Thomas Hamborg
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View article: Co-designed and co-delivered place-based community interventions to reduce inequity in early initiation of antenatal care: findings from the cluster randomised controlled community REACH trial
Co-designed and co-delivered place-based community interventions to reduce inequity in early initiation of antenatal care: findings from the cluster randomised controlled community REACH trial Open
Background Early initiation of antenatal care provides timely screening, advice and support. Inequities in early care initiation exist in high-income countries, but there is scant evidence on effective interventions. The community REACH (R…
View article: Experiences of group antenatal care in the context of the NHS in England: what are the mechanisms by which it functions in this context?
Experiences of group antenatal care in the context of the NHS in England: what are the mechanisms by which it functions in this context? Open
Introduction Group antenatal care is a model where care is provided in groups of around 6–12 women/birthing people, integrating healthcare with information and learning in a participatory approach. There is international evidence of improv…
View article: Digital cognitive behavioural self-management programme for fatigue, pain, and faecal incontinence in inflammatory bowel disease (IBD-BOOST): a multicentre, parallel, randomised controlled trial
Digital cognitive behavioural self-management programme for fatigue, pain, and faecal incontinence in inflammatory bowel disease (IBD-BOOST): a multicentre, parallel, randomised controlled trial Open
UK National Institute for Health and Care Research.
View article: What influences the implementation of group antenatal care in English NHS maternity settings? Findings from a qualitative process evaluation integrated within a randomised controlled trial of Pregnancy Circles
What influences the implementation of group antenatal care in English NHS maternity settings? Findings from a qualitative process evaluation integrated within a randomised controlled trial of Pregnancy Circles Open
Background: Despite universal and generally positive antenatal care in England, some poor experiences and outcomes are reported, especially by minoritised groups. The Pregnancy Circles trial set out to test whether group antenatal care cou…
View article: Optimising fatigue, abdominal pain and faecal incontinence in people with inflammatory bowel disease (IBD-BOOST Optimise): feasibility study of a checklist and algorithm for initial nurse-led management
Optimising fatigue, abdominal pain and faecal incontinence in people with inflammatory bowel disease (IBD-BOOST Optimise): feasibility study of a checklist and algorithm for initial nurse-led management Open
Objective Many people with inflammatory bowel disease (IBD) experience fatigue, pain and faecal incontinence that some feel are inadequately addressed. It is unknown how many have potentially reversible medical issues underlying these symp…
View article: Co-designed and co-delivered place-based community interventions to reduce inequity in early initiation of antenatal care: Findings from the cluster randomised controlled Community REACH trial
Co-designed and co-delivered place-based community interventions to reduce inequity in early initiation of antenatal care: Findings from the cluster randomised controlled Community REACH trial Open
Background: Early initiation of antenatal care provides timely screening, advice and support. Inequities in early care initiation exist in high income countries, but there is scant evidence on effective interventions. The Community REACH t…
View article: Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and the unmet need: a national cross-sectional survey
Fatigue, pain and faecal incontinence in adult Inflammatory Bowel Disease patients and the unmet need: a national cross-sectional survey Open
Background and aims: The co-existence of fatigue, pain and faecal incontinence in people with Inflammatory Bowel Disease (IBD) is unknown. We aimed to determine the presence of and relationship between these symptoms and patients’ desire f…
View article: Impact of pain, fatigue and bowel incontinence on the quality of life of people living with inflammatory bowel disease: A UK cross‐sectional survey
Impact of pain, fatigue and bowel incontinence on the quality of life of people living with inflammatory bowel disease: A UK cross‐sectional survey Open
Background and Aims People with inflammatory bowel disease (IBD) often experience pain, fatigue and bowel incontinence and are at an increased risk of anxiety and depression. Our aim was to assess the impact of these symptoms on health‐rel…
View article: The Adhesive Capsulitis Corticosteroid and Dilation (ACCorD) randomized controlled trial
The Adhesive Capsulitis Corticosteroid and Dilation (ACCorD) randomized controlled trial Open
Aims Is it feasible to conduct a definitive multicentre trial in community settings of corticosteroid injections (CSI) and hydrodilation (HD) compared to CSI for patients with frozen shoulder? An adequately powered definitive randomized co…
View article: P651 A randomised controlled trial of IBD-BOOST, a digital cognitive behavioural self-management programme for fatigue, and/or pain, and/or faecal incontinence in inflammatory bowel disease
P651 A randomised controlled trial of IBD-BOOST, a digital cognitive behavioural self-management programme for fatigue, and/or pain, and/or faecal incontinence in inflammatory bowel disease Open
Background Many people with IBD experience fatigue, pain and faecal incontinence (FI), impacting quality of life (QoL). We developed an interactive digital online self-management intervention (IBD-BOOST) based on a theoretically informed l…
View article: Using healthcare systems data for outcomes in clinical trials: Issues to consider at the design stage
