Thomas Brack
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View article: Are Predictors for Overall Mortality in COPD Patients Robust over Time?
Are Predictors for Overall Mortality in COPD Patients Robust over Time? Open
(1) Background: Mortality is a major outcome in research on chronic obstructive pulmonary disease (COPD) with various predictors described. However, the dynamic courses of important predictors over time are disregarded. This study evaluate…
View article: Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers
Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers Open
Background and Objective: Whether immunological biomarkers combined with clinical characteristics measured during an exacerbation-free period are predictive of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) frequency …
View article: Telehealth mitigates COPD disease progression compared to standard of care: a randomized controlled crossover trial
Telehealth mitigates COPD disease progression compared to standard of care: a randomized controlled crossover trial Open
Background We showed excellent adherence and satisfaction with our telehealth care (TC) approach for COPD. Here, the results of a consecutive randomized controlled trial are presented. Methods Patients were randomly assigned to TC or stand…
View article: Supplementary Material for: Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers
Supplementary Material for: Prediction of Acute COPD Exacerbation in the Swiss Multicenter COPD Cohort Study (TOPDOCS) by Clinical Parameters, Medication Use, and Immunological Biomarkers Open
Background and Objective: Whether immunological biomarkers combined with clinical characteristics measured during an exacerbation-free period are predictive of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) frequency …
View article: Compliance of pharmacotherapy with GOLD-guidelines: a longitudinal study in patients with COPD
Compliance of pharmacotherapy with GOLD-guidelines: a longitudinal study in patients with COPD Open
Fabian A Grewe,1 Noriane A Sievi,1 Matteo Bradicich,1 Maurice Roeder,1 Thomas Brack,2 Martin H Brutsche,3 Martin Frey,4 Sarosh Irani,5 Jörg D Leuppi,6 Robert Thurnheer,7 Christian F Clarenbach,1 Malcolm Kohler1,8 1Pulmonary Division, Unive…
View article: <p>Compliance of Pharmacotherapy with GOLD Guidelines: A Longitudinal Study in Patients with COPD</p>
Compliance of Pharmacotherapy with GOLD Guidelines: A Longitudinal Study in Patients with COPD Open
The compliance of COPD-pharmacotherapy with GOLD-guidelines is suboptimal, especially in lower risk groups. The high rates of missed out treatment-adjustments suggest that the familiarity of physicians with guidelines leaves room for impro…
View article: No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation
No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation Open
Noriane A Sievi,1 Malcolm Kohler,1 Robert Thurnheer,2 Joerg D Leuppi,3 Sarosh Irani,4 Martin Frey,5 Martin Brutsche,6 Thomas Brack,7 Christian F Clarenbach1 1Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland; 2Pulmonar…
View article: <p>No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation</p>
No impact of exacerbation frequency and severity on the physical activity decline in COPD: a long-term observation Open
www.ClinicalTrials.gov, NCT01527773.
View article: Risk of Sleepiness-Related Accidents in Switzerland: Results of an Online Sleep Apnea Risk Questionnaire and Awareness Campaigns
Risk of Sleepiness-Related Accidents in Switzerland: Results of an Online Sleep Apnea Risk Questionnaire and Awareness Campaigns Open
The OSAS awareness campaign of the Swiss Lung League reached a large number of people of both genders and of a wide age range. Many participants suffered from excessive sleepiness and symptoms of sleep apnea were highly prevalent. The camp…
View article: Accelerometer- versus questionnaire-based assessment of physical activity and their changes over time in patients with COPD
Accelerometer- versus questionnaire-based assessment of physical activity and their changes over time in patients with COPD Open
Evaluation of objectively measured and self-reported PA and their annual changes revealed no agreement in patients with COPD. Therefore, the evaluated questionnaire seems not helpful for measurement of PA and its changes over time.
View article: Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep
Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep Open
The complexity of central breathing disturbances during sleep has become increasingly obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic breathing with apnoeas, or irregular breathing in patients with cardiovasc…