Theodore Plappert
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View article: Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma
Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma Open
Objective We sought to determine how sex and dexrazoxane therapy influence cardiac remodelling in children with sarcoma receiving high-dose doxorubicin. Methods In a retrospective cohort of 85 children with sarcoma receiving high-dose doxo…
View article: Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma
Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma Open
Background: Sunitinib, used widely in metastatic renal cell carcinoma, can result in hypertension, left ventricular dysfunction, and heart failure. However, the relationships between vascular function and cardiac dysfunction with sunitinib…
View article: Detailed Echocardiographic Phenotyping in Breast Cancer Patients
Detailed Echocardiographic Phenotyping in Breast Cancer Patients Open
Background: Cardiovascular disease in patients with breast cancer is of growing concern. The longitudinal effects of commonly used therapies, including doxorubicin and trastuzumab, on cardiac remodeling and function remain unknown in this …