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View article: Fostering medication review competence of pharmacy students: An assessment by students and their preceptors after advanced‐level practical internship
Fostering medication review competence of pharmacy students: An assessment by students and their preceptors after advanced‐level practical internship Open
Aims The aim of this study was to introduce a new assessment method for pharmacy students' real‐life competence in reviewing medications after obligatory advanced‐level practical internship in Finland. Methods The new medication review (MR…
View article: The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity
The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity Open
Gut microbiota is linked with health, including obesity, in the general population. It is unknown whether adiposity at postpartum is influenced by gut microbiota already during pregnancy. We investigated the association between the gut mic…
View article: Postpartum Body Composition in Women With Overweight: Associations With Diet During Pregnancy
Postpartum Body Composition in Women With Overweight: Associations With Diet During Pregnancy Open
Objective Weight management during the first few years postpartum is considered important for the prevention of future metabolic disturbances. Body fat percentage measured using air displacement plethysmography is an accurate marker of bod…
View article: The Impact of Maternal Supplementation of Fish Oil and/or Probiotics During Pregnancy on the Serum Metabolomic Profile From Infancy to Childhood: Secondary Analysis of a Randomized Placebo-Controlled Trial
The Impact of Maternal Supplementation of Fish Oil and/or Probiotics During Pregnancy on the Serum Metabolomic Profile From Infancy to Childhood: Secondary Analysis of a Randomized Placebo-Controlled Trial Open
NCT01922791 (https://clinicaltrials.gov/ct2/show/NCT01922791.
View article: Hand muscle strength in Parkinson's disease: A Sarcopenic epiphenomenon or a meaningful biomarker?
Hand muscle strength in Parkinson's disease: A Sarcopenic epiphenomenon or a meaningful biomarker? Open
Upper limb muscle strength remains largely preserved in mild to moderate PD and does not reliably reflect dopaminergic function or disease progression. Although sarcopenia has been reported in PD, grip strength declines in parallel with mo…
View article: Increased frontal [123I]FP-CIT binding in Parkinson’s disease patients with self-reported REM sleep behavior disorder
Increased frontal [123I]FP-CIT binding in Parkinson’s disease patients with self-reported REM sleep behavior disorder Open
Rapid eye movement (REM) sleep behavior disorder (RBD) is a frequent non-motor symptom of Parkinson's disease (PD) and a potential early marker of synucleinopathy-related neurodegeneration. While striatal dopaminergic dysfunction in PD-RBD…
View article: Addressing sexual problems: General practitioners' practice patterns
Addressing sexual problems: General practitioners' practice patterns Open
Increasing GP education in sexual medicine is essential to enhance their knowledge of sexual health and improve their recognition of sexual health problems during patient consultations. Clinical practice guidelines regarding the treatment …
View article: Maternal diet and gestational diabetes mellitus modestly influence children's growth during their first 24 months
Maternal diet and gestational diabetes mellitus modestly influence children's growth during their first 24 months Open
Objective To evaluate whether diet and gestational diabetes mellitus (GDM) during pregnancy influence children's growth during their first 24 months. Methods Growth data of children ( n = 378) of women with overweight/obesity were obtained…
View article: Engagement with patients’ sexual problems: a comparative study among general practitioners and obstetrician-gynecologists
Engagement with patients’ sexual problems: a comparative study among general practitioners and obstetrician-gynecologists Open
Objectives: Even though good sexual health is an important part of well-being, the evaluation of patients’ sexual problems is not necessarily routine for physicians. We compared engagement (attitudes, barriers to bringing up, and practice …
View article: GENERAL PRACTITIONERS’ PRACTICE PATTERNS: DIAGNOSING AND TREATING SEXUAL PROBLEMS
GENERAL PRACTITIONERS’ PRACTICE PATTERNS: DIAGNOSING AND TREATING SEXUAL PROBLEMS Open
