Explanipedia

The Future of the Psychiatrist Open

James B. Potash, Alex McClanahan, J. A. Davidson, William E. Butler, Nathan Carroll , et al. · 2025

Objective The American Psychiatric Association (APA) issued a 2023 report on the future of psychiatry, focusing on how the organization should position itself in relation to coming developments over the next 10 years. Here, we follow up wi…

Charophytes (Charophyceae, Charales) of South Kazakhstan: Diversity, Distribution, and Tentative Red List Open

Satbay Nurashov, Gaukhar Jumakhanova, Sophia Barınova, Роман Романов, Elmira Sametova , et al. · 2023

The presented research was conducted during 2019–2022 in south and southeast Kazakhstan to document the species richness, distribution, and ecology of charophytes (Characeae) as a first step towards to estimate the need for species protect…

Host-microbiome metabolism of a plant toxin in bees Open

Erick V. S. Motta, Alejandra Gage, Thomas E. Smith, Kristin J. Blake, Waldan K. Kwong , et al. · 2022

While foraging for nectar and pollen, bees are exposed to a myriad of xenobiotics, including plant metabolites, which may exert a wide range of effects on their health. Although the bee genome encodes enzymes that help in the metabolism of…

Author response: Host-microbiome metabolism of a plant toxin in bees Open

Erick V. S. Motta, Alejandra Gage, Thomas E. Smith, Kristin J. Blake, Waldan K. Kwong , et al. · 2022

Article Figures and data Abstract Editor's evaluation eLife digest Introduction Results Discussion Methods Data availability References Decision letter Author response Article and author information Metrics Abstract While foraging for nect…

Cooperative host-microbe metabolism of a plant toxin in bees Open

Erick V. S. Motta, Alejandra Gage, Thomas E. Smith, Kristin J. Blake, Waldan K. Kwong , et al. · 2022

During pollination, bees are exposed to a myriad of xenobiotics, including plant metabolites, which may exert a wide range of effects on their health. Although bees encode enzymes that help in the metabolism of xenobiotics, they still have…

Microalgae Indicators of Charophyte Habitats of South and Southeast Kazakhstan Open

Elmira Sametova, Gaukhar Jumakhanova, Satbay Nurashov, Sophia Barınova, Aibek Jiyenbekov , et al. · 2022

Charophyte algae is a very sensitive group of organisms occupying Kazakhstan waterbodies. They are distributed throughout the country; however, not enough studies have been conducted, especially in the southern region. Research carried out…

Table of Contents Open

Warren Heston, Neil H. Bander, Connie Lippowitsch, Adaeze A. Emeka, William J. Catàlona , et al. · 2022

Elucidation of host and symbiont contributions to peptidoglycan metabolism based on comparative genomics of eight aphid subfamilies and their Buchnera Open

Thomas E. Smith, Yiyuan Li, Julie Perreau, Nancy A. Moran · 2022

Pea aphids ( Acyrthosiphon pisum ) are insects containing genes of bacterial origin with putative functions in peptidoglycan (PGN) metabolism. Of these, rlpA1-5 , amiD , and ldcA are highly expressed in bacteriocytes, specialized aphid cel…

Flora of Algae and Cyanobacteria of Continental Waters of Israel in the XXI Century: Taxonomy, Autecology and Water Quality Indicators Open

Sophia Barınova, Thomas E. Smith · 2022

The article presents a list of algal species and cyanobacteria found in the continental waters of Israel in 1898–2022. Research progressed in 2000–2022 by increasing the list from 1261 to 1628 species belonging to fourteen phyla. Taxonomic…

Microalgae, in Spatial Assessment of the Drainage Basin, Influences on the Ecosystem of Lake Agmon, Israel Open

Sophia Barınova, Thomas E. Smith, П. М. Царенко · 2022

Based on the collected data on the diversity of microalgae and environmental indicators in dry and wet seasons during 2011–2018, from 45 samples, 59 species of microalgae were identified in the ornithological object—Lake Agmon in the Hula …

