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View article: Multimethod feasibility evaluation of smoking cessation intervention for patients receiving opioid agonist therapy
Multimethod feasibility evaluation of smoking cessation intervention for patients receiving opioid agonist therapy Open
Background Among patients receiving opioid agonist therapy, 85% are active tobacco smokers. Despite the significant impact of smoking-related pulmonary diseases on disability and mortality in this population, less than 10% successfully qui…
View article: Blood-based tumor mutational burden as a biomarker in unresectable non-small cell lung cancer treated with chemoradiotherapy and durvalumab
Blood-based tumor mutational burden as a biomarker in unresectable non-small cell lung cancer treated with chemoradiotherapy and durvalumab Open
Introduction Chemoradiotherapy followed by durvalumab is a potentially curative treatment for unresectable, locally advanced non-small cell lung cancer (NSCLC), but clinical outcomes remain highly variable. Identifying robust biomarkers is…
View article: The effect of fruit smoothie supplementation on psychological distress and biomarkers among people with opioid dependence receiving opioid agonist therapy: a randomized controlled trial
The effect of fruit smoothie supplementation on psychological distress and biomarkers among people with opioid dependence receiving opioid agonist therapy: a randomized controlled trial Open
Background Unhealthy diets are common among individuals with opioid dependence. While fruit- and vegetable-rich diets have shown mental health benefits, evidence is limited for those receiving opioid agonist therapy (OAT). This trial evalu…
View article: Integrating an exercise program into opioid agonist therapy: a pilot study on feasibility, fitness improvements, and participation challenges.
Integrating an exercise program into opioid agonist therapy: a pilot study on feasibility, fitness improvements, and participation challenges. Open
This pilot study suggests that integrating structured exercise into OAT can be feasible and improve aerobic fitness. However, increased psychological distress and fatigue might indicate the need for additional support. The low attendance r…
View article: To smoothie or not to smoothie? A mixed-method approach of nutrition pilot intervention among individuals in opioid agonist treatment
To smoothie or not to smoothie? A mixed-method approach of nutrition pilot intervention among individuals in opioid agonist treatment Open
Background Patients with substance dependence typically have unhealthy diets and low degree of nutritional awareness. They frequently face nutritional deficiencies in both micro- and macronutrients, which can have a significant impact on t…
View article: High-Dose Versus Standard-Dose Twice-Daily Thoracic Radiotherapy in Limited-Stage SCLC: Final Survival Data, Long-Term Toxicity, and Relapse Patterns in a Randomized, Open-Label, Phase II Trial
High-Dose Versus Standard-Dose Twice-Daily Thoracic Radiotherapy in Limited-Stage SCLC: Final Survival Data, Long-Term Toxicity, and Relapse Patterns in a Randomized, Open-Label, Phase II Trial Open
Twice-daily TRT of 60 Gy/40 fractions was well tolerated and prolonged survival compared with 45 Gy/30 fractions in patients with limited-stage SCLC. This trial is registered at ClinicalTrials.gov: NCT02041845.
