortality worldwide. Globally Klebsiella pneumoniae is the leading cause of sepsis in hospitalized neonates. This study reports the development and evaluation of an ELISA for anti- Klebsiel…
View article: Maternal and neonatal IgG against<i>Klebsiella pneumoniae</i>are associated with broad protection from neonatal sepsis: a case-control study of hospitalized neonates in Botswana
Maternal and neonatal IgG against<i>Klebsiella pneumoniae</i>are associated with broad protection from neonatal sepsis: a case-control study of hospitalized neonates in Botswana Open
Sepsis is the leading postnatal cause of neonatal mortality worldwide. Globally Klebsiella pneumoniae is the leading cause of sepsis in hospitalized neonates. This study reports development and evaluation of ELISA for anti- Klebsiella IgG …
View article: Early-life exposures to specific commensal microbes prevent type 1 diabetes
Early-life exposures to specific commensal microbes prevent type 1 diabetes Open
Early-life disruptions of the gut microbiome have long-lasting impacts on the risk of developing autoimmune diseases. How the composition of the early-life microbiota contributes to autoimmunity and whether manipulating it can prove therap…
View article: IgA deficiency destabilizes homeostasis toward intestinal microbes and increases systemic immune dysregulation
IgA deficiency destabilizes homeostasis toward intestinal microbes and increases systemic immune dysregulation Open
The ability of most patients with selective immunoglobulin A (IgA) deficiency (SIgAD) to remain apparently healthy has been a persistent clinical conundrum. Compensatory mechanisms, including IgM, have been proposed, yet it remains unclear…
View article: Arresting microbiome development limits immune system maturation and resistance to infection in mice
Arresting microbiome development limits immune system maturation and resistance to infection in mice Open
View article: Modulation of adaptive immune responses by <i>Akkermansia muciniphila</i> is restricted to an early life window in NOD mice
Modulation of adaptive immune responses by <i>Akkermansia muciniphila</i> is restricted to an early life window in NOD mice Open
Early life microbiota drive immune system development and influence risk for immune dysfunction later in life, including the development of type 1 diabetes (T1D). Which specific early-life microbes modulate diabetes risk and the timing of …
View article: Arresting microbiome development limits immune system maturation and resistance to infection
Arresting microbiome development limits immune system maturation and resistance to infection Open
Disruptions to the intestinal microbiome during weaning lead to long-term negative effects on host immune function. However, the critical host-microbe interactions occurring during weaning required for healthy immune system development rem…
View article: IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation
IgA deficiency destabilizes immunological homeostasis towards intestinal microbiota and increases the risk of systemic immune dysregulation Open
Summary Mammals produce large quantities of mucosal and systemic antibodies that maintain the intestinal barrier, shape the intestinal microbiome and promote lifelong mutualism with commensal microbes. Here, we developed an integrated host…
View article: IgA deficiency Alters Systemic Immune Response to Commensal Gut Microbes
IgA deficiency Alters Systemic Immune Response to Commensal Gut Microbes Open