Explanipedia

Patient experiences, attitudes, and profiles regarding artificial intelligence in rheumatology: a German national cross-sectional survey study Open

Hannah Labinsky, Philipp Klemm, Lukas Graalmann, Thea Thiele, Johannes Hornig , et al. · 2025

While artificial intelligence (AI) is gaining attention in rheumatology, little is known about patient perspectives. This study addresses this gap by examining patients’ experiences and attitudes toward AI. A nationwide, cross-sectional, w…

POS0499 CARE SITUATION OF GERMAN PATIENTS WITH IgG4-RELATED DISEASE - FIRST EXCERPTS FROM THE GERMAN LüRIgG-4 REGISTRY Open

Thea Thiele, Marc Phillipp Silchmüller, Lauren Risser, L. Graalmann, Steffen Hirsch , et al. · 2025

Prevalence of comorbid autoimmune diseases and antibodies in newly diagnosed multiple sclerosis patients Open

Konstantin Fritz Jendretzky, Lisa-Marie Lezius, Thea Thiele, Franz Felix Konen, André Huss , et al. · 2024

Background Diagnosing multiple sclerosis (MS) is challenging due to diverse symptoms and the absence of specific biomarkers. Concurrent autoimmune diseases (AID) or non-specific antibodies further complicate diagnosis, progression monitori…

JAK inhibitors to treat STAT3 gain-of-function: a single-center report and literature review Open

Faranaz Atschekzei, Stephan Traidl, Julia Carlens, Katharina Schütz, Sandra von Hardenberg , et al. · 2024

Objective The signal transducer and activator of transcription 3 (STAT3) gain-of-function (GOF) syndrome (STAT3-GOF) is an inborn error of immunity (IEI) characterized by diverse manifestations of immune dysregulation that necessitate syst…

Toll‐Like Receptor 8 is Expressed in Monocytes in Contrast to Plasmacytoid Dendritic Cells and Mediates Aberrant Interleukin‐10 Responses in Patients With Systemic Sclerosis Open

Christine Ehlers, Thea Thiele, Hannah Biermann, Stephan Traidl, Luzia Bruns , et al. · 2024

Objective Systemic sclerosis (SSc) is a severe rheumatic disease causing fibrotic tissue rearrangement. Aberrant toll‐like receptor (TLR) 8 transcripts in plasmacytoid dendritic cells (pDCs) were recently linked to SSc pathogenesis, which …

Die Subanalyse von Rheuma-VOR zeigt den erheblichen Bedarf der rheumatologischen Versorgung auf Open

Stefanie Hirsch, Kirsten Hoeper, Dirk Meyer‐Olson, Andreas Schwarting, K. Gente , et al. · 2024

Treatment strategies in MDA5-positive clinically amyopathic dermatomyositis: a single-center retrospective analysis Open

Stefanie Hirsch, Gesa H. Pöhler, Benjamin Seeliger, Antje Prasse, Torsten Witte , et al. · 2024

Melanoma differentiation-associated protein 5 (MDA5) antibody positive amyopathic dermatomyositis (DM) is a rare inflammatory disease. So far, there is no official treatment guideline in MDA5 amyopathic dermatomyositis, but early and aggre…

The Pet-Pain Study: How Caring for a Dog Affects Quality of Life, Pain, and Depression in Patients With Inflammatory Arthritis Open

Thea Thiele, Carl Christoph Pott, Gerrit Ahrenstorf, Torsten Witte, Stefanie Hirsch · 2023

Treatment options for rheumatoid arthritis (RA), spondyloarthritis (SpA) and psoriatic arthritis (PsA) have improved with the introduction of biologic and targeted synthetic disease-modifying antirheumatic drugs.Although a good clinical re…

Identification of variants in genes associated with autoinflammatory disorders in a cohort of patients with psoriatic arthritis Open

Faranaz Atschekzei, Natalia Dubrowinskaja, Manfred Anim, Thea Thiele, Torsten Witte , et al. · 2022

Objectives Besides adaptive immunity genes, genetic risk factors for psoriatic arthritis (PsA) include innate immunity loci, which suggests an autoinflammatory disease mechanism, at least in a subset of patients. Here, we aimed at investig…

[Care of rheumatology patients during the lockdown in early 2020 : Telemedicine, delegation, patient satisfaction and vaccination behavior]. Open

Thea Thiele, S. Beider, Henrik Kühl, G. Mielke, Anna Holz , et al. · 2022

Nerve ultrasound findings in Sjögren's syndrome‐associated neuropathy Open

Tabea Seeliger, Lena Bönig, Stefan Gingele, Nils Prenzler, Thea Thiele , et al. · 2021

