Thomas F. Allison
YOU?
Author Swipe
View article: Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease
Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease Open
View article: Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis
Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis Open
View article: Data from: Identification of neural oscillations and epileptiform changes in human brain organoids.
Data from: Identification of neural oscillations and epileptiform changes in human brain organoids. Open
Seurat object containing processed single-cell RNA sequencing data described in: Samarasinghe, R.A., Miranda, O.A., Buth, J.E. et al. Identification of neural oscillations and epileptiform changes in human brain organoids. Nat…
View article: Identification of neural oscillations and epileptiform changes in human brain organoids
Identification of neural oscillations and epileptiform changes in human brain organoids Open
View article: Data from: Identification of neural oscillations and epileptiform changes in human brain organoids.
Data from: Identification of neural oscillations and epileptiform changes in human brain organoids. Open
Seurat object containing processed single-cell RNA sequencing data described in: Samarasinghe, R.A., Miranda, O.A., Buth, J.E. et al. Identification of neural oscillations and epileptiform changes in human brain organoids. Nat…
View article: Single-soma transcriptomics of tangle-bearing neurons in Alzheimer’s disease reveals the signatures of tau-associated synaptic dysfunction
Single-soma transcriptomics of tangle-bearing neurons in Alzheimer’s disease reveals the signatures of tau-associated synaptic dysfunction Open
Aggregation of hyperphosphorylated tau in neurofibrillary tangles (NFTs) is closely associated with neuronal death and cognitive decline in Alzheimer’s disease (AD). To define the signatures that distinguish between aggregation-prone and r…
View article: Defining Transcriptional Signatures of Human Hair Follicle Cell States
Defining Transcriptional Signatures of Human Hair Follicle Cell States Open
View article: Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells
Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells Open
View article: Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells Open
View article: Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells
Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells Open
Genetic changes in human pluripotent stem cells (hPSCs) gained during culture can confound experimental results and potentially jeopardize the outcome of clinical therapies. Particularly common changes in hPSCs are trisomies of chromosomes…
View article: Evidence for bystander signalling between human trophoblast cells and human embryonic stem cells
Evidence for bystander signalling between human trophoblast cells and human embryonic stem cells Open
View article: Delineating the mechanisms behind fate decisions of human embryonic stem cells
Delineating the mechanisms behind fate decisions of human embryonic stem cells Open
Human embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos. Once explanted and cultured in vitro under appropriate conditions, human ES cells retain pluripotency (i.e. capacity to differentiate into al…
View article: Human pluripotent stem cells as tools for high-throughput and high-content screening in drug discovery
Human pluripotent stem cells as tools for high-throughput and high-content screening in drug discovery Open
A significant bottleneck in drug discovery is the lack of suitable models for sensitive, reliable, and rapid assessment of lead molecules in preclinical stages of drug discovery. Human pluripotent stem cells (hPSCs) derived either from ear…