Thomas J. Guzzo
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View article: Investigating the Usage of Abiraterone in African American Men with Metastatic Prostate Cancer
Investigating the Usage of Abiraterone in African American Men with Metastatic Prostate Cancer Open
Background African American men bear an unequal proportion of metastatic prostate cancer burden. The utilization of second-generation anti-androgens like abiraterone with androgen deprivation therapy (ADT) has become a standard therapy for…
View article: Real-World Management of High-Risk Prostate Cancer Post-Radical Prostatectomy: Insights from a Regional Quality Collaborative
Real-World Management of High-Risk Prostate Cancer Post-Radical Prostatectomy: Insights from a Regional Quality Collaborative Open
Prostate cancer (CaP) remains the most diagnosed malignancy in men, and the incidence of high-grade disease at diagnosis is increasing [...]
View article: A0349 – Controlled comparative outcomes of active surveillance and primary intervention for clinical T1a kidney tumors: A contemporary propensity score and competing risks analysis from the DISSRM prospective study
A0349 – Controlled comparative outcomes of active surveillance and primary intervention for clinical T1a kidney tumors: A contemporary propensity score and competing risks analysis from the DISSRM prospective study Open
View article: The impact of telemedicine on racial and ethnic disparities in oncologic care during the COVID-19 pandemic
The impact of telemedicine on racial and ethnic disparities in oncologic care during the COVID-19 pandemic Open
Codification of COVID-19-era use of telemedicine as a permanent feature of US healthcare has been discussed as it may increase accessibility and equity. This study assesses whether telemedicine is associated with improved differential acce…
View article: Association Between Hospital Efficiency and Quality of Care Among Fee-for-Service Medicare Beneficiaries with Prostate Cancer: A Retrospective Cohort Study
Association Between Hospital Efficiency and Quality of Care Among Fee-for-Service Medicare Beneficiaries with Prostate Cancer: A Retrospective Cohort Study Open
Background: Technical efficiency evaluates a hospital’s economic performance and plays an important role in variations in quality of care and outcomes. The study objective was to examine the association between hospital efficiency and qual…
View article: Appropriateness of Imaging for Low-Risk Prostate Cancer—Real World Data from the Pennsylvania Urologic Regional Collaboration (PURC)
Appropriateness of Imaging for Low-Risk Prostate Cancer—Real World Data from the Pennsylvania Urologic Regional Collaboration (PURC) Open
Imaging for prostate cancer defines the extent of disease. Guidelines recommend against imaging low-risk prostate cancer patients with a computed tomography (CT) scan or bone scan due to the low probability of metastasis. We reviewed imagi…
View article: Oncologic control and predictors of urologic reconstruction after Mohs micrographic surgery for low-risk penile malignancy
Oncologic control and predictors of urologic reconstruction after Mohs micrographic surgery for low-risk penile malignancy Open
Purpose Mohs micrographic surgery (MMS) is a low-risk penile cancer management option. However, contemporary patients’ short-term oncologic control and preoperative characteristics predicting reconstruction needs are undefined. This study …
View article: Efficacy of Intravesical Nadofaragene Firadenovec for Patients With Bacillus Calmette-Guérin–Unresponsive Nonmuscle-Invasive Bladder Cancer: 5-Year Follow-Up From a Phase 3 Trial
Efficacy of Intravesical Nadofaragene Firadenovec for Patients With Bacillus Calmette-Guérin–Unresponsive Nonmuscle-Invasive Bladder Cancer: 5-Year Follow-Up From a Phase 3 Trial Open
At 60 months, nadofaragene firadenovec-vncg allowed bladder preservation in nearly half of the patients and proved to be a safe option for BCG-unresponsive nonmuscle-invasive bladder cancer.
View article: Protocol of the Comparison of Intravesical Therapy and Surgery as Treatment Options (CISTO) study: a pragmatic, prospective multicenter observational cohort study of recurrent high-grade non-muscle invasive bladder cancer
Protocol of the Comparison of Intravesical Therapy and Surgery as Treatment Options (CISTO) study: a pragmatic, prospective multicenter observational cohort study of recurrent high-grade non-muscle invasive bladder cancer Open
Background Bladder cancer poses a significant public health burden, with high recurrence and progression rates in patients with non-muscle-invasive bladder cancer (NMIBC). Current treatment options include bladder-sparing therapies (BST) a…
View article: Association between hospital competition and quality of prostate cancer care
Association between hospital competition and quality of prostate cancer care Open
View article: Diminished Short-Term Efficacy of Reduced-Dose Induction BCG in the Treatment of Non-Muscle Invasive Bladder Cancer
Diminished Short-Term Efficacy of Reduced-Dose Induction BCG in the Treatment of Non-Muscle Invasive Bladder Cancer Open
The ongoing Bacillus Calmette-Guérin (BCG) shortage has created challenges for the treatment of non-muscle invasive bladder cancer (NMIBCa). Our objective was to evaluate the efficacy of reduced-dose induction BCG (RD-iBCG) compared to ful…
View article: Multiparametric MRI is not sufficient for prostate cancer staging: A single institutional experience validated by a multi-institutional regional collaborative
Multiparametric MRI is not sufficient for prostate cancer staging: A single institutional experience validated by a multi-institutional regional collaborative Open
Despite enthusiasm for its use, in a real-world setting, mpMRI appears to be a poor staging study for localized CaP and is unreliable as the sole means of staging patients prior to prostatectomy. mpMRI should be used cautiously as a stagin…
View article: Trajectory of Depression among Prostate Cancer Patients: A Secondary Analysis of a Randomized Controlled Trial
Trajectory of Depression among Prostate Cancer Patients: A Secondary Analysis of a Randomized Controlled Trial Open
Background: While psychological difficulties, such as depression, among prostate cancer patients are known, their longitudinal burden remains understudied. We assessed the burden of depression across low-, intermediate- and high-risk prost…
View article: Continuity of care and advanced prostate cancer
Continuity of care and advanced prostate cancer Open
Background Continuity of care is an important element of advanced prostate cancer care due to the availability of multiple treatment options, and associated toxicity. However, the association between continuity of care and outcomes across …
View article: Table of Contents
Table of Contents Open
View article: Model Risk Scores May Underestimate Rate of Biochemical Recurrence in African American Men with Localized Prostate Cancer: A Cohort Analysis of Over 3000 Men
Model Risk Scores May Underestimate Rate of Biochemical Recurrence in African American Men with Localized Prostate Cancer: A Cohort Analysis of Over 3000 Men Open
Introduction: This study aims to determine if there is a difference in the CAPRA and Kattan model-adjusted risk of biochemical recurrence (BCR) and/or adverse pathology between African American (AAM) and Caucasian men (CM) undergoing radic…
View article: Table of Contents
Table of Contents Open
View article: A Tribute to Dr. Douglas A. Canning: Surgeon, Educator, Friend
A Tribute to Dr. Douglas A. Canning: Surgeon, Educator, Friend Open
View article: Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures
Non-infectious complications following transrectal prostate needle biopsy – Outcomes from over 8000 procedures Open
View article: Prognostic significance of sarcomatoid features in metastatic renal cell carcinoma treated with cytoreductive nephrectomy and targeted therapy.