Background and Purpose The phenotype of Sjögren's syndrome‐associated neuropathy has been better characterized in recent years. However, Sjögren's syndrome‐associated neuropathy remains an underdiagnosed entity with only few insights consi…

Versorgung von rheumatologischen Patienten während des Lockdowns im Frühjahr 2020 Open

Thea Thiele, S. Beider, Henrik Kühl, G. Mielke, Anna Holz , et al. · 2021

Multidrug-resistant Mycobacterium tuberculosis: a report of cosmopolitan microbial migration and an analysis of best management practices Open

Oana Joean, Thea Thiele, Katharina Schütz, Nicolaus Schwerk, Ludwig Sedlacek , et al. · 2020

Strategic Anti-SARS-CoV-2 Serology Testing in a Low Prevalence Setting: The COVID-19 Contact (CoCo) Study in Healthcare Professionals Open

Georg M. N. Behrens, Anne Cossmann, Metodi V. Stankov, Bianca Schulte, Hendrik Streeck , et al. · 2020

Hearing dysfunction in patients with Neuro-Sjögren: a cross-sectional study Open

Tabea Seeliger, Lena Bönig, Torsten Witte, Thea Thiele, Anke Lesinski‐Schiedat , et al. · 2020

In conclusion, our results show that hearing dysfunction as a possible consequence of cranial neuropathy in patients with Neuro-Sjögren has been underestimated in previous studies.

Strategic anti-SARS-CoV-2 serology testing in a low prevalence pandemic: The COVID-19 Contact (CoCo) Study in health care professionals Open

Georg M. N. Behrens, Anne Cossmann, Metodi V. Stankov, Bianca Schulte, Hendrik Streeck , et al. · 2020

Background Serology testing is explored for epidemiological research and to inform individuals after suspected infection. During the COVID-19 pandemic, frontline healthcare professionals (HCP) may be at particular risk for infection. No lo…

Lung Involvement in Primary Sjögren's Syndrome—An Under-Diagnosed Entity Open

Georgios Sogkas, Stefanie Hirsch, Karen M. Olsson, Jan B. Hinrichs, Thea Thiele , et al. · 2020

Interstitial lung disease (ILD) represents a frequent extra-glandular manifestation of primary Sjögren's Syndrome (pSS). Limited published data regarding phenotyping and treatment exists. Advances in managing specific ILD phenotypes have n…

Cognitive impairment in patients with Neuro‐Sjögren Open

Tabea Seeliger, Lena Jacobsen, Merle K. Hendel, Lena Bönig, Nils Prenzler , et al. · 2020

Objective Extraglandular neurological manifestations of Sjögren’s syndrome are increasingly recognized, defining the disease entity of Neuro‐Sjögren. Neuropsychological assessment of patients with Sjögren’s syndrome has hitherto been perfo…

Clinical, Radiological, and Laboratory Features of Spinal Cord Involvement in Primary Sjögren’s Syndrome Open

Michaela Butryn, Jens Neumann, Leoni Rolfes, Claudius Bartels, Mike P. Wattjes , et al. · 2020

Objective: To identify radiological and laboratory hallmarks in patients with primary Sjögren’s syndrome (pSS) presenting with spinal cord involvement. Methods: Clinical and laboratory routine parameters were analyzed in a retrospective mu…

Neuro-Sjögren: Peripheral Neuropathy With Limb Weakness in Sjögren's Syndrome Open

Tabea Seeliger, Nils Prenzler, Stefan Gingele, Benjamin Seeliger, Sonja Körner , et al. · 2019

Objective: Sjögren's syndrome is a heterogeneous inflammatory disorder frequently involving peripheral nerves with a wide spectrum of sensory modalities and distribution patterns. The objective of this cross-sectional study was to d…

Take a Second Look: It's Kikuchi’s Disease! A Case Report and Review of Literature Open

Oana Joean, Thea Thiele, Mieke Raap, Reinhold E. Schmidt, Matthias Stoll · 2018

Generalized lymphadenopathy is a common cause of concern for both patients and clinicians. Possible etiologies include infections, malignancies and autoimmune diseases. Kikuchi Fujimoto disease (KFD) is a hyperergic condition that presents…

Niedrige Raten einer Infektion mit Helicobacter pylori bei Transplantationspatienten mit gastroduodenaler Ulkuskrankheit Open

Thea Thiele · 2018

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