Thomas Fellmeth
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BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains Open
The Bcl-2 family controls apoptosis by direct interactions of pro- and anti-apoptotic proteins. The principle mechanism is binding of the BH3 domain of pro-apoptotic proteins to the hydrophobic groove of anti-apoptotic siblings, which is t…
BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains Open
The Bcl-2 family controls apoptosis by direct interactions of pro- and anti-apoptotic proteins. The principle mechanism is binding of the BH3 domain of pro-apoptotic proteins to the hydrophobic groove of anti-apoptotic siblings, which is t…
View article: CCDC 2189955: Experimental Crystal Structure Determination
CCDC 2189955: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Chasing Polycyclic Natural Products: 5/6/5‐ or 5/6/6‐Carbotricyclic Scaffold Construction <i>via</i> Stereodivergent Diels‐Alder Reaction of Chiral Hydrindanes and Their Boron Complexes
Chasing Polycyclic Natural Products: 5/6/5‐ or 5/6/6‐Carbotricyclic Scaffold Construction <i>via</i> Stereodivergent Diels‐Alder Reaction of Chiral Hydrindanes and Their Boron Complexes Open
Chiral trans ‐hydrindanes (bicyclo[4.3.0]nonanes) are important building blocks of polycyclic natural products. In order to access 5/6/5‐ and 5/6/6‐carbotricyclic scaffolds scope and limitation of [4+2] cycloadditions of tetrahydroindanone…