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View article: Frailty and transitions across cardiometabolic disease states: evidence from multistate models in a 16-year Chinese cohort
Frailty and transitions across cardiometabolic disease states: evidence from multistate models in a 16-year Chinese cohort Open
Frailty is a prevalent geriatric syndrome, but its role in cardiometabolic disease (CMD) progression remains unclear. We examined whether frailty predicted CMD transitions. We included 22,754 participants aged 50+ from the Guangzhou Bioban…
View article: Development and multicenter validation of a novel model for selective screening of gestational diabetes mellitus: the Vietnam gestational diabetes mellitus study
Development and multicenter validation of a novel model for selective screening of gestational diabetes mellitus: the Vietnam gestational diabetes mellitus study Open
A nomogram incorporating four routinely assessed clinical parameters offers good predictive accuracy for gestational diabetes mellitus. This model may facilitate early identification and targeted intervention for high-risk pregnant women i…
View article: Electrocardiogram abnormalities and cardiovascular risk prediction in older Chinese: the Guangzhou Biobank Cohort Study
Electrocardiogram abnormalities and cardiovascular risk prediction in older Chinese: the Guangzhou Biobank Cohort Study Open
Background Evidence on the associations of multiple minor ECG abnormalities (EA) with cardiovascular disease (CVD) and mortality in older populations is limited, particularly whether a weighted EA score better predicts CVD risk than a sing…
View article: External Validation of Lung Cancer Prediction Models Combining Epidemiological Predictors in Chinese Ever and Never Smokers: Guangzhou Biobank Cohort Study
External Validation of Lung Cancer Prediction Models Combining Epidemiological Predictors in Chinese Ever and Never Smokers: Guangzhou Biobank Cohort Study Open
Objective This study aimed to externally validate existing lung cancer models using data from the Guangzhou Biobank Cohort Study (GBCS) and compare their predictive performance for Chinese ever and never smokers. Methods We evaluated the d…
View article: Development and Multicenter Validation of a Novel Model for Selective Screening of Gestational Diabetes Mellitus: TheVietnam Gestational Diabetes Mellitus Study
Development and Multicenter Validation of a Novel Model for Selective Screening of Gestational Diabetes Mellitus: TheVietnam Gestational Diabetes Mellitus Study Open
Aims Gestational diabetes mellitus is commonly observed in pregnant women and is associated with an increased risk of adverse outcomes for both mother and child, not only during pregnancy but also in the long term thereafter. The present s…
View article: Association of Perceived Xingfu With Health-Related and Socioeconomic Factors Among Hong Kong Chinese Adults: Cross-Sectional Study Using a Novel Single-Item Tool
Association of Perceived Xingfu With Health-Related and Socioeconomic Factors Among Hong Kong Chinese Adults: Cross-Sectional Study Using a Novel Single-Item Tool Open
Background Xingfu (幸福), a Chinese term, holds meanings that transcend Western concepts of happiness; it is modern and highly valued in China. Despite its centrality to China’s national discourse on xingfu, there are no validated tools for …
View article: Workplace second-hand smoke exposure and its association with respiratory symptoms: Findings from cross-sectional surveys 2015–2020
Workplace second-hand smoke exposure and its association with respiratory symptoms: Findings from cross-sectional surveys 2015–2020 Open
Eight to thirteen years after banning smoking at all indoor workplaces, SHS exposure at workplaces was prevalent in outdoor occupations. Exposure to SHS at workplaces was associated with self-reported respiratory symptoms in never and ex-s…
View article: Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice
Impact of short-term housing temperature alteration on metabolic parameters and adipose tissue in female mice Open
Introduction Ambient temperature significantly influences physiological and metabolic processes in rodents, affecting obesity and related disorders. Mice housed below thermoneutral temperatures exhibit increased energy expenditure and symp…
View article: Systematic analysis of associations between obesity and memory decline
Systematic analysis of associations between obesity and memory decline Open
Despite the development of numerous obesity indicators, the optimal measure associated with memory remains to be elucidated. We examined and compared these associations whilst also exploring potential interactions with education. We analys…
View article: High-touch surfaces with moderate contamination levels as key nodes in microbial dissemination
High-touch surfaces with moderate contamination levels as key nodes in microbial dissemination Open
