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View article: Predictive factors for the detection of occult metastases during staging laparoscopy in patients with gastric carcinoma and adenocarcinoma of the esophagogastric junction
Predictive factors for the detection of occult metastases during staging laparoscopy in patients with gastric carcinoma and adenocarcinoma of the esophagogastric junction Open
Introduction Peritoneal metastasis can occur in all stages of gastric cancer (GC) and adenocarcinoma of the esophagogastric junction (AEG) but staging laparoscopy (SL) is recommended for advanced stages. This study aimed to evaluate predic…
View article: Effectiveness and feasibility of short-course simulator training for robotic surgery novices – a randomized controlled trial (FastSim trial)
Effectiveness and feasibility of short-course simulator training for robotic surgery novices – a randomized controlled trial (FastSim trial) Open
Objectives As robot-assisted surgery (RAS) is on the rise, feasible and effective simulator training for surgical residents is needed. This study compares the effectiveness and feasibility of two compact simulator training protocols on the…
View article: Perioperative interdisciplinary optimisation of patients with heart failure undergoing non-cardiac surgery with intermediate or high surgical risk: the rationale and study protocol for the multicentre, randomised interventional PeriOP-CARE HF trial
Perioperative interdisciplinary optimisation of patients with heart failure undergoing non-cardiac surgery with intermediate or high surgical risk: the rationale and study protocol for the multicentre, randomised interventional PeriOP-CARE HF trial Open
Aim Chronic heart failure (HF) is a frequent comorbidity in elderly patients undergoing major non-cardiac surgery with increasing prevalence. This trial aims to evaluate a new interdisciplinary, multimodal and individually optimised treatm…
View article: Impact of Enhanced Recovery After Surgery Protocol Compliance on Outcome After Pancreatic Surgery: Results From a Certified ERAS Center
Impact of Enhanced Recovery After Surgery Protocol Compliance on Outcome After Pancreatic Surgery: Results From a Certified ERAS Center Open
Objective: The aim was to evaluate the sustainability of the pancreatic Enhanced Recovery After Surgery (ERAS) program and the effect of ERAS items on patient morbidity and hospital stay. Background: The current ERAS guideline recommendati…
View article: Impact of an enhanced anti-infection prophylaxis strategy for pancreatoduodenectomy: a single centre analysis
Impact of an enhanced anti-infection prophylaxis strategy for pancreatoduodenectomy: a single centre analysis Open
Introduction Surgical site infection (SSI) after pancreatoduodenectomy (PD) is a significant concern. Targeted antibiotic prophylaxis (pAP) has been tested to mitigate antibiotic resistance patterns, especially after preoperative bile duct…
View article: Preferences of patients and surgeons regarding counselling before pancreatectomy: 4PC trial
Preferences of patients and surgeons regarding counselling before pancreatectomy: 4PC trial Open
View article: Enhanced postoperative mobilization and biotracking after colorectal oncological resection (INTENSE) – study protocol for a randomized controlled trial
Enhanced postoperative mobilization and biotracking after colorectal oncological resection (INTENSE) – study protocol for a randomized controlled trial Open
Background: Enhanced recovery after surgery (ERAS) is a multimodal perioperative care pathway originally designed to minimize perioperative stress and accelerate postoperative recovery in patients undergoing colorectal surgery. Early mobil…
View article: Stratifying esophago-gastric cancer treatment using a patient-derived organoid-based threshold
Stratifying esophago-gastric cancer treatment using a patient-derived organoid-based threshold Open
View article: Case-Based Serious Gaming for Complication Management in Colorectal and Pancreatic Surgery: Prospective Observational Study
Case-Based Serious Gaming for Complication Management in Colorectal and Pancreatic Surgery: Prospective Observational Study Open
Background The potential risk and subsequent impact of serious complications after pancreatic and colorectal surgery can be significantly reduced through early recognition, correct assessment, and timely initiation of appropriate therapy. …
View article: Effects of early postoperative mobilization following gastrointestinal surgery: systematic review and meta-analysis