Pulse Dosing of 10-kHz Paresthesia-Independent Spinal Cord Stimulation Provides the Same Efficacy with Substantial Reduction of Device Recharge Time Open

David Provenzano, Jordan Tate, Mayank Gupta, Cong Yu, Paul Verrills , et al. · 2021

Objective This study was designed to assess whether using pulse dosing (PD) (regularly cycled intermittent stimulation) of high-frequency 10-kHz spinal cord stimulation (10-kHz SCS) can reduce device recharge time while maintaining efficac…

Comparative genomics of eight aphid subfamilies reveals variable relationships between host horizontally-transferred genes and symbiont peptidoglycan metabolism. Open

Thomas E. Smith, Yiyuan Li, Nancy A. Moran · 2021

Genome assemblies, annotations, and orthologs of aphids (Geopemphigus sp., Stegophylla sp., Chaitophorus viminalis, and Pemphigus obesinymphae) and their symbionts. step1_final_assemblies_and_annotations…

Comparative genomics of eight aphid subfamilies reveals variable relationships between host horizontally-transferred genes and symbiont peptidoglycan metabolism. Open

Thomas E. Smith, Yiyuan Li, Nancy A. Moran · 2021

Genome assemblies, annotations, and orthologs of aphids (Geopemphigus sp., Stegophylla sp., Chaitophorus viminalis, and Pemphigus obesinymphae) and their symbionts. step1_final_assemblies_and_annotation…

Comparative genomics of eight aphid subfamilies reveals variable relationships between host horizontally-transferred genes and symbiont peptidoglycan metabolism. Open

Thomas E. Smith, Yiyuan Li, Nancy A. Moran · 2021

Genome assemblies, annotations, and orthologs of aphids (Geopemphigus sp., Stegophylla sp., Chaitophorus viminalis, and Pemphigus obesinymphae) and their symbionts. step1_final_assemblies_and_annotation…

Comparative genomics of eight aphid subfamilies reveals variable relationships between host horizontally-transferred genes and symbiont peptidoglycan metabolism. Open

Thomas E. Smith, Yiyuan Li, Nancy A. Moran · 2021

Genome assemblies, annotations, and orthologs of aphids (Geopemphigus sp., Stegophylla sp., Chaitophorus viminalis, and Pemphigus obesinymphae) and their symbionts. step1_final_assemblies_and_annotation…

Multi-fidelity Machine Learning. Open

John Jakeman, Michael Eldred, Gianluca Geraci, Teresa Portone, Ahmad Rushdi , et al. · 2021

Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers Open

Nader N. El-Chaar, Thomas E. Smith, Gajendra Shrestha, Stephen Piccolo, Mary Kay Harper , et al. · 2021

Patients diagnosed with basal-like breast cancer suffer from poor prognosis and limited treatment options. There is an urgent need to identify new targets that can benefit patients with basal-like and claudin-low (BL-CL) breast cancers. We…

Topsentinol L Trisulfate, a new Marine Natural Product, that Targets Basal-like and Claudin-low Breast Cancers Open

Nader N. El-Chaar, Thomas E. Smith, Gajendra Shrestha, Stephen Piccolo, Mary Kay Harper , et al. · 2020

Background Breast cancer is a heterogeneous disease. Genomic studies have revealed five different intrinsic subtypes - Luminal A, Luminal B, HER2-enriched, Claudin-low, and Basal-like. Patients diagnosed with Basal-like or Claudin-low brea…

Coordination of host and symbiont gene expression reveals a metabolic tug-of-war between aphids and <i>Buchnera</i> Open

Thomas E. Smith, Nancy A. Moran · 2020

Symbioses between animals and microbes are often described as mutualistic, but are subject to tradeoffs that may manifest as shifts in host and symbiont metabolism, cellular processes, or symbiont density. In pea aphids, the bacterial symb…

