Thomas Beikler
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View article: Utilization of dental services of older persons after onset of home care – an observational study from the InSEMaP research project based on German insurance claims data
Utilization of dental services of older persons after onset of home care – an observational study from the InSEMaP research project based on German insurance claims data Open
Background Maintaining a good oral health is important for general health, nutrition, and quality of life. Nevertheless, the utilization of dental services decreases with age. Persons in need of home care, in particular, might face difficu…
View article: Influence of Vitamin D Level on Oral Health Status in Adult Hypophosphatasia
Influence of Vitamin D Level on Oral Health Status in Adult Hypophosphatasia Open
Aim Vitamin D deficiency is common in hypophosphatasia (HPP) patients. However, its impact on oral health is unclear. Therefore, the purpose of this study was to investigate the relationship between Vitamin D levels and oral health in adul…
View article: Effect of Mouth Rinsing and Antiseptic Solutions on Periodontitis Bacteria in an In Vitro Oral Human Biofilm Model
Effect of Mouth Rinsing and Antiseptic Solutions on Periodontitis Bacteria in an In Vitro Oral Human Biofilm Model Open
Background/Objectives: The formation of oral biofilms in periodontal pockets and around dental implants with induction of periodontitis or peri-implantitis is an increasing problem in dental health. The intelligent design of a biofilm make…
View article: Oral microbiome profiles relate periodontal disease and brain health - the PAROMIND Study
Oral microbiome profiles relate periodontal disease and brain health - the PAROMIND Study Open
The relationship between oral microbiome composition and brain health in the general population remains poorly understood. In this study, we inferred a microbiome similarity network based on 16S rRNA sequencing data of crevicular fluid col…
View article: How does overweight affect bone mineral density and oral health in adult hypophosphatasia?– A single center experience
How does overweight affect bone mineral density and oral health in adult hypophosphatasia?– A single center experience Open
Aim The aim of this study was to investigate the influence of overweight (BMI ≥ 25 (kg/m²)) on the oral health status in patients with adult hypophosphatasia (HPP). Materials and methods Throughout a retrospective assessment both oral heal…
View article: Oral microbiome profiles relate periodontal disease and brain health - the PAROMIND Study
Oral microbiome profiles relate periodontal disease and brain health - the PAROMIND Study Open
The relationship between oral microbiome composition and brain he alth in the general population remains poorly understood. In this study, we inferred a microbiome similarity network based on 16S rRNA sequencing data of crevicular fluid co…
View article: Oral health literacy and oral health status of a german adult population with migration background – findings from the MuMi Study
Oral health literacy and oral health status of a german adult population with migration background – findings from the MuMi Study Open
Oral health literacy has been found to be a strong predictor for an individual's oral health outcome. Improving the oral health literacy of patients may help in the efforts to improve oral health behaviors and the overall treatment outcome…
View article: Role of PLP-Level as a predictive marker for oral health status in adult hypophosphatasia
Role of PLP-Level as a predictive marker for oral health status in adult hypophosphatasia Open
Aim The aim of this study was to investigate the role of pyridoxal-5-phosphate (PLP) level on the oral health status as a predictive marker in patients with hypophosphatasia (HPP). Materials and methods Throughout a systematic retrospectiv…
View article: High incidence of periodontitis in patients with ascitic decompensated cirrhosis
High incidence of periodontitis in patients with ascitic decompensated cirrhosis Open
BACKGROUND Periodontitis has been associated with various liver diseases. However, the relevance of periodontitis in the progression of decompensated cirrhosis remains inconclusive. In particular, it is unclear whether the common periodont…
View article: Effect of tetracycline hydrochloride application on dental pulp stem cell metabolism–booster or obstacle for tissue engineering?
