Thomas H. Everett
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View article: Cardiac structural, functional, and energetic assessments during and after pregnancy in women with gestational diabetes mellitus, preeclampsia, and healthy pregnancy
Cardiac structural, functional, and energetic assessments during and after pregnancy in women with gestational diabetes mellitus, preeclampsia, and healthy pregnancy Open
Women with GDM or preeclampsia exhibit similar myocardial phenotypes during pregnancy with persistent subclinical alterations in LV mass, energetics, and GLS 12-months postpartum. These myocardial alterations are similar to those detected …
View article: Assessing Skin Sympathetic Nerve Activity and Cardiac Effects in Patients with Gastric Electrical Stimulation
Assessing Skin Sympathetic Nerve Activity and Cardiac Effects in Patients with Gastric Electrical Stimulation Open
Background:Gastric Electrical Stimulation (GES) is a therapy for gastroparesis patients, alleviating symptoms like nausea, vomiting, and poor gastric emptying. The therapeutic impact of GES is believed to stem from changes in autonomic ner…
View article: Acclimation Protocol to Minimize Stress in Immobilized Rats During Non-Invasive Multimodal Sensing of the Autonomic Nervous System
Acclimation Protocol to Minimize Stress in Immobilized Rats During Non-Invasive Multimodal Sensing of the Autonomic Nervous System Open
Introduction Rodent models are often used in spinal cord injury investigations to measure physiological parameters but require rats to be restrained during data collection to prevent motion and stress-induced artifacts. Materials and Metho…
View article: Time and frequency domain analysis of physiological features during autonomic dysreflexia after spinal cord injury
Time and frequency domain analysis of physiological features during autonomic dysreflexia after spinal cord injury Open
Introduction Autonomic dysreflexia (AD) affects about 70% of individuals with spinal cord injury (SCI) and can have severe consequences, including death if not promptly detected and managed. The current gold standard for AD detection invol…
View article: Non-Invasive Detection of Autonomic Dysreflexia Using AI: Advancements in Spinal Cord Injury Care
Non-Invasive Detection of Autonomic Dysreflexia Using AI: Advancements in Spinal Cord Injury Care Open
The authors have requested that this preprint be removed from Research Square.
View article: 167 Maternal myocardial alterations during pregnancy and their recovery twelve months’ post-partum in women with pregnancies complicated by gestational diabetes or preeclampsia- a single centre, longitudinal cohort study
167 Maternal myocardial alterations during pregnancy and their recovery twelve months’ post-partum in women with pregnancies complicated by gestational diabetes or preeclampsia- a single centre, longitudinal cohort study Open
Background Gestational diabetes mellitus (GDM) and preeclampsia (PE) are the leading obstetric complications of pregnancy. Both are associated with a substantial increase in the risk of long-term cardiovascular disease. However, pregnant w…
View article: Automatic Detection and Characterization of Autonomic Dysreflexia Using Multi-Modal Non-Invasive Sensing and Neural Networks
Automatic Detection and Characterization of Autonomic Dysreflexia Using Multi-Modal Non-Invasive Sensing and Neural Networks Open
Autonomic dysreflexia (AD) frequently occurs in persons with spinal cord injuries (SCIs) above the T6 level triggered by different stimuli below the level of injury. If improperly managed, AD can have severe clinical consequences, even pos…
View article: Maternal cardiac changes in women with obesity and gestational diabetes mellitus
Maternal cardiac changes in women with obesity and gestational diabetes mellitus Open
Background- Gestational diabetes mellitus (GDM) is the most prevalent metabolic disorder during pregnancy and is associated with increased risks of cardiovascular morbidity and mortality in later life. Compromised cardiac energy producti…
View article: Maternal cardiac changes in women with obesity and gestational diabetes mellitus
Maternal cardiac changes in women with obesity and gestational diabetes mellitus Open
