Thomas J. Böddeker
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View article: Membrane protein condensates polymerize actin and form filopodia
Membrane protein condensates polymerize actin and form filopodia Open
Neuronal morphogenesis is guided by filopodia, dynamically generated plasma membrane protrusions filled with parallel actin filaments. However, how filopodial actin filaments are locally produced, organized, and maintained remains unclear.…
View article: Actin and Microtubules Position Stress Granules
Actin and Microtubules Position Stress Granules Open
Novel analysis tools reveal that stress granules show different affinities to filamentous actin and microtubules, leading to robust stress granule positioning through coupling to actin flow and wetting of microtubules.
View article: Actin and microtubules position stress granules
Actin and microtubules position stress granules Open
Membraneless organelles, composed of protein and nucleic acids, alter the biochemical and physical landscape of the cell. While specific membraneless organelles are found in stereotypical locations, little is known about the physical mecha…
View article: Non-specific adhesive forces between filaments and membraneless organelles
Non-specific adhesive forces between filaments and membraneless organelles Open
Many membraneless organelles are liquid-like domains that form inside the active, viscoelastic environment of living cells through phase separation. To investigate the potential coupling of phase separation with the cytoskeleton, we quanti…
View article: Non-specific adhesive forces between filaments and membraneless organelles
Non-specific adhesive forces between filaments and membraneless organelles Open
Membraneless organelles are liquid-like domains that form inside living cells by phase-separation. While standard physical models of their formation assume their surroundings to be a simple liquid, the cytoplasm is an active viscoelastic e…
View article: Dynamic force measurements on swimming <i>Chlamydomonas</i> cells using micropipette force sensors
Dynamic force measurements on swimming <i>Chlamydomonas</i> cells using micropipette force sensors Open
Flagella and cilia are cellular appendages that inherit essential functions of microbial life including sensing and navigating the environment. In order to propel a swimming microorganism they displace the surrounding fluid by means of per…
View article: Dynamic Force Measurements on Swimming Chlamydomonas Cells using Micropipette Force Sensors
Dynamic Force Measurements on Swimming Chlamydomonas Cells using Micropipette Force Sensors Open
Flagella and cilia are cellular appendages that inherit essential functions of microbial life including sensing and navigating the environment. In order to propel a swimming microorganism they displace the surrounding fluid by means of per…
View article: Supplementary Data from Dynamic force measurements on swimming <i>Chlamydomonas</i> cells using micropipette force sensors
Supplementary Data from Dynamic force measurements on swimming <i>Chlamydomonas</i> cells using micropipette force sensors Open
Exemplary micropipette deflection dataset.
View article: Supplementary Code from Dynamic force measurements on swimming <i>Chlamydomonas</i> cells using micropipette force sensors
Supplementary Code from Dynamic force measurements on swimming <i>Chlamydomonas</i> cells using micropipette force sensors Open
Mathematica code that demonstrates the numerical solution of the relevant equations to obtain the calibration and measurement resonance curves.
View article: Curvature-Guided Motility of Microalgae in Geometric Confinement
Curvature-Guided Motility of Microalgae in Geometric Confinement Open
Microorganisms, such as bacteria and microalgae, often live in habitats consisting of a liquid phase and a plethora of interfaces. The precise ways in which these motile microbes behave in their confined environment remain unclear. Using e…