Thomas F. Rice
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View article: Natural killer cells and innate lymphoid cells but not NKT cells are mature in their cytokine production at birth
Natural killer cells and innate lymphoid cells but not NKT cells are mature in their cytokine production at birth Open
Early life is a time of increased susceptibility to infectious diseases and development of allergy. Innate lymphocytes are crucial components of the initiation and regulation of immune responses at mucosal surfaces, but functional differen…
View article: Update on Transplacental Transfer of IgG Subclasses: Impact of Maternal and Fetal Factors
Update on Transplacental Transfer of IgG Subclasses: Impact of Maternal and Fetal Factors Open
Transplacental antibody transfer from mother to fetus provides protection from infection in the first weeks of life, and the four different subclasses of IgG (IgG1, IgG2, IgG3, and IgG4) have diverse roles in protection against infection. …
View article: Antibody glycosylation in pregnancy and in newborns: biological roles and implications
Antibody glycosylation in pregnancy and in newborns: biological roles and implications Open
Purpose of review Glycosylation patterns have the potential to affect the function of antibody, antibody half-life and transplacental transfer from mother to foetus. Here, we review recent advances in our understanding of how glycosylation…
View article: Maternal and infant immune responses to pertussis vaccination in pregnancy
Maternal and infant immune responses to pertussis vaccination in pregnancy Open
Background: In the United Kingdom in 2012, there was a pertussis epidemic that disproportionately affected infants too young to be protected by immunisation. In an attempt to protect this vulnerable age group, pertussis vaccination was int…
View article: Antibody responses to <i>Bordetella pertussis</i> and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy – a prospective, observational cohort study from the United Kingdom
Antibody responses to <i>Bordetella pertussis</i> and other childhood vaccines in infants born to mothers who received pertussis vaccine in pregnancy – a prospective, observational cohort study from the United Kingdom Open
Summary The maternal Tdap (tetanus, diphtheria and acellular pertussis) vaccination programme in the United Kingdom has successfully reduced cases of pertussis in young infants. In addition to prevention of pertussis cases, it is also impo…
View article: The impact of timing of maternal influenza immunization on infant antibody levels at birth
The impact of timing of maternal influenza immunization on infant antibody levels at birth Open
Summary Pregnant women and infants are at an increased risk of severe disease after influenza infection. Maternal immunization is a potent tool to protect both these at-risk groups. While the primary aim of maternal influenza vaccination i…
View article: One size fits all? Antibody avidity measurement against multiple antigens in maternal vaccination studies
One size fits all? Antibody avidity measurement against multiple antigens in maternal vaccination studies Open
This article refers to:Influence of maternal vaccination against diphtheria, tetanus, and pertussis on the avidity of infant antibody responses to a pertussis containing vaccine in Belgium