Using healthcare systems data for outcomes in clinical trials: Issues to consider at the design stage Open
Background Healthcare system data (HSD) are increasingly used in clinical trials, augmenting or replacing traditional methods of collecting outcome data. The PRIMORANT study set out to determine when HSD are of sufficient quality and utili…
View article: High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial
High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial Open
Background There is a lack of international consensus regarding the prescription of high-intensity interval training (HIIT) for people with coronary artery disease (CAD) attending cardiac rehabilitation (CR). Aims To assess the clinical ef…
View article: DOP59 What is the relationship between fatigue, pain and urgency in people with inflammatory bowel disease? Results of the IBD-BOOST survey in 8486 participants
DOP59 What is the relationship between fatigue, pain and urgency in people with inflammatory bowel disease? Results of the IBD-BOOST survey in 8486 participants Open
Background Fatigue, pain and faecal incontinence are common in people with IBD. However, little is known about co-existence of these multiple symptoms, how they inter-relate and whether people want help for these symptoms. In qualitative i…
View article: Group antenatal care: findings from a pilot randomised controlled trial of REACH Pregnancy Circles
Group antenatal care: findings from a pilot randomised controlled trial of REACH Pregnancy Circles Open
Background Antenatal care has the potential to impact positively on maternal and child outcomes, but traditional models of care in the UK have been shown to have limitations and particularly for those from deprived populations. Group anten…
View article: Effectiveness and cost-effectiveness of a structured social coaching intervention for people with psychosis (SCENE): protocol for a randomised controlled trial
Effectiveness and cost-effectiveness of a structured social coaching intervention for people with psychosis (SCENE): protocol for a randomised controlled trial Open
Introduction People with psychosis tend to have smaller social networks than both people in the general population and other people with long-term health conditions. Small social networks are associated with poor quality of life. Prelimina…
View article: Cardiovascular Functional Reserve Before and After Kidney Transplant
Cardiovascular Functional Reserve Before and After Kidney Transplant Open
Importance: Restitution of kidney function by transplant confers a survival benefit in patients with end-stage renal disease. Investigations of mechanisms involved in improved cardiovascular survival have relied heavily on static measures …
View article: Minimally invasive non-surgical vs. surgical approach for periodontal intrabony defects: a randomised controlled trial
Minimally invasive non-surgical vs. surgical approach for periodontal intrabony defects: a randomised controlled trial Open
ClinicalTrials.gov, NCT03797807. Registered on 9 January 2019.
View article: Minimally-invasive Non-surgical Vs. Surgical Approach for Periodontal Intrabony Defects: a Randomised Controlled Trial
Minimally-invasive Non-surgical Vs. Surgical Approach for Periodontal Intrabony Defects: a Randomised Controlled Trial Open
Background Periodontal intrabony defects are usually treated surgically with the aim to increase attachment and bone levels and reduce risk of progression. However, recent studies have suggested that a minimally-invasive non-surgical thera…
View article: Effectiveness of a volunteer befriending programme for patients with schizophrenia: randomised controlled trial
Effectiveness of a volunteer befriending programme for patients with schizophrenia: randomised controlled trial Open
Background Befriending by volunteers has the potential to reduce the frequent social isolation of patients with schizophrenia and thus improve health outcomes. However, trial-based evidence for its effectiveness is limited. Aims To conduct…
View article: MINIMALLY-INVASIVE NON-SURGICAL VS. SURGICAL APPROACH FOR PERIODONTAL INTRABONY DEFECTS: A RANDOMISED CONTROLLED TRIAL
MINIMALLY-INVASIVE NON-SURGICAL VS. SURGICAL APPROACH FOR PERIODONTAL INTRABONY DEFECTS: A RANDOMISED CONTROLLED TRIAL Open
Background : Periodontal intrabony defects are usually treated surgically with the aim to increase attachment and bone levels and reduce risk of progression. However, recent studies have suggested that a minimally-invasive non-surgical the…
View article: Characterisation of circulating biomarkers before and after cardiac resynchronisation therapy and their role in predicting CRT response: the COVERT-HF study
Characterisation of circulating biomarkers before and after cardiac resynchronisation therapy and their role in predicting CRT response: the COVERT-HF study Open
Aims Cardiac resynchronisation therapy (CRT) is effective treatment for selected patients with heart failure (HF) but has ~30% non-response rate. We evaluated whether specific biomarkers can predict outcome. Methods A prospective single-ce…
View article: Feasibility and effects of intra-dialytic low-frequency electrical muscle stimulation and cycle training: A pilot randomized controlled trial
Feasibility and effects of intra-dialytic low-frequency electrical muscle stimulation and cycle training: A pilot randomized controlled trial Open
Ten weeks of intra-dialytic LF-EMS or cycling improved cardio-respiratory reserve and muscular strength. For patients who are unable or unwilling to cycle during dialysis, LF-EMS is a feasible alternative.
View article: Correction: Quality of life measures predict cardiovascular health and physical performance in chronic renal failure patients
Correction: Quality of life measures predict cardiovascular health and physical performance in chronic renal failure patients Open
[This corrects the article DOI: 10.1371/journal.pone.0183926.].