Effects of early postoperative mobilization following gastrointestinal surgery: systematic review and meta-analysis Open
Background Early postoperative mobilization is considered a key element of enhanced recovery after surgery protocols. The aim of this study was to summarize the effect of early postoperative mobilization following gastrointestinal operatio…
View article: Single chest drain is not inferior to double chest drain after robotic esophagectomy: a propensity score-matched analysis
Single chest drain is not inferior to double chest drain after robotic esophagectomy: a propensity score-matched analysis Open
Background Chest drain management has a significant influence on postoperative recovery after robot-assisted minimally invasive esophagectomy (RAMIE). The use of chest drains increases postoperative pain by irritating intercostal nerves an…
View article: Intraoperative minimally invasive left bronchial reconstruction using a pericardial flap during robot-assisted esophagectomy
Intraoperative minimally invasive left bronchial reconstruction using a pericardial flap during robot-assisted esophagectomy Open
Central MessageThe report demonstrates a minimally invasive repair of a left mainstem bronchus injury during robot-assisted minimally invasive esophagectomy using a pericardial flap and an uneventful course. The report demonstrates a minim…
View article: Drainless robot-assisted minimally invasive oesophagectomy—randomized controlled trial (RESPECT)
Drainless robot-assisted minimally invasive oesophagectomy—randomized controlled trial (RESPECT) Open
View article: Fast and label-free intraoperative discrimination of malignant pancreatic tissue by attenuated total reflection infrared spectroscopy
Fast and label-free intraoperative discrimination of malignant pancreatic tissue by attenuated total reflection infrared spectroscopy Open
Our study shows the possibility of applying fiber-based ATR IR spectroscopy in combination with a supervised classification model for rapid pancreatic tissue identification with a high potential for transfer into intraoperative surgical di…
View article: Analysis of predictors for postoperative complications after pancreatectomy––what is new after establishing the definition of postpancreatectomy acute pancreatitis (PPAP)?
Analysis of predictors for postoperative complications after pancreatectomy––what is new after establishing the definition of postpancreatectomy acute pancreatitis (PPAP)? Open
Purpose We aimed to analyze the predictive value of hyperamylasemia after pancreatectomy for morbidity and for the decision to perform rescue completion pancreatectomy (CP) in a retrospective cohort study. Methods Data were extracted from …
View article: Selective Decontamination of the Digestive Tract in Pancreatic Head Resections—A Propensity Score-Matched Analysis
Selective Decontamination of the Digestive Tract in Pancreatic Head Resections—A Propensity Score-Matched Analysis Open
(1) Background: The postoperative morbidity rate after pancreatic head resection remains high, partly due to infectious complications. The primary aim of this study was to analyze the influence of selective decontamination of the digestive…
View article: Case-Based Serious Gaming for Complication Management in Colorectal and Pancreatic Surgery: Prospective Observational Study (Preprint)
Case-Based Serious Gaming for Complication Management in Colorectal and Pancreatic Surgery: Prospective Observational Study (Preprint) Open
BACKGROUND The potential risk and subsequent impact of serious complications after pancreatic and colorectal surgery can be significantly reduced through early recognition, correct assessment, and timely initiation of appropriate therapy.…
View article: Robotic Esophagectomy Compared With Open Esophagectomy Reduces Sarcopenia within the First Postoperative Year: A Propensity Score-Matched Analysis
Robotic Esophagectomy Compared With Open Esophagectomy Reduces Sarcopenia within the First Postoperative Year: A Propensity Score-Matched Analysis Open
View article: How we do it—the use of peritoneal patches for reconstruction of vena cava inferior and portal vein in hepatopancreatobiliary surgery
How we do it—the use of peritoneal patches for reconstruction of vena cava inferior and portal vein in hepatopancreatobiliary surgery Open
Purpose Extended resections in hepatopancreatobiliary (HPB) surgery frequently require vascular resection to obtain tumor clearance. The use of alloplastic grafts may increase postoperative morbidity due to septic or thrombotic complicatio…
