Thibaut Gauvrit
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View article: Upregulation of adenosine A2A receptor in astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits
Upregulation of adenosine A2A receptor in astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits Open
View article: Upregulation of adenosine A2A receptor by astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits.
Upregulation of adenosine A2A receptor by astrocytes is sufficient to trigger hippocampal multicellular dysfunctions and memory deficits. Open
Adenosine is an ubiquitous neuromodulator that ensures cerebral homeostasis. It exerts numerous functions through the activation of G-protein-coupled adenosine receptors (ARs), in particular A1 (A1R) and A2A
View article: Consequences of a maternal high fat diet during lactation on offspring in a mouse model of tauopathy
Consequences of a maternal high fat diet during lactation on offspring in a mouse model of tauopathy Open
De nombreuses études indiquent qu'une perturbation de l'environnement périnatal contribuerait au développement de maladies chez les descendants adultes. La perturbation la plus étudiée est la malnutrition qui touche plus de 2 milliards d'i…
View article: Multi-Omics Data Integration Reveals Sex-Dependent Hippocampal Programming by Maternal High-Fat Diet during Lactation in Adult Mouse Offspring
Multi-Omics Data Integration Reveals Sex-Dependent Hippocampal Programming by Maternal High-Fat Diet during Lactation in Adult Mouse Offspring Open
Early-life exposure to high-fat diets (HF) can program metabolic and cognitive alterations in adult offspring. Although the hippocampus plays a crucial role in memory and metabolic homeostasis, few studies have reported the impact of mater…
View article: Multi-Omics Data Integration Reveals Sex-Dependent Hippocampal Programming by Maternal High-Fat Diet during Lactation in Adult Mouse Offspring
Multi-Omics Data Integration Reveals Sex-Dependent Hippocampal Programming by Maternal High-Fat Diet during Lactation in Adult Mouse Offspring Open
Early-life exposure to high-fat diet (HF) can program metabolic and cognitive alterations in adult offspring. Although the hippocampus plays a crucial role in memory and metabolic homeostasis, few studies reported the impact of maternal HF…
View article: Early-Life Environment Influence on Late-Onset Alzheimer’s Disease
Early-Life Environment Influence on Late-Onset Alzheimer’s Disease Open
With the expand of the population’s average age, the incidence of neurodegenerative disorders has dramatically increased over the last decades. Alzheimer disease (AD) which is the most prevalent neurodegenerative disease is mostly sporadic…
View article: Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model
Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model Open
Alzheimer’s disease (AD) is the leading cause of dementia. While impaired glucose homeostasis has been shown to increase AD risk and pathological loss of tau function, the latter has been suggested to contribute to the emergence of the glu…
View article: P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy
P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy Open