View article: Integrated Nicotine Replacement and Behavioral Support to Reduce Smoking in Opioid Agonist Therapy
Integrated Nicotine Replacement and Behavioral Support to Reduce Smoking in Opioid Agonist Therapy Open
Importance Approximately 85% of individuals receiving opioid agonist therapy for opioid dependence smoke tobacco. Despite the significant health risks associated with smoking-related diseases, there has been limited evaluation of smoking i…
View article: Update of statistical analysis plan for: Effect of fruit smoothie supplementation on psychological distress among people with substance use disorders receiving opioid agonist therapy: protocol for a randomised controlled trial (FruktBAR)
Update of statistical analysis plan for: Effect of fruit smoothie supplementation on psychological distress among people with substance use disorders receiving opioid agonist therapy: protocol for a randomised controlled trial (FruktBAR) Open
This update provides a statistical analysis plan for an earlier protocol version for the randomized controlled trial, FruktBAR. This randomized control trial will evaluate the impact of daily fruit smoothie supplementation on psychological…
View article: A qualitative study of experiences with physical activity among people receiving opioid agonist therapy
A qualitative study of experiences with physical activity among people receiving opioid agonist therapy Open
View article: Healthy eating among people on opioid agonist therapy: a qualitative study of patients’ experiences and perspectives
Healthy eating among people on opioid agonist therapy: a qualitative study of patients’ experiences and perspectives Open
People with substance use disorders often have unhealthy diets, high in sweets and processed foods but low in nutritious items like fruits and vegetables, increasing noncommunicable disease risks. This study investigates healthy eating per…
View article: Liver stiffness and associated risk factors among people with a history of injecting drugs: a prospective cohort study
Liver stiffness and associated risk factors among people with a history of injecting drugs: a prospective cohort study Open
View article: Integrated exercise program in opioid agonist therapy clinics and effect on psychological distress: study protocol for a randomized controlled trial (BAReAktiv)
Integrated exercise program in opioid agonist therapy clinics and effect on psychological distress: study protocol for a randomized controlled trial (BAReAktiv) Open
Background Substance use disorder is associated with unhealthy lifestyle choices, resulting in adverse social and health consequences. People with opioid use disorder receiving opioid agonist therapy, in particular, have high morbidity and…
View article: The association of psychological distress and economic and health worries with tobacco smoking behavior during the COVID-19 pandemic: a two-year longitudinal cohort study
The association of psychological distress and economic and health worries with tobacco smoking behavior during the COVID-19 pandemic: a two-year longitudinal cohort study Open
Background The COVID-19 pandemic and other life events may trigger worries and psychological distress. These impacts may lead to unhealthy behaviors, such as tobacco smoking, but the degree of such associations is unclear. The current thre…
View article: Update of statistical analysis plan for: Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR)
Update of statistical analysis plan for: Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR) Open
This protocol paper presents an updated statistical analysis plan of the protocol of a randomised controlled trial. The randomised controlled trial investigates the effect of integrating smoking cessation interventions at outpatient opioid…
View article: High-Dose Versus Standard Dose Twice-Daily Thoracic Radiotherapy in Limited Stage Small-Cell Lung Cancer: Final Survival Data, Long Term Toxicity and Relapse Patterns in a Randomised, Open-Label, Phase 2 Trial
High-Dose Versus Standard Dose Twice-Daily Thoracic Radiotherapy in Limited Stage Small-Cell Lung Cancer: Final Survival Data, Long Term Toxicity and Relapse Patterns in a Randomised, Open-Label, Phase 2 Trial Open
View article: A qualitative study on people with opioid use disorders’ perspectives on smoking and smoking cessation interventions
A qualitative study on people with opioid use disorders’ perspectives on smoking and smoking cessation interventions Open
Introduction Smoking-related diseases are major contributors to disability and shorter life expectancy among opioid-dependent patients. Smoking prevalence is considerably higher for opioid-dependent persons than among the general populatio…
View article: “The challenge is the complexity” – A qualitative study about decision-making in advanced lung cancer treatment
“The challenge is the complexity” – A qualitative study about decision-making in advanced lung cancer treatment Open
Our study suggests it is difficult to develop an applicable DA for advanced lung cancer after first-line therapy that meets the composite requirements of stakeholders. Comprehensive decision support interventions are needed to address orga…
