Thomas Bordenave
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View article: Novel Matrix Metalloproteinase 12 Selective Radiotracers for Vascular Molecular Imaging
Novel Matrix Metalloproteinase 12 Selective Radiotracers for Vascular Molecular Imaging Open
Matrix metalloproteinase-12 (MMP-12) is highly upregulated in several inflammatory diseases, including abdominal aortic aneurysm (AAA). Here we report four novel 99mTc-labeled radiotracers derived from a highly selective competitive MMP-12…
View article: Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes
Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes Open
In designing new tracers consisting of a small peptide conjugated to a reporter of comparable size, particular attention needs to be paid to the selection of the reporter group, which can dictate both the in vitro and the in vivo performan…