Thomas Hrabe
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View article: Cancer3D 2.0: interactive analysis of 3D patterns of cancer mutations in cancer subsets
Cancer3D 2.0: interactive analysis of 3D patterns of cancer mutations in cancer subsets Open
Our knowledge of cancer genomics exploded in last several years, providing us with detailed knowledge of genetic alterations in almost all cancer types. Analysis of this data gave us new insights into molecular aspects of cancer, most impo…
View article: Cancer3D 2.0: interactive analysis of 3D patterns of cancer mutations in cancer subsets
Cancer3D 2.0: interactive analysis of 3D patterns of cancer mutations in cancer subsets Open
Our knowledge of cancer genomics exploded in last several years, providing us with detailed knowledge of genetic alterations in almost all cancer types. Analysis of this data gave us new insights into molecular aspects of cancer, most impo…
View article: Additional file 1: Table S1. of Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework
Additional file 1: Table S1. of Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework Open
shows tools that use three-dimensional structural information from the Protein Data Bank to predict the effect of missense mutations. (XLSX 43 kb)
View article: Revealing aperiodic aspects of solenoid proteins from sequence information
Revealing aperiodic aspects of solenoid proteins from sequence information Open
Motivation: Repeat proteins, which contain multiple repeats of short sequence motifs, form a large but seldom-studied group of proteins. Methods focusing on the analysis of 3D structures of such proteins identified many subtle effects in l…