Effect of tetracycline hydrochloride application on dental pulp stem cell metabolism–booster or obstacle for tissue engineering? Open
Introduction: Stem cells and scaffolds are an important foundation and starting point for tissue engineering. Human dental pulp stem cells (DPSC) are mesenchymal stem cells with self-renewal and multi-directional differentiation potential,…
View article: Association between periodontitis and depression severity – A cross-sectional study of the older population in Hamburg
Association between periodontitis and depression severity – A cross-sectional study of the older population in Hamburg Open
The aim of the current study is to investigate the association between periodontitis (exposure variable) and depression severity (outcome variable) in an older German population. We evaluated data from 6,209 participants (median age 62 yea…
View article: Association between an Anti-Inflammatory Dietary Score and Periodontitis—Evidence from the Population-Based Hamburg City Health Study
Association between an Anti-Inflammatory Dietary Score and Periodontitis—Evidence from the Population-Based Hamburg City Health Study Open
While the effects of dietary patterns on cardiovascular risk and diabetes have been well studied, the evidence is scarce as to which diet has the greatest anti-inflammatory potential and how dietary patterns are associated with periodontit…
View article: Association between periodontal disease and microstructural brain alterations in the Hamburg City Health Study
Association between periodontal disease and microstructural brain alterations in the Hamburg City Health Study Open
Aim The aim of the PAROBRAIN study was to examine the association of periodontal health with microstructural white matter integrity and cerebral small vessel disease (CSVD) in the Hamburg City Health Study, a large population‐based cohort …
View article: Coffee consumption and associations with blood pressure, LDL-cholesterol and echocardiographic measures in the general population
Coffee consumption and associations with blood pressure, LDL-cholesterol and echocardiographic measures in the general population Open
Coffee, next to water the most widespread beverage, is attributed both harmful and protective characteristics concerning cardiovascular health. This study aimed to evaluate associations of coffee consumption with cardiac biomarkers, echoca…
View article: Interaction of Systemic Morbidity and Oral Health in Ambulatory Patients in Need of Home Care (InSEMaP): an observational study at the sector boundary between dental and general practice care in Germany
Interaction of Systemic Morbidity and Oral Health in Ambulatory Patients in Need of Home Care (InSEMaP): an observational study at the sector boundary between dental and general practice care in Germany Open
Introduction Older people in need of home care are at risk of declining oral health as their visits to dentists are becoming less frequent due to restricted mobility. There is increasing evidence that poor oral health and systemic diseases…
View article: Association between Coffee Consumption and Brain MRI Parameters in the Hamburg City Health Study
Association between Coffee Consumption and Brain MRI Parameters in the Hamburg City Health Study Open
Despite associations of regular coffee consumption with fewer neurodegenerative disorders, its association with microstructural brain alterations is unclear. To address this, we examined the association of coffee consumption with brain MRI…
View article: High prevalence of periodontal disease in patients with NASH- possible association of poor dental health with NASH severity
High prevalence of periodontal disease in patients with NASH- possible association of poor dental health with NASH severity Open
The present study suggests that NASH might be associated with periodontitis, irrespective of the intraoral presence of P.g. and A.a. Moreover, regular dental care utilization might mitigate the course of NASH, and patients should be remind…
View article: Periodontitis is associated with combined handgrip strength but not with skeletal muscle mass index in middle-aged U.S. adults from NHANES 2013-2014
Periodontitis is associated with combined handgrip strength but not with skeletal muscle mass index in middle-aged U.S. adults from NHANES 2013-2014 Open
Objectives: Indicators of oral and periodontal diseases have previously been associated with handgrip strength and muscle mass and function in older adults in several populations. However, research in middle-aged adults on the relationship…
View article: Cultivation of Cryopreserved Human Dental Pulp Stem Cells—A New Approach to Maintaining Dental Pulp Tissue
Cultivation of Cryopreserved Human Dental Pulp Stem Cells—A New Approach to Maintaining Dental Pulp Tissue Open
Human dental pulp stem cells (hDPSCs) are multipotent mesenchymal stem cells (MSCs) that are capable of self-renewal with multilineage differentiation potential. After being cryopreserved, hDPSCs were reported to maintain a high level of p…
View article: Association between periodontitis and heart failure in the general population
Association between periodontitis and heart failure in the general population Open
Aims Data on the association between periodontitis and preclinical cardiac alterations remain scarce. The aim of the current study is to determine if periodontitis is associated with morphological and functional cardiac changes measured by…
View article: Tissue Adhesives in Reconstructive and Aesthetic Surgery—Application of Silk Fibroin-Based Biomaterials
Tissue Adhesives in Reconstructive and Aesthetic Surgery—Application of Silk Fibroin-Based Biomaterials Open
Tissue adhesives have been successfully used in various kind of surgeries such as oral and maxillofacial surgery for some time. They serve as a substitute for suturing of tissues and shorten treatment time. Besides synthetic-based adhesive…
View article: Cross‐sectional analysis of the association of periodontitis with carotid intima media thickness and atherosclerotic plaque in the Hamburg City health study
Cross‐sectional analysis of the association of periodontitis with carotid intima media thickness and atherosclerotic plaque in the Hamburg City health study Open
Background Previous epidemiological studies regarding the association between chronic periodontitis (CP) and carotid intima‐media thickness (cIMT) and subclinical atherosclerosis have been inconclusive. Objective The aim of this study was …
View article: Microbiological and Clinical Effects of a Proanthocyanidin-enriched Extract from Rumex acetosa in Periodontally Healthy Carriers of Porphyromonas gingivalis: a Randomized Controlled Pilot Study
Microbiological and Clinical Effects of a Proanthocyanidin-enriched Extract from Rumex acetosa in Periodontally Healthy Carriers of Porphyromonas gingivalis: a Randomized Controlled Pilot Study Open
Rumex acetosa significantly inhibits the adhesion of Porphyromonas gingivalis (P. g.) to eukaryotic host cells in vitro. The objective of this randomized placebo-controlled pilot-trial was to analyze effects of a mouth rinse containing 0.8…
View article: Periodontitis, dental plaque, and atrial fibrillation in the Hamburg City Health Study
Periodontitis, dental plaque, and atrial fibrillation in the Hamburg City Health Study Open
Background/Aim Atrial fibrillation (AF) is a major health problem and causes heart failure and stroke. Pathophysiological mechanisms indicate a link with oral health including periodontitis (PD), but supporting data are scarce. The aim was…
View article: Association between Dietary Pattern and Periodontitis—A Cross-Sectional Study
Association between Dietary Pattern and Periodontitis—A Cross-Sectional Study Open
The aim of the study was to investigate the relationship between specific known dietary patterns and the prevalence of periodontal disease in a northern population-based cohort study. We evaluated data from 6209 participants of the Hamburg…