Background- Gestational diabetes mellitus (GDM) is the most prevalent metabolic disorder during pregnancy and is associated with increased risks of cardiovascular morbidity and mortality in later life. Compromised cardiac energy producti…
View article: Feature Selection Techniques for a Machine Learning Model to Detect Autonomic Dysreflexia
Feature Selection Techniques for a Machine Learning Model to Detect Autonomic Dysreflexia Open
Feature selection plays a crucial role in the development of machine learning algorithms. Understanding the impact of the features on a model, and their physiological relevance can improve the performance. This is particularly helpful in t…
View article: 137 Gestational diabetes, preeclampsia and the maternal heart
137 Gestational diabetes, preeclampsia and the maternal heart Open
Background Gestational diabetes mellitus (GDM) and preeclampsia (pE) are both associated with an increased risk of cardiovascular mortality and morbidity, including an increased risk of developing heart failure in later life. Both conditio…
View article: Application of Physiological Autonomic Activity Tracking GUI and Computational Algorithms for Measuring Persistent Vagal Nerve Dysfunction After Recovery from SARS‐CoV‐2 Infection
Application of Physiological Autonomic Activity Tracking GUI and Computational Algorithms for Measuring Persistent Vagal Nerve Dysfunction After Recovery from SARS‐CoV‐2 Infection Open
Post‐Acute Sequelae of SARS‐CoV‐2 infection (PASC) is now recognized as a constellation of symptoms such as postural hypotension, anxiety, and “brain fog” in addition to autonomic nervous system dysfunction such as tachycardia and labile h…
View article: Heart Rate Variability Parameters Indicate Altered Autonomic Tone in Patients with COVID‐19
Heart Rate Variability Parameters Indicate Altered Autonomic Tone in Patients with COVID‐19 Open
The COVID‐19 disease induces long term heart health complications and may induce autonomic nervous system dysfunction. Heart Rate Variability (HRV) is a measure of sympathetic (SNS) and parasympathetic (PNS) control of heart function. Rece…
View article: Skin Sympathetic Nerve Activity and the Short-Term QT Interval Variability in Patients With Electrical Storm
Skin Sympathetic Nerve Activity and the Short-Term QT Interval Variability in Patients With Electrical Storm Open
Background : Skin sympathetic nerve activity (SKNA) and QT interval variability are known to be associated with ventricular arrhythmias. However, the relationship between the two remains unclear. Objective : The aim was to test the hypothe…
View article: Subcutaneous nerve stimulation in canine model of persistent atrial fibrillation v1
Subcutaneous nerve stimulation in canine model of persistent atrial fibrillation v1 Open
This animal protocol was approved by the Institutional Animal Care and Use Committee of the Indiana University School of Medicine and the Methodist Research Institute, Indianapolis, IN, and conformed to the Guide for Care and Use of Labora…
View article: Trichrome Staining Protocol in studies ofEffects of subcutaneous nerve stimulation on nerve sprouting in ambulatory dogs v1
Trichrome Staining Protocol in studies ofEffects of subcutaneous nerve stimulation on nerve sprouting in ambulatory dogs v1 Open
Histology Staining Procedure for tissues from ambulatory dogs after subcutaneous nerve stimulation.
View article: Immunostaining of tissues from dogs with subcutaneous nerve stimulation v1
Immunostaining of tissues from dogs with subcutaneous nerve stimulation v1 Open
Immunostaining of tissue sections from dogs with subcutaneous nerve stimulation.
View article: Cover Image
Cover Image Open
The cover image is based on the Research Article Neuron-specific cilia loss differentially alters locomotor responses to amphetamine in mice by Carlos Ramos et al., https://doi.org/10.1002/jnr.24755.
View article: Recording Intrinsic Nerve Activity at the Sinoatrial Node in Normal Dogs With High-Density Mapping
Recording Intrinsic Nerve Activity at the Sinoatrial Node in Normal Dogs With High-Density Mapping Open
Background: It is known that autonomic nerve activity controls the sinus rate. However, the coupling between local nerve activity and electrical activation at the sinoatrial node (SAN) remains unclear. We hypothesized that we would be able…