Objectives To achieve good general health, the status of good sexual health is needed. Nonetheless, sexual problems are common and concern all people regardless of race, gender, or sexual orientation. Often a general practitioner (GP) is t…
View article: Rib-sparing scalenotomy in thoracic outlet syndrome treatment: A systematic review and meta-analysis
Rib-sparing scalenotomy in thoracic outlet syndrome treatment: A systematic review and meta-analysis Open
Background and Aims: The majority of neurogenic thoracic outlet syndrome (NTOS) surgery still involves removal of the first rib. A rib-sparing procedure has also been found to give a good result, but no meta-analysis has been published abo…
View article: State anxiety is associated with hormonal, cardiovascular, and sleep parameters in Finnish postmenopausal women
State anxiety is associated with hormonal, cardiovascular, and sleep parameters in Finnish postmenopausal women Open
The change in psychological symptoms during the follow-up was modest. At postmenopause, distress and depressive symptoms were associated with a range of physiological and non-physiological parameters, but state anxiety only with physiologi…
View article: Stability and Accuracy of a Diagnosis of Parkinson Disease Over 10 Years
Stability and Accuracy of a Diagnosis of Parkinson Disease Over 10 Years Open
This study demonstrates significant diagnostic instability in PD, with 13.3% of diagnoses revised, primarily within 2 years. When DLB is considered separately, the revision rate increases to 17.7%. Despite frequent DAT imaging and limited …
View article: Small dense low-density lipoprotein as biomarker in the elderly
Small dense low-density lipoprotein as biomarker in the elderly Open
Lipid and apolipoprotein concentrations of the elderly were high compared to the recommended target values. In addition, lipid and apolipoprotein baseline concentrations were not higher in the ASCVD group than in the control group. Our res…
View article: Factors contributing to self-rated health in community-dwelling independent 75-year-old Finns: a population-based cross-sectional cohort study
Factors contributing to self-rated health in community-dwelling independent 75-year-old Finns: a population-based cross-sectional cohort study Open
The study is registered in ClinicalTrials.gov (Identifier: NCT05634239). Retrospectively registered.
View article: Correction to: Sleep apnea prevalence and severity after coronary revascularization versus no intervention: a systematic review & meta-analysis
Correction to: Sleep apnea prevalence and severity after coronary revascularization versus no intervention: a systematic review & meta-analysis Open
View article: The effect of maternal risk factors during pregnancy on children's motor development at 5–6 years
The effect of maternal risk factors during pregnancy on children's motor development at 5–6 years Open
NCT01922791.
View article: Decolonization of methicillin-resistant <i>Staphylococcus aureus</i> – effectiveness of decolonization treatment
Decolonization of methicillin-resistant <i>Staphylococcus aureus</i> – effectiveness of decolonization treatment Open
Objectives: The aim of this study was to describe the efficacy of decolonization treatments given in Hospital District of Southwest Finland (HDSWF) in 2007–2016 and to analyze the key elements for successful decolonization treatment. Durat…
View article: High-sensitivity cardiac troponin T and N-terminal b-type natriuretic propeptide are associated with cardiac and all-cause mortality in older adults – A population-based ten-year follow-up study
High-sensitivity cardiac troponin T and N-terminal b-type natriuretic propeptide are associated with cardiac and all-cause mortality in older adults – A population-based ten-year follow-up study Open
Our study shows that older population with higher cTnT and proBNP concentrations have an increased risk of cardiovascular and all-cause mortality. Acknowledging the elevated risk may aid in targeting follow-up, prevention, and treatment ad…
View article: Striatal Dopaminergic Function and Motor Slowing in Essential Tremor Plus
Striatal Dopaminergic Function and Motor Slowing in Essential Tremor Plus Open
Background While previous imaging studies have generally shown normal striatal dopamine transporter (DAT) binding in essential tremor (ET), emerging evidence suggests a partial dopaminergic mechanism in this condition and an epidemiologica…
