Thamiris Cirelli
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View article: The Impact of Type 2 Diabetes Mellitus on Non-Surgical Periodontal Treatment: A Non-Randomized Clinical Trial
The Impact of Type 2 Diabetes Mellitus on Non-Surgical Periodontal Treatment: A Non-Randomized Clinical Trial Open
Background/Objectives: Periodontitis (P), a chronic inflammatory condition that affects the supportive tissues around the teeth, is three to four times more prevalent in individuals with diabetes mellitus (DM), with a direct correlation be…
View article: The Impact of Type II Diabetes Mellitus on Non-surgical Periodontal Treatment: A Non-randomized Clinical Trial
The Impact of Type II Diabetes Mellitus on Non-surgical Periodontal Treatment: A Non-randomized Clinical Trial Open
Background/Objectives: Periodontitis (P), a chronic inflammatory condition that affects the supportive tissues around the teeth, is 3 to 4 times more prevalent in individuals with diabetes mellitus (DM), with a direct correlation between i…
View article: Validation in a Brazilian population of gene markers of periodontitis previously investigated by GWAS and bioinformatic studies
Validation in a Brazilian population of gene markers of periodontitis previously investigated by GWAS and bioinformatic studies Open
Background: Bioinformatic tools and genome-wide association studies (GWAS) have led to comprehensive identification of single nucleotide polymorphisms (SNPs) associated with periodontitis in diverse populations. Here we aimed to detect and…
View article: The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study
The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study Open
Recent evidence suggests an association between hypertension and periodontitis, although the pathways and implications underlying both chronic conditions are still poorly understood. Therefore, the aim of this study was to evaluate the rel…
View article: The Effect of Non-Surgical Periodontal Treatment on Patients with Combined Refractory Arterial Hypertension and Stage III, Grade B Periodontitis: A Preliminary Prospective Clinical Study
The Effect of Non-Surgical Periodontal Treatment on Patients with Combined Refractory Arterial Hypertension and Stage III, Grade B Periodontitis: A Preliminary Prospective Clinical Study Open
We sought to evaluate the effects of non-surgical periodontal treatment (NSPT) on periodontal clinical parameters, systemic blood pressure (BP), and plasma levels of systemic inflammation markers in patients with combined refractory arteri…
View article: The Effect of Non-surgical Periodontal Treatment on Patients With Combined Refractory Arterial Hypertension and Stage Iii, Grade B Periodontitis: A Preliminary Prospective Clinical Study
The Effect of Non-surgical Periodontal Treatment on Patients With Combined Refractory Arterial Hypertension and Stage Iii, Grade B Periodontitis: A Preliminary Prospective Clinical Study Open
We sought to evaluate the effects of non-surgical periodontal treatment (NSPT) on periodontal clinical parameters, systemic blood pressure (BP) and plasma levels of systemic inflammation markers in patients with combined refractory arteria…
View article: Evidence Linking PPARG Genetic Variants with Periodontitis and Type 2 Diabetes Mellitus in a Brazilian Population
Evidence Linking PPARG Genetic Variants with Periodontitis and Type 2 Diabetes Mellitus in a Brazilian Population Open
The peroxisome proliferator-activated receptor gamma (PPARG) gene encodes a transcription factor involved in the regulation of complex metabolic and inflammatory diseases. We investigated whether single nucleotide polymorphisms (SNPs) and …
View article: Evidence Linking PPARG Genetic Variants with Periodontitis and Type 2 Diabetes Mellitus in a Brazilian Population
Evidence Linking PPARG Genetic Variants with Periodontitis and Type 2 Diabetes Mellitus in a Brazilian Population Open
The peroxisome proliferator-activated receptor gamma (PPARG) gene encodes a transcription factor involved in the regulation of complex metabolic and inflammatory diseases. We investigated whether single nucleotide polymorphisms (SNPs) and …
View article: Effect of Bacterial Infection on Ghrelin Receptor Regulation in Periodontal Cells and Tissues
Effect of Bacterial Infection on Ghrelin Receptor Regulation in Periodontal Cells and Tissues Open
The effect of bacterial infection on the expression of growth hormone secretagogue receptor (GHS-R) was investigated in periodontal cells and tissues, and the actions of ghrelin were evaluated. GHS-R was assessed in periodontal tissues of …
View article: Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects’ Periodontal, Glycemic, and Lipid Profiles
Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects’ Periodontal, Glycemic, and Lipid Profiles Open
Background. Type 2 diabetes mellitus (T2DM) and periodontitis (P) commonly occur as comorbidities, but the commonalities in the genetic makeup of affected individuals is largely unknown. Since dyslipidemia is a frequent condition in these …
View article: Effect of electric, ultrasonic and manual toothbrushes on biofilm removal and gingivitis control
Effect of electric, ultrasonic and manual toothbrushes on biofilm removal and gingivitis control Open
Aim: To evaluate the effect of manual (M), electric (E) and ultrasonic (US) toothbrushes on the removal of oral biofilm and control of gingivitis. Also, the roughness and tooth wear production were evaluated in vitro. Methods: For the in v…
View article: Validation in a Brazilian population of gene markers of periodontitis previously investigated by GWAS and bioinformatic studies
Validation in a Brazilian population of gene markers of periodontitis previously investigated by GWAS and bioinformatic studies Open
Background Bioinformatic tools and genome‐wide association studies (GWAS) have led to comprehensive identification of single nucleotide polymorphisms (SNPs) associated with periodontitis in diverse populations. Here we aimed to detect and …
View article: Genetic polymorphisms in the <i>Interleukins IL1B, IL4,</i> and <i>IL6</i> are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients
Genetic polymorphisms in the <i>Interleukins IL1B, IL4,</i> and <i>IL6</i> are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients Open
Objective To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A, IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes, “classically” related with periodontitis, could be associated with susceptibility to T2DM, and also wit…
View article: Absolute quantification of Aggregatibacter actinomycetemcomitans in patients carrying haplotypes associated with susceptibility to chronic periodontitis: multifaceted evaluation with periodontitis covariants
Absolute quantification of Aggregatibacter actinomycetemcomitans in patients carrying haplotypes associated with susceptibility to chronic periodontitis: multifaceted evaluation with periodontitis covariants Open
This study aimed to evaluate the association between haplotypes in the interleukin 8 (IL8) and IL4 genes previously associated to chronic periodontitis (CP) and the levels of Aggregatibacter actinomycetemcomitans (A.a.) in subgingival site…
View article: Expression Profile of Genes Potentially Associated with Adequate Glycemic Control in Patients with Type 2 Diabetes Mellitus
Expression Profile of Genes Potentially Associated with Adequate Glycemic Control in Patients with Type 2 Diabetes Mellitus Open
Despite increasing research in type 2 diabetes mellitus (T2D), there are few studies showing the impact of the poor glycemic control on biological processes occurring in T2D. In order to identify potential genes related to poorly/well-cont…