Jacob T. Gutsche
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View article: Quantifying Sleep-Wake Rhythms in the Hospital Environment with Digital Technologies
Quantifying Sleep-Wake Rhythms in the Hospital Environment with Digital Technologies Open
Postoperative clinical care is prone to circadian desynchronization that, in turn, may influence health outcomes. We collected 1.8 million data points using 11 remote sensors during preoperative, in-hospital and post-discharge settings in …
View article: Intracannula Thrombus Formation Associated With Dual Lumen ProtekDuo Cannula in Extracorporeal Membrane Oxygenation (ECMO)
Intracannula Thrombus Formation Associated With Dual Lumen ProtekDuo Cannula in Extracorporeal Membrane Oxygenation (ECMO) Open
Extracorporeal membrane oxygenation (ECMO) is used in cases of severe respiratory failure refractory to medical management. Use of ECMO is increasing, along with new cannulation strategies including oxygenated right ventricular assist devi…
View article: First‐in‐man successful use of the SPECTRUM percutaneous dual‐stage right ventricle and right atrium to pulmonary artery ventricular assist device
First‐in‐man successful use of the SPECTRUM percutaneous dual‐stage right ventricle and right atrium to pulmonary artery ventricular assist device Open
Here we describe the first-in-man successful use of the dual-stage RA and RV to PA Spectrum cannula in a patient with severe COVID acute respiratory distress syndrome and acute right ventricular failure, bridged to recovery.
View article: Reduced survival in patients requiring chest tubes with COVID-19 acute respiratory distress syndrome
Reduced survival in patients requiring chest tubes with COVID-19 acute respiratory distress syndrome Open
Requiring a chest tube in COVID-19 is a negative prognostic end point. Delayed development of chest tube requirement was associated with a decreased survival and could reflect a poor healing phenotype.
View article: ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest.
ReTEECA Trial. Rescue TransEsophageal Echocardiography for In-Hospital Cardiac Arrest. Open
This trial is aimed at studying the utility and interventional outcomes of rescue transesophageal echocardiography (RescueTEE) to aid in diagnosis, change in management, and outcomes during CPR by using a point of care RescueTEE protocol i…
View article: ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part II: Cardiac, surgical, perioperative, operative, and post-operative challenges and management statements
ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part II: Cardiac, surgical, perioperative, operative, and post-operative challenges and management statements Open
Patients with connective tissue disease (CTD) present unique surgical, perioperative, operative, and postoperative challenges related to the often underlying severe pulmonary hypertension and right ventricular dysfunction. The Internationa…
View article: Characteristics, Outcomes, and Trends of Patients With COVID-19–Related Critical Illness at a Learning Health System in the United States
Characteristics, Outcomes, and Trends of Patients With COVID-19–Related Critical Illness at a Learning Health System in the United States Open
Agency for Healthcare Research and Quality.
View article: Low Microcirculatory Perfused Vessel Density and High Heterogeneity are Associated With Increased Intensity and Duration of Lactic Acidosis After Cardiac Surgery with Cardiopulmonary Bypass
Low Microcirculatory Perfused Vessel Density and High Heterogeneity are Associated With Increased Intensity and Duration of Lactic Acidosis After Cardiac Surgery with Cardiopulmonary Bypass Open
Introduction: Lactic acidosis after cardiac surgery with cardiopulmonary bypass is common and associated with an increase in postoperative morbidity and mortality. A number of potential causes for an elevated lactate after cardiopulmonary …
View article: The I-READI Quality and Safety Framework: A Health System’s Response to Airway Complications in Mechanically Ventilated Patients with Covid-19
The I-READI Quality and Safety Framework: A Health System’s Response to Airway Complications in Mechanically Ventilated Patients with Covid-19 Open
A team at the University of Pennsylvania Health System devised the I-READI conceptual framework — for Integration, Root Cause Analysis, Evidence Review, Adaptation, Dissemination, and Implementation — to help health care organizations resp…
View article: Benchmarking Critical Care Well-Being: Before and After the Coronavirus Disease 2019 Pandemic
Benchmarking Critical Care Well-Being: Before and After the Coronavirus Disease 2019 Pandemic Open
Objectives: Examine well-being, measured as burnout and professional fulfillment, across critical care healthcare professionals, ICUs, and hospitals within a health system; examine the impact of the coronavirus disease 2019 pandemic. Desig…
View article: Extracorporeal Membrane Oxygenation During the Coronavirus Disease 2019 Pandemic*
Extracorporeal Membrane Oxygenation During the Coronavirus Disease 2019 Pandemic* Open
In the midst of the 2009 influenza A H1N1 pandemic, clinicians turned to extracorporeal membrane oxygenation (ECMO) as a strategy to save lives (1–3). Based on the H1N1 experience, and the ECMO to Rescue Lung Injury in Severe Acute Respira…