Hand-touching of contaminated surfaces is an established mode of infection transmission. However, the role of touch-mediated pathogen spread remains debatable, as frequently touched surfaces may exhibit low pathogen loads. To inform diseas…
View article: Prognostic models for lung cancer in smokers and nonsmokers: an updated systematic review and meta-analysis
Prognostic models for lung cancer in smokers and nonsmokers: an updated systematic review and meta-analysis Open
Background Lung cancer is the leading cause of cancer-related mortality, and while low-dose computed tomography screening may reduce mortality, emerging prognostic models show superior discriminative efficacy compared to age- and smoking h…
View article: Chest x‐ray aortic size and risk of death and cardiovascular disease in older Chinese: Guangzhou biobank cohort study
Chest x‐ray aortic size and risk of death and cardiovascular disease in older Chinese: Guangzhou biobank cohort study Open
Background Chest radiograph can independently predict adverse outcomes in outpatients. We examined the associations of aortic knob width (AKW), ascending aortic length (AAL), and ascending aortic width (AAW) from chest x‐ray with death and…
View article: Associations of Home-Based Individual and Family Exercise with Personal and Family Well-Being Amid the COVID-19 Pandemic: A Population-Based Survey in Hong Kong
Associations of Home-Based Individual and Family Exercise with Personal and Family Well-Being Amid the COVID-19 Pandemic: A Population-Based Survey in Hong Kong Open
Exercise benefits individuals, but research about exercising with family members (EFM) and personal and family well-being is scarce. We investigated the associations of home-based individual exercise (IE) and EFM with personal and family w…
View article: Prevalence and Risk Factors of Anemia, Iron Deficiency in Pregnant Women Seeking Care at The Center for Disease Control in Dong Nai Province, Vietnam
Prevalence and Risk Factors of Anemia, Iron Deficiency in Pregnant Women Seeking Care at The Center for Disease Control in Dong Nai Province, Vietnam Open
Background: Iron-deficiency anemia (IDA) remains a significant public health issue among pregnant women, contributing to adverse maternal and neonatal outcomes. Despite national iron supplementation programs, anemia persists as a prevalent…
View article: Telephone Counseling and Messaging Guided by Mobile Profiling of Tobacco Users for Smoking Cessation
Telephone Counseling and Messaging Guided by Mobile Profiling of Tobacco Users for Smoking Cessation Open
Importance Evidence-based pharmacotherapy and behavioral therapy could increase tobacco abstinence but are underused and require further investigation. Objective To evaluate the effectiveness of a novel mobile health (mHealth) profiling vi…
View article: Trajectories of lipid profile with cognitive function: 12-year follow-up of Guangzhou Biobank cohort study
Trajectories of lipid profile with cognitive function: 12-year follow-up of Guangzhou Biobank cohort study Open
Studies on the trajectories of lipid profile with cognitive decline are scarce and inconsistent. We examined this association and explored potential effect modification. Lipid profiles including high-density lipoprotein cholesterol (HDL-C)…
View article: Real-World Effectiveness of Nicotine Replacement Therapy Sampling in Chinese Women of a Sex-Specific Smoking Cessation Program in Hong Kong, China
Real-World Effectiveness of Nicotine Replacement Therapy Sampling in Chinese Women of a Sex-Specific Smoking Cessation Program in Hong Kong, China Open
Introduction Nicotine replacement therapy (NRT) sampling has been shown effective in increasing smoking abstinence by trials, but the real-world effectiveness in women is unknown. We examined the effectiveness of 1-week NRT sampling combin…
View article: Prevalence, risk factors, and outcomes of systemic sclerosis–associated interstitial lung disease in a Chinese population
Prevalence, risk factors, and outcomes of systemic sclerosis–associated interstitial lung disease in a Chinese population Open
Interstitial lung disease was prevalent among SSc patients in this cohort and the majority exhibited disease progression. Comprehensive clinical assessment, supported by investigations such as CRP level measurement, is essential to identif…
View article: Prevalence and Predictors of Suspected Metabolic Dysfunction‐Associated Steatotic Liver Disease in Adolescents in the United States
Prevalence and Predictors of Suspected Metabolic Dysfunction‐Associated Steatotic Liver Disease in Adolescents in the United States Open
Background Nomenclature for steatotic liver disease has been updated to include metabolic dysfunction‐associated steatotic liver disease (MASLD), which requires the presence of hepatic steatosis and at least one cardiometabolic risk factor…