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View article: Geriatrische Forschung in Deutschland: Herausforderungen und Chancen – Erkenntnisse aus der GERisearch-Umfrage
Geriatrische Forschung in Deutschland: Herausforderungen und Chancen – Erkenntnisse aus der GERisearch-Umfrage Open
Zusammenfassung Hintergrund Für exzellente Altersforschung und die Weiterentwicklung der Geriatrie braucht es Ärztinnen und Ärzte, die sowohl klinisch als auch wissenschaftlich aktiv sind. Ziel Untersuchung der Forschungsaktivität, -intere…
View article: KlimaNot – Effects of climate change on emergency and acute care: protocol for a mixed-methods study (Preprint)
KlimaNot – Effects of climate change on emergency and acute care: protocol for a mixed-methods study (Preprint) Open
BACKGROUND Due to climate change, the population and healthcare systems face an increasing burden of weather-related health risks. Emergency departments (ED) are one of the first points of contact for acute and emergency care and insights…
View article: Chronic Pruritus in Geriatric Inpatients: Implementation of a guideline-compliant basic topical therapy
Chronic Pruritus in Geriatric Inpatients: Implementation of a guideline-compliant basic topical therapy Open
Purpose Chronic pruritus (CP) is a common condition in older adults, affecting quality of life. However, data on CP in hospitalised geriatric populations is scarce, especially in Germany. This study aims to address this by examining the pr…
View article: Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients
Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients Open
Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,…
View article: Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients
Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients Open
Aims Phenoconversion, a genotype‐phenotype mismatch, challenges a successful implementation of personalized medicine. The aim of this study was to detect and determine phenoconversion using the solanidine metabolites 3,4‐seco‐solanidine‐3,…
View article: Electrical Impedance Myography Quantifies Holding and Pushing During Isometric Muscle Contractions
Electrical Impedance Myography Quantifies Holding and Pushing During Isometric Muscle Contractions Open
For frequencies below the intersection point of the Nyquist plots of the muscle at rest and under contraction ${f} \leq {f}_{x}$ , the resistance and reactance are sensitive to the effects of muscle activity, with a strong Pearson correlat…
View article: Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial
Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial Open
Purpose During hospitalization, circadian rhythms and sleep are often disrupted, which has negative effects on health outcomes. Therefore, we aimed to investigate whether a daylight intervention in the morning could improve the circadian r…
View article: Older patients with vertebral and pelvic fractures: Study protocol of a clinical cohort
Older patients with vertebral and pelvic fractures: Study protocol of a clinical cohort Open
Background Vertebral and pelvic fractures are associated with a significant burden of negative health and psychosocial outcomes. The number of vertebral and pelvic fractures is increasing in an aging society. Vertebral and pelvic fractures…
View article: Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial
Effects of a daylight intervention in the morning on circadian rhythms and sleep in geriatric patients: a randomized crossover trial Open
PURPOSE: During hospitalization, circadian rhythms and sleep are often disrupted, which has negative effects on health outcomes. Therefore, we aimed to investigate whether a daylight intervention in the morning could improve the circadian …
View article: Movement patterns during gait initiation in older adults with various stages of frailty: a biomechanical analysis
Movement patterns during gait initiation in older adults with various stages of frailty: a biomechanical analysis Open
Background Gait initiation is challenging for older individuals with poor physical function, particularly for those with frailty. Frailty is a geriatric syndrome associated with increased risk of illness, falls, and functional decline. Thi…
View article: How age and health status impact attitudes towards aging and technologies in care: a quantitative analysis
How age and health status impact attitudes towards aging and technologies in care: a quantitative analysis Open
Background Increasing proportions of geriatric patients pose tremendous challenges for our society. Developments in assistive technologies have the potential to support older and frail people in aging and care. To reach a sustainable adopt…
View article: Does listening to audiobooks affect gait behavior?
Does listening to audiobooks affect gait behavior? Open
Background The effect of listening to audiobooks, podcasts, and other audio files while walking on gait performance has not been well studied. Although the number of audio users is growing annually. Evidence suggests that a posture-first s…
View article: Optimized Refeeding vs. Standard Care in Malnourished Older Hospitalized Patients: A Prospective, Non-Randomized Cluster-Controlled Study in Geriatric Acute Care
Optimized Refeeding vs. Standard Care in Malnourished Older Hospitalized Patients: A Prospective, Non-Randomized Cluster-Controlled Study in Geriatric Acute Care Open
Malnutrition is a prevalent geriatric syndrome with adverse health outcomes. This study aimed to assess the effectiveness of an optimized protocol for treatment of malnutrition in older hospitalized patients. We conducted a prospective, no…
View article: Does listening to audiobooks affect gait behavior?