Prognostic significance of sarcomatoid features in metastatic renal cell carcinoma treated with cytoreductive nephrectomy and targeted therapy. Open
mRCC with sarcomatoid features treated with CN and TT has a very poor and drastically different prognosis compared with mRCC without sarcomatoid features. With the expansion of systemic RCC therapies, investigation is needed to optimize tr…
View article: Antiadenovirus Antibodies Predict Response Durability to Nadofaragene Firadenovec Therapy in BCG-unresponsive Non–muscle-invasive Bladder Cancer: Secondary Analysis of a Phase 3 Clinical Trial
Antiadenovirus Antibodies Predict Response Durability to Nadofaragene Firadenovec Therapy in BCG-unresponsive Non–muscle-invasive Bladder Cancer: Secondary Analysis of a Phase 3 Clinical Trial Open
View article: PD03-02 RACIAL DISPARITIES IN PROSTATE CANCER TREATMENT IN A MULTI-INSTITUTIONAL REGIONAL COLLABORATIVE
PD03-02 RACIAL DISPARITIES IN PROSTATE CANCER TREATMENT IN A MULTI-INSTITUTIONAL REGIONAL COLLABORATIVE Open
You have accessJournal of UrologyHealth Services Research: Practice Patterns, Quality of Life and Shared Decision Making I (PD03)1 Sep 2021PD03-02 RACIAL DISPARITIES IN PROSTATE CANCER TREATMENT IN A MULTI-INSTITUTIONAL REGIONAL COLLABORAT…
View article: MP05-04 CLINICALLY SIGNIFICANT PROSTATE CANCER DETECTION RATES ON MRI GUIDED FUSION NEEDLE BIOPSY - EXPERIENCE FROM THE PENNSYLVANIA UROLOGIC REGIONAL COLLABORATIVE
MP05-04 CLINICALLY SIGNIFICANT PROSTATE CANCER DETECTION RATES ON MRI GUIDED FUSION NEEDLE BIOPSY - EXPERIENCE FROM THE PENNSYLVANIA UROLOGIC REGIONAL COLLABORATIVE Open
You have accessJournal of UrologyProstate Cancer: Detection & Screening I (MP05)1 Sep 2021MP05-04 CLINICALLY SIGNIFICANT PROSTATE CANCER DETECTION RATES ON MRI GUIDED FUSION NEEDLE BIOPSY - EXPERIENCE FROM THE PENNSYLVANIA UROLOGIC REGIONA…
View article: Assessment of Prostate Cancer Treatment Among Black and White Patients During the COVID-19 Pandemic
Assessment of Prostate Cancer Treatment Among Black and White Patients During the COVID-19 Pandemic Open
In this large multi-institutional regional collaborative cohort study, the odds of PCa surgery were lower among Black patients compared with White patients during the initial wave of the COVID-19 pandemic. Although localized PCa does not r…
View article: Surgical Delay and Pathological Outcomes for Clinically Localized High-Risk Prostate Cancer
Surgical Delay and Pathological Outcomes for Clinically Localized High-Risk Prostate Cancer Open
In this cohort study of patients who underwent radical prostatectomy within 180 days of diagnosis for high-risk prostate cancer, radical prostatectomy for high-risk prostate cancer could be safely delayed up to 6 months after diagnosis.
View article: Financial incentives and wearable activity monitors to increase ambulation after cystectomy: A randomized controlled trial
Financial incentives and wearable activity monitors to increase ambulation after cystectomy: A randomized controlled trial Open
View article: Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial
Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial Open
View article: Management of Large Allograft Mass Following Living Donor Kidney Transplantation
Management of Large Allograft Mass Following Living Donor Kidney Transplantation Open
View article: Detection of renal artery pseudo-aneurysm six months after robotic assisted partial nephrectomy in a patient whose only complaint was flank pain
Detection of renal artery pseudo-aneurysm six months after robotic assisted partial nephrectomy in a patient whose only complaint was flank pain Open
View article: Helping Men with Prostate Cancer Determine Their Preferences for Treatment
Helping Men with Prostate Cancer Determine Their Preferences for Treatment Open
Results Summary Download Summary Español (pdf) Audio Recording (mp3) Results Summary What was the research about? Men with localized prostate cancer, or cancer that hasn’t spread beyond the prostate gland, have many treatment options, incl…