Thamir Hamoh
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View article: Diamond Surfaces with Lateral Gradients for Systematic Optimization of Surface Chemistry for Relaxometry – a Low-Pressure Plasma-Based Approach
Diamond Surfaces with Lateral Gradients for Systematic Optimization of Surface Chemistry for Relaxometry – a Low-Pressure Plasma-Based Approach Open
Diamond is increasingly popular because of its unique material properties. Diamond defects called nitrogen vacancy (NV) centers allow for measurements with unprecedented sensitivity. However, to achieve ideal sensing performance, NV center…
View article: Diamond surfaces with lateral gradients for systematic optimization of surface chemistry for relaxometry -- A low pressure plasma-based approach
Diamond surfaces with lateral gradients for systematic optimization of surface chemistry for relaxometry -- A low pressure plasma-based approach Open
Diamond is increasingly popular because of its unique material properties. Diamond defects called nitrogen vacancy (NV) centers allow measurements with unprecedented sensitivity. However, to achieve ideal sensing performance NV centers nee…
View article: Functionalized Fluorescent Nanodiamonds for Simultaneous Drug Delivery and Quantum Sensing in HeLa Cells
Functionalized Fluorescent Nanodiamonds for Simultaneous Drug Delivery and Quantum Sensing in HeLa Cells Open
Here, we present multifunctional fluorescent nanodiamonds (FNDs) for simultaneous drug delivery and free radical detection. For this purpose, we modified FNDs containing nitrogen vacancy (NV) centers with a diazoxide derivative. We found t…
View article: Relaxometry for detecting free radical generation during Bacteria's response to antibiotics
Relaxometry for detecting free radical generation during Bacteria's response to antibiotics Open
Free radical generation plays a key role in killing bacteria by antibiotics. However, radicals are short-lived and reactive, and thus difficult to detect for the state of the art. Here we use a technique which allows optical nanoscale magn…
View article: Nanoscale MRI for Selective Labeling and Localized Free Radical Measurements in the Acrosomes of Single Sperm Cells
Nanoscale MRI for Selective Labeling and Localized Free Radical Measurements in the Acrosomes of Single Sperm Cells Open
Free radicals play a major role in sperm development, including maturation and fertilization, but they are also linked to infertility. Since they are short-lived and reactive, they are challenging to detect with state of the art methodolog…
View article: Quantum Sensing of Free Radicals in Primary Human Dendritic Cells
Quantum Sensing of Free Radicals in Primary Human Dendritic Cells Open
Free radicals are crucial indicators for stress and appear in all kinds of pathogenic conditions, including cancer, cardiovascular diseases, and infection. However, they are difficult to detect due to their reactivity and low abundance. We…
View article: Fluorescent Nanodiamonds for Detecting Free-Radical Generation in Real Time during Shear Stress in Human Umbilical Vein Endothelial Cells
Fluorescent Nanodiamonds for Detecting Free-Radical Generation in Real Time during Shear Stress in Human Umbilical Vein Endothelial Cells Open
Free-radical generation is suspected to play a key role in cardiovascular diseases. Another crucial factor is shear stress. Human umbilical vein endothelial cells (HUVECS), which form the lining of blood vessels, require a physiological sh…
View article: Free radical detection in living cells with relaxometry
Free radical detection in living cells with relaxometry Open
There is a growing evidence for a correlation between free radicals and the formation of diseases. Free radicals or oxidative stress are expected to be linked to various pathogenic conditions which impact cells. The oxidative stress is a r…
View article: Targeting Nanodiamonds to the Nucleus in Yeast Cells
Targeting Nanodiamonds to the Nucleus in Yeast Cells Open
Nanodiamonds are widely used for drug delivery, labelling or nanoscale sensing. For all these applications it is highly beneficial to have control over the intracellular location of the particles. For the first time, we have achieved targe…
View article: Quantum monitoring the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidant
Quantum monitoring the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidant Open
Free radicals play a key role in the ageing process. The strongly debated free radical theory of ageing even states that damage caused by free radicals is the main cause of aging on a cellular level. However, free radicals are small, react…
View article: The Fate of Lipid-Coated and Uncoated Fluorescent Nanodiamonds during Cell Division in Yeast
The Fate of Lipid-Coated and Uncoated Fluorescent Nanodiamonds during Cell Division in Yeast Open
Fluorescent nanodiamonds are frequently used as biolabels. They have also recently been established for magnetic resonance and temperature sensing at the nanoscale level. To properly use them in cell biology, we first have to understand th…
Nanodiamonds as multi-purpose labels for microscopy Open
Nanodiamonds containing fluorescent nitrogen-vacancy centers are increasingly attracting interest for use as a probe in biological microscopy. This interest stems from (i) strong resistance to photobleaching allowing prolonged fluorescence…