Tom C. Nguyen
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View article: Endo-Wheat for ascending aortic intramural hematoma: Endo-Wheat versus endo-Bentall
Endo-Wheat for ascending aortic intramural hematoma: Endo-Wheat versus endo-Bentall Open
View article: Obesity Selectively Increases Intraoperative Risk in Left-Sided Colon Cancer Surgery: A Retrospective Cohort Study
Obesity Selectively Increases Intraoperative Risk in Left-Sided Colon Cancer Surgery: A Retrospective Cohort Study Open
Background Obesity is traditionally viewed as a risk factor for adverse surgical outcomes. This study evaluated whether obesity (BMI ≥ 30 kg/m 2 ) independently affected intraoperative and postoperative outcomes following colon cancer rese…
View article: Intrinsic <scp>PDL1</scp> Signaling Modulates <scp>TGFBI</scp>‐Mediated Growth Suppression in Lung Adenocarcinoma
Intrinsic <span>PDL1</span> Signaling Modulates <span>TGFBI</span>‐Mediated Growth Suppression in Lung Adenocarcinoma Open
Programmed death ligand 1 (PDL1) suppresses T‐cell immunity by engaging programmed cell death protein 1 (PD1), and its blockade can activate T‐cell responses. Although PDL1 is a transmembrane protein, its intrinsic signaling role in regula…
View article: Endoscopic mitral valve surgery: picture from the real world—sub-analysis from the Mini-Mitral International Registry
Endoscopic mitral valve surgery: picture from the real world—sub-analysis from the Mini-Mitral International Registry Open
View article: Neoadjuvant Therapy in Locally Advanced Colon Cancer: A Case for Selective Adoption in <scp>pMMR</scp> and Transformation in <scp>dMMR</scp>
Neoadjuvant Therapy in Locally Advanced Colon Cancer: A Case for Selective Adoption in <span>pMMR</span> and Transformation in <span>dMMR</span> Open
View article: Utilization of minimally invasive approaches for transcatheter aortic valve replacement explant: when and how?
Utilization of minimally invasive approaches for transcatheter aortic valve replacement explant: when and how? Open
View article: Tumor Immunophenotypic Correlates in Patients Aged 80 Years or Older with Non-Small Cell Lung Cancer and Outcomes to First-Line Pembrolizumab in Pd-L1 High (≥50%) Patients
Tumor Immunophenotypic Correlates in Patients Aged 80 Years or Older with Non-Small Cell Lung Cancer and Outcomes to First-Line Pembrolizumab in Pd-L1 High (≥50%) Patients Open
View article: Impact of Complex Anatomy and Patient Risk Profile in Minimally Invasive Mitral Valve Surgery
Impact of Complex Anatomy and Patient Risk Profile in Minimally Invasive Mitral Valve Surgery Open
View article: Savings associated with surgical aortic valve replacement with a RESILIA tissue valve based on seven-year COMMENCE trial results
Savings associated with surgical aortic valve replacement with a RESILIA tissue valve based on seven-year COMMENCE trial results Open
Patients receiving RESILIA tissue valves are projected to have lower SAVR-related health expenditures relative to mechanical and legacy tissue valves.
View article: Transcatheter Bailout: An Important Option During Complex Aortic Surgery
Transcatheter Bailout: An Important Option During Complex Aortic Surgery Open
This report presents the case of a 66-year-old man with acute torrential aortic insufficiency after a Ross procedure 20 years earlier, a biologic aortic valve replacement 16 years earlier, and a transcatheter valve-in-valve 4 years earlier…
View article: Minimally invasive aortic valve replacement with Y-incision aortic root enlargement
Minimally invasive aortic valve replacement with Y-incision aortic root enlargement Open
View article: Lessons Learned From TranslateCovid, a Multilingual Online Resource Hub for Asian American and Pacific Islander Communities and Beyond
Lessons Learned From TranslateCovid, a Multilingual Online Resource Hub for Asian American and Pacific Islander Communities and Beyond Open
The COVID-19 pandemic exacerbated health disparities among immigrant communities. Delivering accurate information and addressing misinformation on protective measures and vaccination to linguistically disadvantaged groups was critical for …
View article: Clinical Improvement With Transcatheter Edge-to-Edge Tricuspid Repair Irrespective of Right Atrial Pressure
Clinical Improvement With Transcatheter Edge-to-Edge Tricuspid Repair Irrespective of Right Atrial Pressure Open
View article: Improving Patient Outcomes with a Mobile Digital Health Platform for Patients Undergoing Transcatheter Aortic Valve Replacement
Improving Patient Outcomes with a Mobile Digital Health Platform for Patients Undergoing Transcatheter Aortic Valve Replacement Open
In this non-randomized, retrospective study, we found significant decreases in 90-day readmissions, ER visits, and complications in TAVR patients using an app compared to traditional care. By engaging patients throughout their intervention…
View article: Impact of transcatheter heart valve type on outcomes of surgical explantation after failed transcatheter aortic valve replacement: the EXPLANT-TAVR international registry
Impact of transcatheter heart valve type on outcomes of surgical explantation after failed transcatheter aortic valve replacement: the EXPLANT-TAVR international registry Open
