Thomas Kirschning
YOU?
Author Swipe
View article: PANDA: Development and evaluation of a nursing competence team of respiratory therapists and advanced practice nurses to optimize the weaning process
PANDA: Development and evaluation of a nursing competence team of respiratory therapists and advanced practice nurses to optimize the weaning process Open
Background Weaning critically ill patients from mechanical ventilation (MV) is an important challenge of intensive care unit (ICU) management. Internationally, MV is often supported by respiratory therapists (RT) as specially trained nurse…
View article: The international, prospective CytOSorbⓇ treatMent Of critically ill patientS (COSMOS) registry: Interim results from the first 150 patients
The international, prospective CytOSorbⓇ treatMent Of critically ill patientS (COSMOS) registry: Interim results from the first 150 patients Open
The COSMOS registry highlights CS-associated improvements in lactate, creatinine, norepinephrine needs, fluid balance, and oxygenation. Mortality was favorable compared with risk-based predictions.Trial registration Clinicaltrials.gov Iden…
Treatment of Refractory Cardiac Arrest by Controlled Reperfusion of the Whole Body: A Multicenter, Prospective Observational Study Open
Background: Survival following cardiac arrest (CA) remains poor after conventional cardiopulmonary resuscitation (CCPR) (6–26%), and the outcomes after extracorporeal cardiopulmonary resuscitation (ECPR) are often inconsistent. Poor surviv…
Ground truth labels challenge the validity of sepsis consensus definitions in critical illness Open
Background Sepsis is the leading cause of death in the intensive care unit (ICU). Expediting its diagnosis, largely determined by clinical assessment, improves survival. Predictive and explanatory modelling of sepsis in the critically ill …
Differential Network Testing Reveals Diverging Dynamics of Organ System Interactions for Survivors and Non-survivors in Intensive Care Medicine Open
Statistical network analyses have become popular in many scientific disciplines, where an important task is to test for differences between two networks. We describe an overall framework for differential network testing procedures that var…
Results of the CAPSID randomized trial for high-dose convalescent plasma in patients with severe COVID-19 Open
BACKGROUNDCOVID-19 convalescent plasma (CCP) has been considered a treatment option for COVID-19. This trial assessed the efficacy of a neutralizing antibody containing high-dose CCP in hospitalized adults with COVID-19 requiring respirato…
Maintaining oxygen delivery is crucial to prevent intestinal ischemia in critical ill patients Open
Background Intestinal ischemia is a common complication with obscure pathophysiology in critically ill patients. Since insufficient delivery of oxygen is discussed, we investigated the influence of oxygen delivery, hemoglobin, arterial oxy…
High Dose Convalescent Plasma in COVID-19: Results from the Randomized Trial CAPSID Open
Rationale COVID-19 convalescent plasma (CCP) has been considered a treatment option in COVID-19. Objectives To assess the efficacy of neutralizing antibody containing high-dose CCP in hospitalized adults with COVID-19 requiring respiratory…
Lung Protection vs. Infection Resolution: Interleukin 10 Suspected of Double-Dealing in COVID-19 Open
The pathological processes by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection that make the virus a major threat to global health are insufficiently understood. Inefficient viral clearance at any stage is a hallmark …
A quantitative CT parameter for the assessment of pulmonary oedema in patients with acute respiratory distress syndrome Open
Objectives The aim of this study was to establish quantitative CT (qCT) parameters for pathophysiological understanding and clinical use in patients with acute respiratory distress syndrome (ARDS). The most promising parameter is introduce…
View article: Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO)
Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO) Open
Background Significant long-term reduction in health-related quality of life (HRQoL) is often observed in survivors of the acute respiratory distress syndrome (ARDS), and return to work (RtW) is limited. There is a paucity of data regardin…
The quality of acute intensive care and the incidence of critical events have an impact on health-related quality of life in survivors of the acute respiratory distress syndrome – a nationwide prospective multicenter observational study Open
Background: Initial treatment (ventilator settings, rescue therapy, supportive measures), and prevention of critical events improve survival in ARDS patients, but little data exists on its effect on health-related quality of life (HRQOL) a…
Additional file 4 of Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO) Open
Additional file 4: Excel File. Table 7. Linear Regression Analyses of Health-related Quality of Life after 6 months on Quality of Care. a adjusted for age, sex, severity of ARDS; b adjusted for age, sex, severity of ARDS, BMI, Education sc…
Additional file 3 of Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO) Open
Additional file 3: Excel File. Table 6. Linear Regression Analyses of Health-related Quality of Life after 3 months on Quality of Care. a adjusted for age, sex, severity of ARDS; b adjusted for age, sex, severity of ARDS, BMI, Education sc…
Additional file 1 of Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO) Open
Additional file 1: Excel File. Table 4. Socio-demographic and general medical characteristics of 12 months respondents. a derived from educational and professional level22, considered for regression analyses. SAPS-II score: Simplified Acut…
Additional file 2 of Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO) Open
Additional file 2: Excel File. Table 5. Linear Regression Analyses of Health-related Quality of Life after 12 months on Quality of Care. a adjusted for age, sex, severity of ARDS; b adjusted for age, sex, severity of ARDS, BMI, Education s…
Outcome of Oral and Intra-arterial Nimodipine Administration After Aneurysmal Subarachnoid Haemorrhage – A Single-centre Study Open
Oral nimodipine administration improved clinical outcome of patients after aSAH and should be administered routinely for such patients.
German-wide prospective DACAPO cohort of survivors of the acute respiratory distress syndrome (ARDS): a cohort profile Open
Purpose While most research focuses on the association between medical characteristics and residual morbidity of survivors of the acute respiratory distress syndrome (ARDS), little is known about the relation between potentially modifiable…
P3503Bedside implantation of a new temporary vena cava inferior filter: safety and efficacy results of the European ANGEL-Registry Open
Background: While the importance of patients' quality of life (QoL) in heart failure is increasingly been acknowledged and has become a treatment target, the burden of an acute pulmonary embolism (PE) on patient' QoL has received little at…