Thomas Althaus
YOU?
Author Swipe
View article: Towards the elimination of mother-to-child transmission of syphilis in the WHO European region: implications from a survey in the non-European Union and European economic area countries
Towards the elimination of mother-to-child transmission of syphilis in the WHO European region: implications from a survey in the non-European Union and European economic area countries Open
Globally, the public health burden of congenital syphilis (CS) remains high despite efforts to eliminate mother-to-child transmission (EMTCT) of syphilis and the fact that this disease is treatable if diagnosed early. In the WHO European R…
View article: Diagnostic accuracy of non-invasive SARS-CoV-2 screening tests: a national prospective analysis
Diagnostic accuracy of non-invasive SARS-CoV-2 screening tests: a national prospective analysis Open
NCT05074745. Registration date: 12-10-2021.
View article: Diagnostic accuracy of non-invasive SARS-CoV-2 screening tests: a national prospective analysis
Diagnostic accuracy of non-invasive SARS-CoV-2 screening tests: a national prospective analysis Open
Background Providing non-invasive, accurate and affordable SARS-CoV-2 tests represents a public health priority, to better control viral circulation while protecting healthcare workers. Saliva is a robust alternative to nasopharyngeal (NP)…
View article: How effective is the BNT162b2 mRNA vaccine against SARS-CoV-2 transmission and infection? A national programme analysis in Monaco, July 2021 to September 2022
How effective is the BNT162b2 mRNA vaccine against SARS-CoV-2 transmission and infection? A national programme analysis in Monaco, July 2021 to September 2022 Open
Background We quantified SARS-CoV-2 dynamics in different community settings and the direct and indirect effect of the BNT162b2 mRNA vaccine in Monaco for different variants of concern (VOC). Methods Between July 2021 and September 2022, w…
View article: Community‐level incidence and treatment seeking during febrile illness: Insights from health behaviour surveys in rural Thailand and Laos
Community‐level incidence and treatment seeking during febrile illness: Insights from health behaviour surveys in rural Thailand and Laos Open
Objective Critical gaps remain in understanding community perceptions and treatment‐seeking behaviours in case of fever. This is especially relevant considering global antimicrobial resistance, where fever is assumed to provoke non‐judicio…
View article: The impact of C-reactive protein testing on treatmentseeking behavior and patients’ attitudes toward their care in Myanmar and Thailand
The impact of C-reactive protein testing on treatmentseeking behavior and patients’ attitudes toward their care in Myanmar and Thailand Open
C-reactive protein (CRP) point-of-care testing can reduce antibiotic prescribing in primary care patients with febrile and respiratory illness, yet little is known about its effects on treatment-seeking behavior. If patients go on to sourc…
View article: The Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination and Infection on Neutralizing Antibodies: A Nation-wide Cross-sectional Analysis
The Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination and Infection on Neutralizing Antibodies: A Nation-wide Cross-sectional Analysis Open
Background Neutralising antibodies (nAbs) play a critical role in the protection against severe COVID-19. In the era of vaccine boosters and repeated SARS-CoV-2 outbreaks, identifying individuals at risk represents a public health priority…
View article: Maritime Public Health Cross Border Cooperation: Principality of Monaco and Italian Liguria Health Port Authority Best Practices
Maritime Public Health Cross Border Cooperation: Principality of Monaco and Italian Liguria Health Port Authority Best Practices Open
The French and Italian Riviera are one of the most important areas in the world for yachting and cruise activity. Even though ports and airports of this area make up a single network, they insist on the territory of two different EU countr…
View article: First Detection of the SARS-CoV-2 Omicron BA.5/22B in Monaco
First Detection of the SARS-CoV-2 Omicron BA.5/22B in Monaco Open
The Omicron BA.5/22B variant has been designated as a “variant of concern” by the World Health Organization. We describe, here, the first evidence in Monaco of infection with an Omicron BA.5/22B variant, probably imported from the Republic…
View article: WHO international standard for SARS-CoV-2 antibodies to determine markers of protection
WHO international standard for SARS-CoV-2 antibodies to determine markers of protection Open
Several studies have shown that neutralising antibody level is a good biomarker for the correlate of protection against SARS-CoV-2 infection.1Bergwerk M Gonen T Lustig Y et al.COVID-19 breakthrough infections in vaccinated health care work…
View article: Associations between maternal obesity and infectious morbidity in Zimbabwean infants
Associations between maternal obesity and infectious morbidity in Zimbabwean infants Open
The prevalence of overweight and obesity is increasing among reproductive-age women in sub-Saharan Africa. Whether maternal body mass index (BMI) influences the risk of infant infections in low- and middle-income countries (LMIC) is uncert…
View article: Evaluation of the Panbio Leptospira IgM ELISA among Outpatients Attending Primary Care in Southeast Asia