View article: Immunohistochemical analyses of paraffin-embedded sections after primary surgery or trimodality treatment in esophageal carcinoma
Immunohistochemical analyses of paraffin-embedded sections after primary surgery or trimodality treatment in esophageal carcinoma Open
View article: Label-free differentiation of human pancreatic cancer, pancreatitis, and normal pancreatic tissue by molecular spectroscopy
Label-free differentiation of human pancreatic cancer, pancreatitis, and normal pancreatic tissue by molecular spectroscopy Open
IR spectroscopy in combination with PCA and supervised classification is an efficient analytical method to reliably distinguish between benign and malignant pancreatic tissues. It opens up a wide research field for oncological and surgical…
View article: Diploid hepatocytes drive physiological liver renewal in adult humans
Diploid hepatocytes drive physiological liver renewal in adult humans Open
Physiological liver cell replacement is central to maintaining the organ's high metabolic activity, although its characteristics are difficult to study in humans. Using retrospective radiocarbon (14C) birth dating of cells, we r…
View article: Selective decontamination of the digestive tract in colorectal surgery reduces anastomotic leakage and costs: a propensity score analysis
Selective decontamination of the digestive tract in colorectal surgery reduces anastomotic leakage and costs: a propensity score analysis Open
View article: Robotic-assisted minimally invasive Ivor Lewis esophagectomy within the prospective multicenter German da Vinci Xi registry trial
Robotic-assisted minimally invasive Ivor Lewis esophagectomy within the prospective multicenter German da Vinci Xi registry trial Open
Purpose Robotic-assisted minimally invasive esophagectomy (RAMIE) has become one standard approach for the operative treatment of esophageal tumors at specialized centers. Here, we report the results of a prospective multicenter registry f…
View article: Quality of life and metabolic outcomes after total pancreatectomy and simultaneous islet autotransplantation
Quality of life and metabolic outcomes after total pancreatectomy and simultaneous islet autotransplantation Open
Background Pancreas surgery remains technically challenging and is associated with considerable morbidity and mortality. Identification of predictive risk factors for complications have led to a stratified surgical approach and postoperati…
View article: The Impact of Pancreatic Head Resection on Blood Glucose Homeostasis in Patients with Chronic Pancreatitis
The Impact of Pancreatic Head Resection on Blood Glucose Homeostasis in Patients with Chronic Pancreatitis Open
Background: Chronic pancreatitis (CP) often leads to recurrent pain as well as exocrine and/or endocrine pancreatic insufficiency. This study aimed to investigate the effect of pancreatic head resections on glucose metabolism in patients w…
View article: Strategiewechsel zur minimal-invasiven Ösophagektomie – Ergebnisse an einem zertifizierten Zentrum
Strategiewechsel zur minimal-invasiven Ösophagektomie – Ergebnisse an einem zertifizierten Zentrum Open
View article: Short-term preoperative drainage is associated with improved postoperative outcomes compared to that of long-term biliary drainage in pancreatic surgery
Short-term preoperative drainage is associated with improved postoperative outcomes compared to that of long-term biliary drainage in pancreatic surgery Open
View article: Comparative Analysis of Postoperative Complications after Cytoreductive Surgery and HIPEC in Gastric Cancer
Comparative Analysis of Postoperative Complications after Cytoreductive Surgery and HIPEC in Gastric Cancer Open
Introduction: Patients with advanced gastric cancer (AGC) frequently show peritoneal carcinomatosis (PC). PC reduces life expectancy and quality of life. Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemother…
View article: Influence of the First Wave of the COVID-19 Pandemic on Cancer Care in a German Comprehensive Cancer Center
Influence of the First Wave of the COVID-19 Pandemic on Cancer Care in a German Comprehensive Cancer Center Open
Introduction: During the first wave of the COVID-19 pandemic in 2020, the German government implemented legal restrictions to avoid the overloading of intensive care units by patients with COVID-19. The influence of these effects on diagno…