View article: Can a Universal Mindfulness Intervention in Schools Reduce <scp>ADHD</scp> Symptoms among Adolescents? A Cluster Randomized Controlled Trial
Can a Universal Mindfulness Intervention in Schools Reduce <span>ADHD</span> Symptoms among Adolescents? A Cluster Randomized Controlled Trial Open
Existing studies suggest that mindfulness‐based interventions (MBIs) can reduce ADHD symptoms when delivered as targeted clinical programs to young people diagnosed with ADHD. However, there is currently a lack of research on whether MBIs …
View article: Clinical Risk Factors for Cutaneous Squamous Cell Carcinoma in Patients with Actinic Keratosis or Cutaneous Squamous Cell Carcinoma in Situ: A Retrospective Double-cohort Study
Clinical Risk Factors for Cutaneous Squamous Cell Carcinoma in Patients with Actinic Keratosis or Cutaneous Squamous Cell Carcinoma in Situ: A Retrospective Double-cohort Study Open
Actinic keratosis and cutaneous squamous cell carcinoma in situ are precancerous forms of cutaneous squamous cell carcinoma. In this single-centre retrospective study, patients with histopathologically confirmed actinic keratosis (n = 121)…
View article: Infective endocarditis in a Finnish tertiary care hospital: from etiology to embolic events
Infective endocarditis in a Finnish tertiary care hospital: from etiology to embolic events Open
Our study suggests that enterococcal IE is often associated with a previous healthcare procedure or hospital admission and heart failure. Staphylococcus aureus etiology and IE of the multiple valves are associated with a higher rate…
View article: Can a Universal Mindfulness Programme Improve Well-Being in Adolescents?
Can a Universal Mindfulness Programme Improve Well-Being in Adolescents? Open
Background Approx. 14% of adolescents experience mental health disorders. Mindfulness-based interventions (MBIs) could be one way to support adolescents’ well-being. We investigated the effectiveness of a 9-week school-based mindfulness in…
View article: Can a mindfulness programme in schools for students with ADHD symptoms improve emotional well-being?
Can a mindfulness programme in schools for students with ADHD symptoms improve emotional well-being? Open
Background This study employs a cluster randomized controlled trial to investigate the effectiveness of a universal mindfulness-based intervention (MBI) in classrooms in improving emotional well-being and emotion regulation among adolescen…
View article: Does mindfulness program reduce stress and enhance self-kindness in schools? Healthy Learning Mind
Does mindfulness program reduce stress and enhance self-kindness in schools? Healthy Learning Mind Open
Introduction There is a scarcity of research with high quality methods on the effectiveness of mindfulness-based interventions (MBIs) on adolescents’ mental well-being. This study investigates the MBI effects on adolescents’ stress and sel…
View article: Neuroinflammation in Parkinson’s disease: A study with [11C]PBR28 PET and cerebrospinal fluid markers
Neuroinflammation in Parkinson’s disease: A study with [11C]PBR28 PET and cerebrospinal fluid markers Open
Associations between CSF biomarkers, motor disability and [11C]PBR28 VT in the striatum and SN may support a role for neuroinflammation in PD.
View article: Morning tiredness and insomnia symptoms are associated with increased blood pressure in midlife women
Morning tiredness and insomnia symptoms are associated with increased blood pressure in midlife women Open
In healthy midlife women, a change blood pressure is related to the development of insomnia symptoms during menopausal transition. In postmenopausal women, a high evening blood pressure may be associated with morning tiredness and a reduce…
View article: Adherence to diet recommendations in women with gestational diabetes mellitus
Adherence to diet recommendations in women with gestational diabetes mellitus Open
View article: Disease Severity and Cytokine Expression in the Rhinovirus-Induced First Wheezing Episode
Disease Severity and Cytokine Expression in the Rhinovirus-Induced First Wheezing Episode Open
Wheezing children infected with rhinovirus (RV) have a markedly increased risk of subsequently developing recurrencies and asthma. No previous studies have assessed the association between cytokine response and the severity of acute illnes…