Thomas Biniasch
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View article: Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor
Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor Open
The autotaxin-lysophosphatidic acid (ATX-LPA) signaling pathway plays a role in a variety of autoimmune diseases, such as rheumatoid arthritis or neurodegeneration. A link to the pathogenesis of glaucoma is suggested by an overactive ATX-L…