In the EXPLANT-TAVR global registry, BEV and SEV groups had different indications for surgical explantation, with more root replacements in SEV failure, but no differences in midterm mortality and morbidities. Further refinement of TAVR ex…
View article: Discussion to: New approach to the mitral valve through the left anterior minithoracotomy for combined valve and coronary surgical procedures
Discussion to: New approach to the mitral valve through the left anterior minithoracotomy for combined valve and coronary surgical procedures Open
View article: Pacemaker implantation after concomitant tricuspid valve repair in patients undergoing minimally invasive mitral valve surgery: Results from the Mini-Mitral International Registry
Pacemaker implantation after concomitant tricuspid valve repair in patients undergoing minimally invasive mitral valve surgery: Results from the Mini-Mitral International Registry Open
View article: Appropriateness of concomitant surgical ablation for atrial fibrillation during redo cardiac surgery
Appropriateness of concomitant surgical ablation for atrial fibrillation during redo cardiac surgery Open
Concomitant surgical ablation (SA) results in increased freedom from atrial fibrillation (AF) of patients undergoing cardiac surgery without additional operative risk of mortality or major morbidity, and is recommended at the time of conco…
View article: Neurological outcomes in minimally invasive mitral valve surgery: risk factors analysis from the Mini-Mitral International Registry
Neurological outcomes in minimally invasive mitral valve surgery: risk factors analysis from the Mini-Mitral International Registry Open
OBJECTIVES The aim of this study was to examine the incidence and predictors of stroke after minimally invasive mitral valve surgery (mini-MVS) and to assess the role of preoperative CT scan on surgical management and neurological outcomes…
View article: Mini-mitral simulation simplified
Mini-mitral simulation simplified Open
Glossary of abbreviations: IRB (institutional review board), MIMVR (minimally invasive mitral valve repair), LA (left atriotomy), LV (left ventricular) Central picture legend: Foam template facilitates practice of all steps of minimally in…
View article: Attending your first academic cardiothoracic conference: Comprehensive guide for trainees and students
Attending your first academic cardiothoracic conference: Comprehensive guide for trainees and students Open
View article: Digital Health for Patients Undergoing Cardiac Surgery: A Systematic Review
Digital Health for Patients Undergoing Cardiac Surgery: A Systematic Review Open
Digital health interventions have shown promise in improving patient outcomes and experiences in various healthcare settings. However, their effectiveness in the context of cardiac surgery remains uncertain. This systematic review aims to …
View article: Looking towards the future: patient-specific computational modeling to optimize outcomes for transcatheter mitral valve repair
Looking towards the future: patient-specific computational modeling to optimize outcomes for transcatheter mitral valve repair Open
Severe mitral valve regurgitation (MR) is a heart valve disease that progresses to end-stage congestive heart failure and death if left untreated. Surgical repair or replacement of the mitral valve (MV) remains the gold standard for treatm…
View article: Aortic cross-clamp time correlates with mortality in the mini-mitral international registry
Aortic cross-clamp time correlates with mortality in the mini-mitral international registry Open
OBJECTIVES Minimally invasive access has become the preferred choice in mitral and/or tricuspid valve surgery. Reported outcomes are at least similar to classic sternotomy although aortic cross-clamp times are usually longer. METHODS We an…
View article: Table S1 from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
Table S1 from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer Open
SgRNAs, primers, and antibodies used in this study
View article: Supplementary Data from Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC
Supplementary Data from Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC Open
Supplementary Figures
View article: Table S3 from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
Table S3 from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer Open
Post-baseline toxicity incidence.
View article: Supplementary Data from Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC
Supplementary Data from Molecular Mechanisms of Acquired Resistance to MET Tyrosine Kinase Inhibitors in Patients with MET Exon 14–Mutant NSCLC Open
Supplementary Figure Legends
View article: Table S2 from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
Table S2 from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer Open
Demographics of study participants.
View article: Figure S1: CONSORT diagram. from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
Figure S1: CONSORT diagram. from Identification of a RAS-activating <i>TMEM87A–RASGRF1</i> Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer Open
Thirteen patients were enrolled and underwent at least one cycle of therapy.