Algae Diversity and Ecology during a Summer Assessment of Water Quality in the Abraham Lincoln Birthplace National Historical Park, USA Open

Sophia Barınova, Thomas E. Smith · 2019

There were 88 species of algae and cyanobacteria observed from seven sites in the Abraham Lincoln Birthplace National Historical Park (Hodgenville, Kentucky, USA). This was the first algal investigation study in the park. There were 21 sam…

Gene Family Evolution in the Pea Aphid Based on Chromosome-Level Genome Assembly Open

Yiyuan Li, Hyun-Jin Park, Thomas E. Smith, Nancy A. Moran · 2019

Genome structural variations, including duplications, deletions, insertions, and inversions, are central in the evolution of eukaryotic genomes. However, structural variations present challenges for high-quality genome assembly, hampering …

A Preliminary Report on Aerophytic Cyanoprokaryota and Chlorophyta from Rocky Mountain National Park and Fraser Experimental Forest, Colorado, USA Open

Thomas E. Smith, Steven L. Stephenson · 2018

This paper reports the results of a study of the aerophytic algae from Fraser Research Forest (Fraser, Colorado) and the Loch Vale site in Rocky Mountain National Park, Colorado. Ten bark samples from two trees (Engelmann spruce and Dougla…

A Preliminary Report on the Aerophytic Cyanoprokaryota and Algae from the Great Smoky Mountains National Park, USA Open

Thomas E. Smith, Adam W. Rollins, Steven L. Stephenson · 2018

An annotated list is provided for 38 species of aerophytic algae (31 cyanobacteria, six Chlorophyta, and one Bacillariophyta) that were recovered from eight soil study sites (in coniferous and hardwood forests) collected during surveys car…

Chemical Metagenomics of an Anti-HIV Compound From Uncultivated Symbionts Open

Thomas E. Smith, Christopher D. Pond, Elizabeth Pierce, Zachary P. Harmer, Jason C. Kwan , et al. · 2018

Accessing chemical diversity from the uncultivated symbionts of small marine animals Open

Thomas E. Smith, Christopher D. Pond, Elizabeth Pierce, Zachary P. Harmer, Jason C. Kwan , et al. · 2018

The City of New York: In the Year of Washington's Inauguration, 1789 Open

Thomas E. Smith · 2017

Book digitized by Google from the library of the New York Public Library and uploaded to the Internet Archive by user tpb.

Biogenetic Relationships of Bioactive Sponge Merotriterpenoids Open

Thomas E. Smith · 2017

Hydroquinone meroterpenoids, especially those derived from marine sponges, display a wide range of biological activities. However, use of these compounds is limited by their inaccessibility; there is no sustainable supply of these compound…

Long-Term Improvements in Chronic Axial Low Back Pain Patients Without Previous Spinal Surgery: A Cohort Analysis of 10-kHz High-Frequency Spinal Cord Stimulation over 36 Months Open

Adnan Al‐Kaisy, Stefano Palmisani, Thomas E. Smith, Roy Carganillo, Russell Houghton , et al. · 2017

These results suggest that 10-kHz high-frequency SCS may provide significant, long-term back pain relief, improvement in disability and quality of life, and reduction in opioids for nonsurgical refractory back pain.

Influenza Research Database: An integrated bioinformatics resource for influenza virus research Open

Yun Zhang, Brian D. Aevermann, Tavis K. Anderson, David F. Burke, Gwenae͏̈lle Dauphin , et al. · 2016

The Influenza Research Database (IRD) is a U.S. National Institute of Allergy and Infectious Diseases (NIAID)-sponsored Bioinformatics Resource Center dedicated to providing bioinformatics support for influenza virus research. IRD facilita…

Safety and efficacy of cervical 10 kHz spinal cord stimulation in chronic refractory primary headaches: a retrospective case series Open

Giorgio Lambru, Michele Trimboli, Stefano Palmisani, Thomas E. Smith, Adnan Al‐Kaisy · 2016

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