Does listening to audiobooks affect gait behavior? Open
Background: The effect of listening to audiobooks, podcasts, and other audio files while walking on gait performance has not been well studied. Although the number of audio users is growing annually. Evidence suggests that a posture-first …
View article: Sex-Specific Associations between Serum IL-16 Levels and Sarcopenia in Older Adults
Sex-Specific Associations between Serum IL-16 Levels and Sarcopenia in Older Adults Open
Epidemiological studies of older adults have suggested a differential sex-specific prevalence of sarcopenia, which is a condition characterized by a progressive loss of skeletal muscle mass and function. Recently, we collected serum sample…
View article: Assessment of psychological and physical stressors among nurses in different functional areas before and during the COVID-19 pandemic: a cross-sectional study
Assessment of psychological and physical stressors among nurses in different functional areas before and during the COVID-19 pandemic: a cross-sectional study Open
Background The COVID-19 (coronavirus disease) pandemic placed a great burden on all health-care resources, especially nurses. The prevalence and underlying risk factors of affective symptoms related to the COVID-19 pandemic have been studi…
View article: Associations of Serum CXCL12α and CK Levels with Skeletal Muscle Mass in Older Adults
Associations of Serum CXCL12α and CK Levels with Skeletal Muscle Mass in Older Adults Open
Sarcopenia, a condition characterized by gradual loss of skeletal muscle mass and function, is a complex diagnosis; the decisive criterion in this diagnosis is the measurement of appendicular skeletal muscle index (ASMI). To identify poten…
View article: Spatiotemporal gait parameters in young individuals wearing an age simulation suit compared to healthy older individuals
Spatiotemporal gait parameters in young individuals wearing an age simulation suit compared to healthy older individuals Open
View article: Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression
Short-term zinc supplementation of zinc-deficient seniors counteracts CREMα - mediated IL-2 suppression Open
Background Aging is accompanied by a dramatic decline in the interleukin (IL)-2 production capacity of human immune cells, thus making seniors more susceptible to a variety of age-related diseases. A common cause of impaired cytokine produ…
View article: Keeping in step with the young: Chronometric and kinematic data show intact procedural locomotor sequence learning in older adults
Keeping in step with the young: Chronometric and kinematic data show intact procedural locomotor sequence learning in older adults Open
Sequence learning in serial reaction time tasks (SRTT) is an established, lab-based experimental paradigm to study acquisition and transfer of skill based on the detection of predictable stimulus and motor response sequences. Sequence lear…
View article: Insights Into the Older Adults' World: Concepts of Aging, Care, and Using Assistive Technology in Late Adulthood
Insights Into the Older Adults' World: Concepts of Aging, Care, and Using Assistive Technology in Late Adulthood Open
The ongoing demographic change forces different stakeholders to cope with increasing needs in nursing care and the economic costs. Consequences arising from the population aging can be supported by assistive technologies to maintain older …
View article: Implementation of a telemedicine geriatric co-evaluation in the emergency department: a prospective pilot study
Implementation of a telemedicine geriatric co-evaluation in the emergency department: a prospective pilot study Open
INTRODUCTION Complex drug management is a common challenge in the treatment of geriatric patients. Pandemic scenarios, such as the current one (COVID-19), call for a reduction of face-to-face meetings, especially for elderly patients. Ther…
View article: Reducing Loneliness in Stationary Geriatric Care with Robots and Virtual Encounters—A Contribution to the COVID-19 Pandemic
Reducing Loneliness in Stationary Geriatric Care with Robots and Virtual Encounters—A Contribution to the COVID-19 Pandemic Open
The bans on visiting nursing homes during the COVID-19 pandemic, while intended to protect residents, also have the risk of increasing the loneliness and social isolation that already existed among the older generations before the pandemic…
View article: Management of a Hospital-Wide COVID-19 Outbreak Affecting Patients and Healthcare Workers
Management of a Hospital-Wide COVID-19 Outbreak Affecting Patients and Healthcare Workers Open
View article: How Age and Health Status Impact Attitudes towards Aging and Technologies in Care: A Quantitative Study (Preprint)
How Age and Health Status Impact Attitudes towards Aging and Technologies in Care: A Quantitative Study (Preprint) Open
View article: COVID-19 EPIDEMIC IN THE NURSING HOME – THE GERMAN EXPERIENCE
COVID-19 EPIDEMIC IN THE NURSING HOME – THE GERMAN EXPERIENCE Open
View article: Walking with rollator: a systematic review of gait parameters in older persons
Walking with rollator: a systematic review of gait parameters in older persons Open
View article: Long-Chain Fatty Acids and Inflammatory Markers Coaccumulate in the Skeletal Muscle of Sarcopenic Old Rats
Long-Chain Fatty Acids and Inflammatory Markers Coaccumulate in the Skeletal Muscle of Sarcopenic Old Rats Open
Obesity and inflammation are reportedly associated with the pathogenesis of sarcopenia, which is characterized by age-related loss of skeletal muscle mass. Intramuscular fat deposits have been found to compromise muscle integrity; however,…
View article: High-fat diet-induced obesity causes an inflammatory microenvironment in the kidneys of aging Long-Evans rats
High-fat diet-induced obesity causes an inflammatory microenvironment in the kidneys of aging Long-Evans rats Open