Evaluation of the Panbio Leptospira IgM ELISA among Outpatients Attending Primary Care in Southeast Asia Open
Despite estimates suggesting Leptospira spp. being endemic in Southeast Asia, evidence remains limited. Diagnostic accuracy evaluations based on Leptospira ELISA mainly rely on hospitalized and severe patients; therefore, studies measuring…
View article: Fever and health-seeking behaviour among migrants living along the Thai-Myanmar border: a mixed-methods study
Fever and health-seeking behaviour among migrants living along the Thai-Myanmar border: a mixed-methods study Open
The decline of malaria in Southeast Asia has complexified how fever is perceived and what actions are taken towards it. Using a mixed-methods design, we investigated the concept of fever and the determinants influencing health-seeking beha…
View article: Point-of-care C-reactive protein testing and antibiotic prescribing
Point-of-care C-reactive protein testing and antibiotic prescribing Open
In our study, published in 2019 in The Lancet Global Health,1Althaus T Greer RC Swe MMM et al.Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar:…
View article: Inter-prescriber variability in the decision to prescribe antibiotics to febrile patients attending primary care in Myanmar
Inter-prescriber variability in the decision to prescribe antibiotics to febrile patients attending primary care in Myanmar Open
Background Most antibiotic prescribing occurs in primary care. Even within the same health facility, there may be differences between prescribers in their tendency to prescribe antibiotics, which may be masked by summary data. We aimed to …
View article: Precarity and clinical determinants of healthcare-seeking behaviour and antibiotic use in rural Laos and Thailand
Precarity and clinical determinants of healthcare-seeking behaviour and antibiotic use in rural Laos and Thailand Open
Background The social determinants of health are a decisive yet persistently understudied area for tackling global health challenges like antimicrobial resistance (AMR). Precarity is one determinant whose importance is increasingly recogni…
View article: Faculty Opinions recommendation of sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country.
Faculty Opinions recommendation of sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country. Open
Background: Few studies of biomarkers as predictors of outcome in infection have been performed in tropical, low-and middle-income countries where the burden of sepsis is highest.We evaluated whether selected biomarkers could predict 28-da…
View article: Prevalence of Group A Streptococcus in Primary Care Patients and the Utility of C-Reactive Protein and Clinical Scores for Its Identification in Thailand
Prevalence of Group A Streptococcus in Primary Care Patients and the Utility of C-Reactive Protein and Clinical Scores for Its Identification in Thailand Open
Pharyngitis is usually caused by a viral infection for which antibiotics are often unnecessarily prescribed, adding to the burden of antimicrobial resistance. Identifying who needs antibiotics is challenging; microbiological confirmation a…
View article: Sensitivity of C‐reactive protein for the identification of patients with laboratory‐confirmed bacterial infections in northern Tanzania
Sensitivity of C‐reactive protein for the identification of patients with laboratory‐confirmed bacterial infections in northern Tanzania Open
Objective Identifying febrile patients requiring antibacterial treatment is challenging, particularly in low‐resource settings. In South‐East Asia, C‐reactive protein (CRP) has been demonstrated to be highly sensitive and moderately specif…
View article: Faculty Opinions recommendation of Potential usefulness of C-reactive protein and procalcitonin determination in patients admitted for neurological disorders in rural Democratic Republic of Congo.
Faculty Opinions recommendation of Potential usefulness of C-reactive protein and procalcitonin determination in patients admitted for neurological disorders in rural Democratic Republic of Congo. Open
Read the full review for this Faculty Opinions recommended article: Potential usefulness of C-reactive protein and procalcitonin determination in patients admitted for neurological disorders in rural Democratic Republic of Congo.
View article: Antibiotic knowledge, attitudes and practices: new insights from cross-sectional rural health behaviour surveys in low-income and middle-income South-East Asia
Antibiotic knowledge, attitudes and practices: new insights from cross-sectional rural health behaviour surveys in low-income and middle-income South-East Asia Open
Introduction Low-income and middle-income countries (LMICs) are crucial in the global response to antimicrobial resistance (AMR), but diverse health systems, healthcare practices and cultural conceptions of medicine can complicate global e…
View article: Faculty Opinions recommendation of Scrub typhus point-of-care testing: A systematic review and meta-analysis.
Faculty Opinions recommendation of Scrub typhus point-of-care testing: A systematic review and meta-analysis. Open
BackgroundDiagnosing scrub typhus clinically is difficult, hence laboratory tests play a very important role in diagnosis.As performing sophisticated laboratory tests in resource-limited settings is not feasible, accurate point-of-care tes…