View article: 'The Challenge is the Complexity' – A Qualitative Study About Decision-Making in Advanced Lung Cancer Treatment
'The Challenge is the Complexity' – A Qualitative Study About Decision-Making in Advanced Lung Cancer Treatment Open
View article: Effect of fruit smoothie supplementation on psychological distress among people with substance use disorders receiving opioid agonist therapy: protocol for a randomised controlled trial (FruktBAR)
Effect of fruit smoothie supplementation on psychological distress among people with substance use disorders receiving opioid agonist therapy: protocol for a randomised controlled trial (FruktBAR) Open
View article: Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR)
Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR) Open
Background About 85% of patients receiving opioid agonist therapy (OAT) for opioid dependence are smoking tobacco. Although smoke-related pulmonary diseases are significant contributors to morbidity and mortality, few smoking cessation int…
View article: Integrated exercise program in opioid agonist therapy clinics and effect on psychological distress: Study protocol for a randomised controlled trial (BAReAktiv)
Integrated exercise program in opioid agonist therapy clinics and effect on psychological distress: Study protocol for a randomised controlled trial (BAReAktiv) Open
Background Substance use disorder is associated with unhealthy lifestyle choices, resulting in adverse social and health consequences. People with opioid use disorder receiving opioid agonist therapy, in particular, have high morbidity and…
View article: Integration of Smoking Cessation Into Standard Treatment for Patients Receiving Opioid Agonist Therapy Who Are Smoking Tobacco: Protocol for a Randomised Controlled Trial (ATLAS4LAR)
Integration of Smoking Cessation Into Standard Treatment for Patients Receiving Opioid Agonist Therapy Who Are Smoking Tobacco: Protocol for a Randomised Controlled Trial (ATLAS4LAR) Open
Background: About 85% of patients receiving opioid agonist therapy (OAT) for opioid dependence are smoking tobacco. Although smoke-related pulmonary diseases are significant contributors to morbidity and mortality, few smoking cessation in…
View article: Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics among People with Severe Substance Use Disorders: A Cohort Study from Western Norway
Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics among People with Severe Substance Use Disorders: A Cohort Study from Western Norway Open
People with severe substance use disorder (SUD) have a higher burden of micronutrient deficiency compared with the general population. The aim of this study was to investigate vitamin B12 status and risk factors of deficiency related to su…
View article: Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics Among People with Severe Substance Use Disorders: A Cohort Study from Western Norway
Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics Among People with Severe Substance Use Disorders: A Cohort Study from Western Norway Open
Background: People with severe substance use disorder (SUD) have a markedly higher burden of micronutrient deficiency compared to the general population. There is limited data available about vitamin B12 status among people with severe SUD…
View article: Patient-reported health-related quality of life from a randomized phase II trial comparing standard-dose with high-dose twice daily thoracic radiotherapy in limited stage small-cell lung cancer
Patient-reported health-related quality of life from a randomized phase II trial comparing standard-dose with high-dose twice daily thoracic radiotherapy in limited stage small-cell lung cancer Open
View article: P17.02 Durvalumab After chemoRadioTherapy (DART) for NSCLC Patients – a Phase II Translational and Biomarker Study
P17.02 Durvalumab After chemoRadioTherapy (DART) for NSCLC Patients – a Phase II Translational and Biomarker Study Open
View article: Randomized phase III trial comparing switch-maintenance pemetrexed with observation followed by pemetrexed at progression in advanced NSCLC
Randomized phase III trial comparing switch-maintenance pemetrexed with observation followed by pemetrexed at progression in advanced NSCLC Open
Objectives: Two phase III trials show that maintenance pemetrexed therapy after platinum-doublet chemotherapy prolongs overall survival (OS) and progression free survival (PFS) in advanced non-squamous non-small-cell lung cancer (NSCLC). H…
View article: P1.01-09 Randomized Trial Comparing Maintenance Pemetrexed with Observation Followed by Pemetrexed at Progression in Advanced NSCLC
P1.01-09 Randomized Trial Comparing Maintenance Pemetrexed with Observation Followed by Pemetrexed at Progression in Advanced NSCLC Open
View article: Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study
Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study Open
View article: Additional file 2: of Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study
Additional file 2: of Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study Open
a, form sent to clinicians for information about treatment completion. b, translation of form sent to clinicians for information about treatment completion. (ZIP 680 kb)