Thomas Chaly
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View article: Early patient and liver allograft outcomes from donation after circulatory death donors using thoracoabdominal normothermic regional: a multi-center observational experience
Early patient and liver allograft outcomes from donation after circulatory death donors using thoracoabdominal normothermic regional: a multi-center observational experience Open
Background Donation after circulatory death (DCD) liver allografts are associated with higher rates of primary non-function (PNF) and ischemic cholangiopathy (IC). Advanced recovery techniques, including thoracoabdominal normothermic regio…
View article: Radiosynthesis and in vivo imaging of [11C]BTFP, a potent inhibitor of VEGFR2
Radiosynthesis and in vivo imaging of [11C]BTFP, a potent inhibitor of VEGFR2 Open
Altered expression of VEGFR2 is reported in the pathology of neurological, neuropsychiatric, brain malignancies and developmental disorders. PET imaging that allows for in vivo visualization of specific targets on the molecular level allow…
View article: Kidney Discard Rates in the United States During American Transplant Congress Meetings
Kidney Discard Rates in the United States During American Transplant Congress Meetings Open
Background Deceased-donor kidney discard rates vary by region, but it is unknown whether discard rates and transplant outcomes vary during the American Transplant Congress (ATC) each year. Methods Using national registry data, we determine…
View article: Mucocele mimicking a gallbladder in a transplanted liver: A case report and review of the literature
Mucocele mimicking a gallbladder in a transplanted liver: A case report and review of the literature Open
Biliary mucoceles after deceased donor liver transplantation are a rarity, and mucoceles mimicking a gallbladder from the recipient remnant cystic duct have not been described until this case. We describe a 48-year-old male who presented w…
View article: Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia
Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia Open
Chronic levodopa treatment leads to the appearance of dyskinesia in the majority of Parkinson’s disease patients. Neurovascular dysregulation in putaminal and pallidal regions is thought to be an underlying feature of this complication of …
View article: Fluorine-18-fluorodihydroxyphenylalanine Positron-emission Tomography Scans of Neuroendocrine Tumors (Carcinoids and Pheochromocytomas)
Fluorine-18-fluorodihydroxyphenylalanine Positron-emission Tomography Scans of Neuroendocrine Tumors (Carcinoids and Pheochromocytomas) Open
Objectives: Conventional methods of imaging neuroendocrine tumors with computed tomography, magnetic resonance imaging, indium-111-octreotide, or radiolabeled metaiodobenzilguanidine scintigraphy have limitations. This pilot study tried to…
View article: Early Results of Pilot Study Using Hepatitis C Virus (HCV) Positive Kidneys to Transplant HCV Infected Patients with End-Stage Renal Disease Allowing for Successful Interferon-Free Direct Acting Antiviral Therapy after Transplantation
Early Results of Pilot Study Using Hepatitis C Virus (HCV) Positive Kidneys to Transplant HCV Infected Patients with End-Stage Renal Disease Allowing for Successful Interferon-Free Direct Acting Antiviral Therapy after Transplantation Open
HCV-positive patients with ESRD can successfully receive an HCV-positive donor's kidney. Once transplanted, these patients can receive DAA therapy and achieve SVR. Use of HCV-positive organs reduced time on the waitlist by greater than thr…
View article: Human Radiation Dosimetry for the <i>N</i>-Methyl-d-Aspartate Receptor Radioligand <sup>11</sup>C-CNS5161
Human Radiation Dosimetry for the <i>N</i>-Methyl-d-Aspartate Receptor Radioligand <sup>11</sup>C-CNS5161 Open
The radiation dosimetry for (11)C-CNS5161 for a standard single injection of 555 MBq (15 mCi) will result in an effective dose equivalent of 5.9 mSv (0.59 rem) and a lung dose of 21.8 mGy (2.18 rad) in young, healthy subjects.