Thomas Goeury
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View article: Evidence for Pathogen‐Driven Selection Acting on <i>HLA‐DPB1</i> in Response to <i>Plasmodium falciparum</i> Malaria in West Africa
Evidence for Pathogen‐Driven Selection Acting on <i>HLA‐DPB1</i> in Response to <i>Plasmodium falciparum</i> Malaria in West Africa Open
African populations remain underrepresented in studies of human genetic diversity, despite a growing interest in understanding how they have adapted to the diverse environments they live in. In particular, understanding the genetic basis o…
View article: MADaM, an accurate and fast unsupervised algorithm for genotyping of short sequencing reads
MADaM, an accurate and fast unsupervised algorithm for genotyping of short sequencing reads Open
We present here MADaM (Multiplexed Amplicon Data Miner), an original algorithm designed to de-novo genotyping of small sequencing reads that do not require assembly step. It performs a classification of the reads based on an original set o…
View article: Effect of SARS-CoV-2 prior infection and mRNA vaccination on contagiousness and susceptibility to infection
Effect of SARS-CoV-2 prior infection and mRNA vaccination on contagiousness and susceptibility to infection Open
View article: Contribution à l'étude des facteurs évolutifs déterminant les profils moléculaires des gènes HLA des populations humaines
Contribution à l'étude des facteurs évolutifs déterminant les profils moléculaires des gènes HLA des populations humaines Open
Cette thèse porte sur l'étude des facteurs évolutifs contribuant à la distribution du polymorphisme du complexe des antigènes leucocytaires humains (HLA). Utilisant des données moléculaires HLA issues de séquençages ADN, il vise à apporter…
View article: Current and future distributions of Espeletiinae (Asteraceae) in the Venezuelan Andes based on statistical downscaling of climatic variables and niche modelling
Current and future distributions of Espeletiinae (Asteraceae) in the Venezuelan Andes based on statistical downscaling of climatic variables and niche modelling Open
Background: Páramos are the high-elevation ecosystems of the humid tropical Andes, characterised by the presence of giant rosettes of the Espeletiinae subtribe (Asteraceae). Forecasted climate change is likely to reduce the extent o…
View article: Mandenka from Senegal
Mandenka from Senegal Open
A total of 72 unrelated Mandenka individuals from Eastern Senegal, Niokholo region, were typed using Next Generation Sequencing (library preparation with the Holotype HLA X2 and MIA FORA NGS HLA Typing kits, sequencing with Illumina MiSeq,…
View article: Deciphering the fine nucleotide diversity of full HLA class I and class II genes in a well‐documented population from sub‐Saharan Africa
Deciphering the fine nucleotide diversity of full HLA class I and class II genes in a well‐documented population from sub‐Saharan Africa Open
With the aim to understand how next‐generation sequencing (NGS) improves both our assessment of genetic variation within populations and our knowledge on HLA molecular evolution, we sequenced and analysed 8 HLA loci in a well‐documented po…